Chinese medicinal composition for treating protrusion of lumbar intervertebral disci and preparation method thereof

A technology of lumbar disc herniation and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problem of no breakthrough in the surgical treatment of lumbar disc herniation, and achieve the purpose of filling lumbar disc herniation and side effects Small, fully extracted effects

Inactive Publication Date: 2010-11-10
夏建龙 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Foreign medicine has a history of more than 100 years of intuitive exploration of this disease. In 1934, Miter and Barr jointly reported the surgical treatment of 19 cases of lumbar disc herniation, thus creating a new era of surgical treatment of lumbar disc herniation. There are generally two views on the treatment of this disease in the medical circles at home and abroad. One is to actively advocate surgical treatment. Where the patient has clinical symptoms and is clearly diagnosed by physical examination, surgical treatment is advocated. Surgical treatment did not exceed the scope of foreign surgery
The second is to advocate conservative treatment, do not rule out surgery, adopt traditional methods, Chinese and Western medicine, pelvic traction, epidural seal and other comprehensive treatment of traditional Chinese medicine and integrated Chinese and Western medicine. Most patients can obtain satisfactory curative effect, so the latter easily accepted by patients
Because surgery is trauma after all, and surgical treatment has many disadvantages, such as deformity of lumbosacral nerves, congenital heterosexual vertebra, etc., physical examination often does not match clinical signs, so the success rate of surgery hovers around 80% for a long time. It is not uncommon for people to blindly pursue surgery and cause medical disputes

Method used

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  • Chinese medicinal composition for treating protrusion of lumbar intervertebral disci and preparation method thereof
  • Chinese medicinal composition for treating protrusion of lumbar intervertebral disci and preparation method thereof
  • Chinese medicinal composition for treating protrusion of lumbar intervertebral disci and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] The preparation of embodiment 1 pharmaceutical granule of the present invention

[0078] Prescription: Zhichuan Aconitum 120g, Ephedra 100g, Astragalus 200g, Paeoniae Alba 200g

[0079] Licorice 60g, Mildew Spatholobus 150g, Clematis 150g, Guizhi 100g

[0080] Add 8 times the total weight of each raw medicinal material to the water, soak for 1 hour, decoct twice for 2 hours each time, combine the filtrate, concentrate under reduced pressure to a relative density of 1.20 at 50-60°C, add ethanol while slightly hot Stir evenly so that the alcohol content of the medicinal solution reaches 60%, let it stand for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure and continue to concentrate to a relative density of 1.25 at 50-60°C to obtain the active component of the medicine of the present invention. Granulate according to the weight ratio of active ingredient: sugar powder: dextrin (1:1:2.5), dry at 80°C, size the granules and mix them unifo...

Embodiment 2

[0081] The preparation of embodiment 2 pharmaceutical capsules of the present invention

[0082] Prescription: Zhichuan Aconitum 110g, Ephedra 90g, Astragalus 150g, Paeoniae Alba 150g

[0083] Licorice 40g, Mildew Spatholobus 100g, Clematis 100g, Guizhi 120g

[0084] Add each raw medicinal material to 5 times the total weight of the medicinal material in water, soak for 1 hour, decoct 3 times, 2 hours each time, combine the filtrate, concentrate under reduced pressure to a relative density of 1.25 at 50-60 ° C, add ethanol while slightly hot Stir evenly so that the alcohol content of the medicinal solution reaches 50%, let it stand for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure and continue to concentrate at 50-60° C. when the relative density is 1.25, the active component of the medicine of the present invention is obtained. The active component is added to dextrin and other commonly used pharmaceutically prescribed excipients to prepa...

Embodiment 3

[0085] The preparation of embodiment 3 pharmaceutical tablet of the present invention

[0086] Prescription: Zhichuan Aconitum 130g, Ephedra 110g, Astragalus 250g, Paeoniae Alba 250g

[0087] Licorice 80g Milletah 200g Clematis 200g Guizhi 80g

[0088] Add 10 times the total weight of each raw medicinal material in water, soak for 2 hours, decoct 4 times, 1 hour each time, combine the filtrate, concentrate under reduced pressure to a relative density of 1.15 at 50-60°C, add ethanol while slightly hot Stir evenly so that the alcohol content of the medicinal solution reaches 70%, let it stand for 24 hours, filter, recover the ethanol from the filtrate under reduced pressure and continue to concentrate to a relative density of 1.20 at 50-60°C to obtain the active component of the medicine of the present invention. The active ingredient is added into commonly used pharmaceutically prescribed excipients such as starch to compress the tablet.

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Abstract

The invention discloses a Chinese medicinal composition for treating protrusion of the lumbar intervertebral disci, which is characterized in that: the Chinese medicinal composition is prepared from the following raw material medicaments in part by weight: 11 to 13 parts of prepared common monkshood mother root, 9 to 11 parts of ephedra, 15 to 25 parts of astragalus, 15 to 25 parts of white paeony root, 4 to 8 parts of liquorice root, 10 to 20 parts of suberect spatholobus stem, 10 to 20 parts of clematis root and 8 to 12 parts of cassia twig. The Chinese medicinal composition for treating the protrusion of the lumbar intervertebral disci has the advantages of obvious curative effect, no obvious toxic or side effect, no contraindication and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating lumbar intervertebral disc herniation and a preparation method thereof. Background technique: [0002] Prolapse of lumbar intervertebral disc is a clinically common and frequently-occurring disease. According to relevant statistics, the incidence rate in my country is 1‰, and in developed countries abroad it is 1.5‰. There are many treatment methods for this disease, but in summary, it is nothing more than surgery and There are two types of non-surgical treatment. Foreign medicine has a history of more than 100 years of intuitive exploration of this disease. In 1934, Miter and Barr jointly reported the surgical treatment of 19 cases of lumbar disc herniation, thus creating a new era of surgical treatment of lumbar disc herniation. There are generally two views on the treatment of this diseas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/716A61P19/08
Inventor 夏建龙周福贻
Owner 夏建龙
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