The invention discloses a bee venom compound with a sun-proof effect. The bee venom compound comprises a sun-proof cosmetic substrate component and bee venom. According to the invention, the bee venom is applied to sun-proof cosmetics for the first time, can effectively prevent ultraviolet ray from hurting skin, relieve scytitis caused by sunburn, and meanwhile enable the skin to keep humidification, provide nutrient for the skin, prompt the rehabilitation of hurt skin, and improve the self-protecting ability of the skin. And in addition, according to the invention, the bee venom, algal polysaccharides and Vc phosphate magnesium are compounded, thus the effects (including sun resistance, diminish inflammation, repair after being exposed to the sun and the like) of the bee venom compound are enhanced. The bee venom compound with the sun-proof effect comprises cream, emulsion, water aqua, gelatum and jelly, and is suitable for crowd with various skin types.