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Traditional Chinese medicinal composition and preparation method for granules thereof

A composition and technology of traditional Chinese medicine, applied in the field of preparation of traditional Chinese medicine composition and its granules, to achieve the effect of less toxic and side effects, good effect, and blood pressure lowering effect

Inactive Publication Date: 2011-11-16
BIOLOGY INST OF SHANDONG ACAD OF SCI
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  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

However, long-term use of these drugs will cause varying degrees of liver and kidney toxicity.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0026] The jellyfish skin was washed 3 times with tap water, soaked in 10 times the amount of water for 12 h, cut into pieces, and mashed with a tissue grinder. Measure the moisture and protein content of the jellyfish homogenate, add water for enzymolysis according to the measurement results, make the ratio of protein to water 1:50, add 3000 u of pepsin per gram of protein, adjust the pH to 3.0, and stir at 37°C Enzymolysis for 4 h; then adjust the pH of the enzymolysis solution to 5.5, adjust the temperature to 50°C, add 3000 u of papain per gram of protein, and stir the enzymolysis for 1 h. Centrifuge at r / min for 15 min, take the supernatant, concentrate under reduced pressure at 50°C until the solid content is 50% (measured at 50°C), freeze-dry (-30°C), and crush through a 120-mesh sieve to obtain jellyfish collagen peptide powder .

[0027] Take the three traditional Chinese medicines of eucommia ulmoides, kudzu root and wild chrysanthemum, add water and decoct three ti...

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Abstract

The invention provides a traditional Chinese medicinal composition and a preparation method for granules thereof. Jellyfish skin, cortex eucommiae, puerariae and mother chrysanthemum form a prescription; and the traditional Chinese medicinal composition is prepared by the following steps of: firstly, hydrolyzing the jellyfish skin by using pepsase and papain sequentially to obtain jellyfish skin proteolysis solution, and performing vacuum concentration and freeze drying to obtain jellyfish skin collagen peptide powder; secondly extracting the three traditional Chinese medicines, namely the cortex eucommiae, the puerariae and the mother chrysanthemum by using a water extraction and alcohol precipitation method to obtain extracting solution, and performing concentration and vacuum drying toobtain traditional Chinese medicinal extract powder; and finally, mixing the two extracts according to a proportion to obtain the traditional Chinese medicinal composition. The granules are prepared from the traditional Chinese medicinal composition serving as a raw material, and sugar powder and dextrin which serve as auxiliary materials.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof. Background technique [0002] Hypertension is a clinical syndrome characterized by elevated arterial systolic or diastolic blood pressure, which is often accompanied by systemic diseases of heart disease, blood vessels, brain and kidneys and other organs and structures. Complications of various diseases such as blood vessels and an important risk factor leading to stroke, promoting arteriosclerosis, and coronary heart disease. The prevalence of high blood pressure in developed countries is above 20%, and the average prevalence of all countries in the world is 10-20%, and the population is widely distributed. Not only the elderly and middle-aged people have a high prevalence, even children also suffer from high blood pressure (the incidence rate in foreign countries is 0.6-11%, and it is 1-7% in China). According to the report of the World Health Orga...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/48A61K38/39A61K9/16A61P9/12A61K35/56A61K35/614
Inventor 刘新张绵松袁文鹏夏雪奎张永刚贾爱荣孟秀梅王小军刘昌衡
Owner BIOLOGY INST OF SHANDONG ACAD OF SCI