Application of 7P peptide in preventing or treating pneumonia
A pneumonia and lung technology, applied in the field of medicine, can solve the problems of no observation of 7P and its derivatives pneumonia lesions symptoms, no 7P and its derivatives found, etc.
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[0041] Example 1. The protective effect of immune 7-peptide drugs on pneumonia in mice
[0042] 1. Experimental materials
[0043] 1.1 Animals:
[0044] Clean-grade ICR mice, weighing 18g-22g, male and female, were provided by the Experimental Animal Center of Nantong University (experimental animal production license: SCXK (Su) 2008-0010; experimental animal use license: SYXK (Su) 2007-- 0030).
[0045] 1.2 Drugs:
[0046] The peptide whose sequence is GQTYTSG (hereinafter referred to as "immune 7 peptide") is dissolved in physiological saline before use.
[0047] Positive control drug: dexamethasone injection, provided by Guizhou Huasheng Pharmaceutical Co., Ltd., batch number: 071017, specification: 5mg / ml / bottle.
[0048] 1.3 Drug preparation, dosage and grouping
[0049] Dexamethasone injection group (administration dose is 0.9mg / kg), immune 7 peptide drug high, medium and low dose groups were 250μg / kg, 125μg / kg, 62.5μg / kg, blank control group, model group were given...
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