Application of hexachlorophene in resistance to Eimeria tenella
A technology of Eimeria tenella and hexachlorophenol, which is applied in the application field of hexachlorophenol in anti-Eimeria tenella, can solve the problem that it is impossible to infer anti-Eimeria tenella and has not yet seen anti-eimeria tenurei of hexachlorophenol. Eimeria, poor effect, etc.
Active Publication Date: 2011-04-20
广东省农业科学院兽医研究所
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Problems solved by technology
[0005] Hexachlorophene has good antibacterial effect on Gram-positive bacteria, but poor effect on Gram-negative bacteria, and has no effect on Mycobacterium tuberculosis and spores
[0007] So far, there has been no report on the effect of hexachlorophene against Eimeria tenella, and it is impossible to infer whether hexachlorophene has an anti-Eimeria tenae effect based on the known properties of hexachlorophene
Method used
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example 1
[0032] Preparation of powder: get 30g of hexachlorophene (content not less than 99%) and 70g of starch and mix well.
[0033] Usage and dosage: Make every 100 kg of feed mixed with 15 grams of the hexachlorophene, and feed according to the daily food intake.
example 2
[0035] Preparation of suspending agent: take 30g of hexachlorophene (content not less than 99%), add propylene glycol and stir, and dissolve to 100 milliliters.
[0036] Usage and dosage: the suspending agent is mixed in drinking water, so that the concentration of hexachlorophene is 7.5g / 100Kg water, and then drink water according to the daily drinking water amount.
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The invention discloses an application of hexachlorophene in preparation of a drug resistant to Eimeria tenella. The hexachlorophene and pharmaceutically acceptable excipients are evenly mixed and added in water or feed. The animal infection experiments confirm that the anticoccidial index (ACI) of the hexachlorophene reaches over 168.8, and the hexachlorophene has better effect in resistance to the Eimeria tenella.
Description
technical field [0001] The invention relates to a new application of hexachlorophene, in particular to the application of hexachlorophene in resisting Eimeria tenella. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers the intensive chicken industry production, and the economic loss caused by it is as high as more than 2.5 billion pounds every year. The most harmful is Eimeria tenella. Although my country has no accurate statistics on this so far, the most conservative estimate is that the loss should not be less than 2.5 billion RMB. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Hexachlorophene (Hexachlorophene), chemical name, 2,2'-methylene bis(3,4,6-trichlorophenol), also known as methylene trichlorophene; toad...
Claims
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Inventor 孙铭飞蔡建平谢明权覃宗华吕敏娜袁建丰李祥瑞吴彩艳王志军余劲术
Owner 广东省农业科学院兽医研究所