Chinese medicinal composition for treating climacteric syndromes and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating menopausal syndrome and its preparation field, can solve the problems of large side effects, unsatisfactory treatment effect and the like, and achieve the effects of small side effects, reduction of the number of autonomous activities, and remarkable curative effect.

Inactive Publication Date: 2012-07-04
朱鸿龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the defects of unsatisfactory therapeutic effects and large side effects of existing Western medicines for treating menopausal syndrome, and to provide a traditional Chinese medicine composition for treating menopausal syndrome with strong pertinence, significant curative effect and small side effects

Method used

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  • Chinese medicinal composition for treating climacteric syndromes and preparation method thereof
  • Chinese medicinal composition for treating climacteric syndromes and preparation method thereof
  • Chinese medicinal composition for treating climacteric syndromes and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: the preparation of pharmaceutical composition of the present invention

[0033] Step a: The preparation method of the Radix Paeoniae Alba extract: take 1600 g of Radix Paeoniae Alba, add 16000 ml, 12000 ml, and 9600 ml of 70% ethanol, heat and reflux for three times for 1.5 hours, 1 hour, and 1 hour, combine the extracts, filter, The ethanol was recovered from the filtrate, concentrated to dryness, vacuum-dried at 60°C, taken out, crushed, and passed through a 40-mesh sieve to obtain about 270 g of dry paste, which was set aside;

[0034] Step b: Preparation of Ligustrum lucidum extract: take 1400 g of Ligustrum lucidum and add 14000 ml and 11200 ml of 80% ethanol, heat and reflux to extract twice for 2 hours and 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate, Concentrate to 1400ml, add water to 2800ml, let it stand overnight, centrifuge, take the precipitate, dry it, crush it, pass through a 40-mesh sieve, and obtain about...

Embodiment 2

[0037] Embodiment 2: the capsule preparation of pharmaceutical composition of the present invention

[0038] Step a: The preparation method of the Radix Paeoniae Alba extract: take 1000 g of Radix Paeoniae Alba, add 10000 ml, 8000 ml, and 6000 ml of 70% ethanol, heat and reflux three times for 1.5 hours, 1 hour, and 1 hour, combine the extracts, filter, The ethanol was recovered from the filtrate, concentrated to dryness, vacuum-dried at 60°C, taken out, pulverized, and passed through a 40-mesh sieve to obtain about 170 g of dry paste, which was set aside;

[0039] Step b: Preparation of Ligustrum lucidum extract: take 800 g of Ligustrum lucidum and add 8000 milliliters, 6400 milliliters of 80% ethanol, heat and reflux to extract twice for 2 hours and 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate, When concentrated to 1:1, add water until the medicinal material content is 1:2, let it stand overnight, centrifuge, take the precipitate, dry it, p...

Embodiment 3

[0042] Embodiment 3: the capsule preparation of pharmaceutical composition of the present invention

[0043] Step a: The preparation method of Radix Paeoniae Alba extract: take 1333g Radix Paeoniae Alba, add 13330 ml, 10664 ml, 7998 ml of 70% ethanol, heat and reflux for three times for 1.5 hours, 1 hour, 1 hour, combine the extracts, filter, The ethanol was recovered from the filtrate, concentrated to dryness, vacuum-dried at 60°C, taken out, crushed, and passed through a 40-mesh sieve to obtain about 226g of dry paste, which was set aside;

[0044] Step b: Take 1111g of Ligustrum lucidum, add 11110 ml, 8888 ml of 80% ethanol, heat and reflux to extract twice, time 2 hours, 1 hour, combine the extracts, filter, recover ethanol from the filtrate, concentrate to 1:1, add water Until the content of the medicinal material is 1:2, let it stand overnight, centrifuge, take the precipitate, dry it, pulverize it, and pass through a 40-mesh sieve to obtain about 66g of dry paste, which...

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Abstract

The invention relates to the field of Chinese medicaments, and discloses a Chinese medicinal composition for treating climacteric syndromes. Preferably, the Chinese medicinal composition comprises the following raw materials in part by weight: 1,000 to 1,600 parts of white paeony root, 800 to 1,400 parts of glossy privet fruit, and 800 to 1,400 parts of amur corktree bark. The invention also provides a preparation method of the Chinese medicinal composition. The Chinese medicinal composition for treating the climacteric syndromes has the advantages of obvious curative effect, simple formula and small side effects. The preparation method has the advantages of high extraction rate, simple operation, and suitability for industrialized production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating climacteric syndrome and a preparation method thereof. Background technique [0002] Menopausal syndrome refers to a group of clinical syndromes characterized by dysfunction of the hypothalamus-pituitary-ovarian axis due to the gradual decline of ovarian function and the decline of estrogen levels in women before and after menopause. , also known as perimenopausal syndrome. According to foreign statistics, 84.2% of women have symptoms during perimenopause. According to the 2000 national census data, there are about 120 million women aged 45-65 in my country. Epidemiological studies show that among this population More or less, mild or severe menopause-related symptoms occurred in at least 60%. With the aging of society and the prolongation of women's life expectancy, the incidence of this disease has an upward tr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/00A61K36/756A61K9/16A61K9/48A61P15/12
Inventor 朱鸿龙
Owner 朱鸿龙
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