A kind of assay method and equipment for platelet aggregation and coagulation factor

A technology of platelet aggregation and coagulation factors, applied in measuring devices, material analysis through optical means, instruments, etc., can solve the problems of prolonged test time, contamination of operators, and influence on the accuracy of test results, so as to avoid accuracy and improve Test the speed and protect the effect of health

Active Publication Date: 2011-11-30
BEIJING PRECIL INSTR CO LTD +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the test method of this patent has major defects. Only one blood sample can be measured at a time, which belongs to the category of manual measurement, which will not only prolong the test time, but also affect the accuracy of the test results due to manual negligence. Personnel contamination due to direct contact with patient blood samples

Method used

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  • A kind of assay method and equipment for platelet aggregation and coagulation factor
  • A kind of assay method and equipment for platelet aggregation and coagulation factor
  • A kind of assay method and equipment for platelet aggregation and coagulation factor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] see figure 1 , the assay method of platelet aggregation and coagulation factor of the present invention, uses a kind of automatic coagulation analyzer, described automatic coagulation analyzer comprises platelet aggregation testing device, blood coagulation testing device, sample plate device, reagent bottle device, cleaning tray device, delivery device for blood coagulation cup, blood aggregation sampling needle and cleaning needle device, coagulation blood sample needle and coagulation reagent needle device, and the blood aggregation sampling needle, blood coagulation sample needle and coagulation reagent needle are connected with automatic sampling pipeline , the cleaning needle is connected with the automatic cleaning pipeline. For the technical content of the automatic coagulation analyzer, please refer to the description of Example 3. The platelet aggregation is determined according to the photoelectric turbidimetry method, and the coagulation factors are determin...

Embodiment 2

[0076] see figure 2 , in this embodiment, the determination method of platelet aggregation and coagulation factor, uses a kind of automatic coagulation analyzer, and described automatic coagulation analyzer comprises platelet aggregation testing device, coagulation testing device, sample plate device, reagent bottle device , cleaning tray device, delivery device for blood coagulation cup, blood aggregation sampling needle and cleaning needle device, blood coagulation blood sample needle and blood coagulation reagent needle device, the blood aggregation sampling needle, blood coagulation blood sample needle and blood coagulation reagent needle are connected with automatic sample injection pipeline connection, and the cleaning needle is connected with the automatic cleaning pipeline. For the technical content of the automatic coagulation analyzer, refer to the description in Example 3. The coagulation factor is measured by the double magnetic circuit magnetic bead method, and t...

Embodiment 3

[0089] see image 3 , Figure 4 , Figure 5 , Figure 7 , Figure 9 , ( image 3 is when the analyzer front panel is removed), ( Figure 4 is the layout of the analyzer test bench), ( Figure 5 It is the situation that the side panel of the analyzer is removed), the automatic coagulation analyzer of the present invention has a support, and the support is provided with a photoelectric turbidimetry test circuit, a double magnetic circuit magnetic bead method test circuit, an automatic control circuit and Matching program, platelet aggregation test device 1, sample tray device 2, cleaning tray device 3, reagent bottle device 4, coagulation test device 5 are set on the test table 13 of the machine base; multiple A test cup 11 is provided with a detection optical system around the test cup, and the detection optical system includes a set of light-emitting transistor circuits and photoelectric conversion circuits; a magnetic stirring device is provided under the test cup. A p...

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Abstract

The invention relates to a method for measuring the platelet aggregation and a blood coagulation factor. In the method, a full-automatic coagulate blood analytical instrument is used, the platelet aggregation is measured by using photoelectric turbidimetry and the blood coagulation factor is measured by using a double magnetic circuit and bead method. The method comprises the following measuring steps of: preparing a platelet aggregation inductive agent, platelet rich plasma and platelet poor plasma; respectively reading light transmittance data of a platelet poor plasma sample and light transmittance data of a platelet rich plasma sample as well as light transmittance data of the platelet rich plasma during the forming process of the platelet aggregation within the specified time; calculating the platelet aggregation rate of the measured blood sample; absorbing the platelet poor plasma and injecting the platelet poor plasma in a hemagglutination cup; absorbing the selected reagent according to a test program and injecting the selected reagent into the hemagglutination cup; automatically monitoring the amplitude of a steel bead; and generating a test report by using measuring results of the platelet aggregation and the blood coagulation factor according to input information of patients.

Description

technical field [0001] The invention relates to a method and equipment for measuring platelet aggregation and coagulation factors. The method uses an automatic coagulation analyzer, platelet aggregation is measured according to photoelectric turbidimetry, and coagulation factors are measured according to a double magnetic circuit magnetic bead method , the automatic coagulation analyzer includes a platelet aggregation test device, a coagulation test device, a sample tray device, a reagent bottle device, a cleaning tray device, a delivery device for a blood coagulation cup, a blood aggregation sampling needle and a cleaning needle device, and a coagulation blood sample needle and a coagulation reagent needle device, the blood aggregation sampling needle, blood coagulation sample needle and coagulation reagent needle are connected to the automatic sampling pipeline, and the cleaning needle is connected to the automatic cleaning pipeline. Background technique [0002] Chinese p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/84
Inventor 肖继昌陈生朱宁平王怡董成刚王磊
Owner BEIJING PRECIL INSTR CO LTD
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