Composition for treating skin itch

A technology for skin itching and composition, applied in the field of compositions for treating skin itching, to achieve the effects of reducing scratching and skin itching

Inactive Publication Date: 2012-01-04
梁喆 +4
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Preferably dry until loss on drying < 3%

Method used

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  • Composition for treating skin itch
  • Composition for treating skin itch
  • Composition for treating skin itch

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Raw material pretreatment:

[0023] a. Dry and activate the clinoptilolite at 200°C, dry grind it into powder, and pass through a 200-mesh sieve;

[0024] b. Naturally dry the borneol until the weight loss on drying is less than 3%, pass through a 100-mesh sieve after crushing, and set aside;

[0025] c. Dried Cortex Phellodendri at 100°C until the weight loss on drying was less than 3%, crushed and passed through a 100-mesh sieve for later use.

[0026] (2) Composition II for the treatment of pruritus without peripheral skin damage: mix the activated zeolite powder prepared in the above step (1a) with the borneol powder prepared in the step (1b) in a mass ratio of 99:1, and 100 mesh sieve.

[0027] (3) Composition III for the treatment of existing pruritus of skin damage: the zeolite part prepared in the above step (1a), the borneol powder prepared in the step (2b), and the cork powder prepared in the step (1c) according to the mass Mix evenly at a ratio of 89:1...

Embodiment 2

[0032] Embodiment 2. skin irritation test

[0033] In accordance with the relevant provisions of the Chinese Pharmacopoeia 2010 edition. We did relevant skin allergy and irritation tests on 100% activated zeolite powder (prepared in step 1a, labeled as sample I), composition II, composition III and bath (composition IV).

[0034] 1. Skin allergy test:

[0035] Experiment grouping, choose 30 guinea pigs, half male and half female. Randomly divided into 5 groups, 6 in each group. One group is blank control group, and the other four groups are sample I, composition II, composition III and composition IV respectively. Use scissors to remove 2 x 2 cm of hair on the back of the guinea pig, apply sample I, composition II, composition III and composition IV to the depilated area, cover with 2 x 2 cotton gauze, and fix it with adhesive tape. The control group was only covered with gauze. After 24 hours, the gauze was removed, and the residual test substance was wiped off with warm...

Embodiment 3

[0041] Embodiment 3. clinical use effect:

[0042] Sample I, Composition II, and Composition III prepared in Example 1 are all powders. When in use, spread them evenly on the itchy areas and gently rub them on the skin. Within 3 to 6 days, there will be no recurrence.

[0043]The composition IV prepared in Example 1, that is, the bath agent, before bathing, bathes the whole body or local parts with clean water, and after evenly applying the bath liquid, it is just like taking a bath, just wash it off.

[0044] Case 1: Zhao XX, 51 years old. Suffering from intractable pruritus for more than 3 years, especially in winter, after many outpatient treatments of traditional Chinese and Western medicine, the curative effect is not obvious. After short-term antipruritic, promptly recurrence. According to someone's introduction, after using the composition 1 prepared by us, after spraying it twice, it has been 2 years since then. No recurrence was seen.

[0045] Case 2: Zhang XX, 6...

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Abstract

The invention relates to a composition for treating skin itch. The composition contains activated zeolite powder. According to the present invention, hundreds of patients use the composition provided by the present invention, the use results show that: the composition provides exact itching relieving effects for the skin itches caused by a plurality of skin diseases and unknown causes; because the skin itch of the patients is reduced, the scratching of the patients is reduced, such that the skin lesions caused by the scratching can be significantly improved.

Description

technical field [0001] The invention relates to a composition with antipruritic function and its product, in particular to a medicinal composition for skin itching caused by various skin diseases and unexplained intractable skin pruritus. Background technique [0002] Pruritus (pruritus) is one of the common clinical skin diseases, especially in the elderly. It is characterized by pruritus, without primary lesions. Clinically, it can be divided into localized and systemic. Pruritus is a skin disease with conscious itching but no primary lesions clinically. Localized pruritus is common in the anus, genitals, or limbs, where there is only conscious itching in the local area, without rash. Over time, it can cause skin thickening and eczema-like changes. Intractable itching in the anal canal and around the anus is the main symptom of this disease. It is generally limited to the skin around the anus at the beginning, mostly paroxysmal, and the degree of itching varies. If it d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K36/756A61K8/97A61K8/26A61Q19/10A61P17/04A61K31/045
Inventor 梁喆刘兆启刘佳梁捷梁强
Owner 梁喆
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