Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Sterilizing composition

一种组合物、衍生物的技术，应用在外科器械灭菌的组合物领域，能够解决易受进入污物的影响、泡沫控制短暂等问题，达到优良去污能力、提高吸收、改善清洁效果的效果

Active Publication Date: 2010-12-29
WHITELEY
View PDF11 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Foam control is transient and susceptible to ingress of dirt

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Sterilizing composition
  • Sterilizing composition
  • Sterilizing composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Combine the following ingredients in the order listed:

[0081] Deionized water 91.9g

[0082] Neodol 91-6 TM (Shell) 0.50g

[0083] Plurafac LF-221 TM (BASF) 0.40g

[0084] Triethylene glycol 3.80g

[0085] Add buffer, dye

[0086] Adjust pH to 6.3-6.5

[0087] 50% Pharmaceutical Grade Glutaraldehyde 4.5g

[0088] The foam height that this composition of the present invention produces is compared with 100% Neodol 91-6 TM (Equivalent to the prior art composition disclosed in US Patent No. 4,748,276) The foam height of the prepared composition was compared. This composition (Neodol 91-6 TM / Plurac LF221 TM ) was compared to the foam height obtained with the composition disclosed in US Pat. No. 4,748,276. The results are shown in Figure 1.

[0089] As can be seen from the figure, when the composition disclosed in U.S. Patent 4,748,276 (containing Neodol 91-6 TM ) by adding 0.4% Plurac LF221 TM After that, the foam height is the same as without Plurac LF221 ...

Embodiment 2

[0092] The same composition as Example 1 was prepared except that 20% Neodol 91-6 TM and 80% Antarox LF330 TM (Rhodia) constitutes a surfactant concentration other than 0.5%.

[0093] Comparing the foam height produced by this composition with 100% Neodol 91-6 TM (Equivalent to the prior art composition disclosed in US Patent No. 4,748,276) The foam height of the prepared composition was compared. This composition (Neodol 91-6 TM / Antarox LF330 TM ) was compared to the foam height obtained with the composition disclosed in US Pat. No. 4,748,276. The results are shown in Figure 2.

[0094] As shown in the figure, when composed of 20% Neodol 91-6 TM and 80% Antarox LF330 TM At a make-up surfactant concentration of 0.5%, the composition of the invention produced an exceptionally rapid decrease in foam height compared to the prior art composition.

[0095] The composition of the present invention has a surface tension of 22.4 dynes / cm. The surface tension of the prior art...

Embodiment 3

[0097] The same composition as Example 1 was prepared except that 20% Neodol 91-6 TM and 80% Antarox BL240 TM (Rhodia) constitutes a surfactant concentration other than 0.5%.

[0098] Comparing the foam height produced by this composition with 100% Neodol 91-6 TM (Equivalent to the prior art composition disclosed in US Patent No. 4,748,276) The foam height of the prepared composition was compared. This composition (Neodol 91-6 TM / Antarox BL240 TM ) was compared to the foam height obtained with the composition disclosed in US Pat. No. 4,748,276. The results are shown in Figure 3.

[0099] As shown in the figure, when composed of 20% Neodol 91-6 TM and 80% Antarox BL240 TM At a surfactant concentration of 0.5%, the compositions of the present invention produced significantly lower foam heights than prior art compositions.

[0100] The surface tension of the composition of the present invention is 29.0 dynes / cm. The surface tension of the prior art composition is 28 dyn...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Disclosed is a sterilizing composition including (i) at least one mono or dialdehyde; (ii) at ieast one glycol or polyol or derivative thereof; (iii) a non-ionic first surfactant; and (iv) a second surfactant having a cloud point in the range of about 30 DEG C to 50 DEG C. Also disclosed is a sterilizing composition including (i) at least one mono or dialdehyde;(ii) at least one glycol or polyol or derivative thereof; (iii) a non-ionic first surfactant; and (iv) a second surfactant, wherein the second surfactant is a quaternary ammonium compound, A process for preparing the compositions of the invention is also disclosed. The compositions of the invention are low or substantially non-foaming under high pressure, high temperature conditions, thus allowing maximum benefit from the new, more reliable, generation of automated endoscope reprocessing machine.

Description

field of invention [0001] The present invention relates to compositions and methods for the sterilization of surgical instruments, particularly endoscopic surgical instruments. Background of the invention [0002] Cleaning and sterilization of complex endoscopic surgical instruments presents a major question of how to achieve reproducible standards for both cleanliness and biosafety. [0003] As endoscopic instruments used in "critical hole surgery" expand to cover more types of routine interventional procedures, the structure of new instruments becomes more and more complex, so their maintenance between surgical procedures more difficult. [0004] Unfortunately, current endoscope detergents suffer from the problem of foaming under high pressure. Due to the complexities involved in the construction of surgical instruments, there are issues related to cleaning efficiency that require increased miniaturization of the tubing systems through which surgical illumination light, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L2/18A01N25/30
CPCA01N35/02A01N35/04A01N25/30A01N31/02A01N33/12A01N2300/00A61L2/18
Inventor R·K·怀特利M·E·卡拉曼G·S·怀特利
Owner WHITELEY
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com