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Traditional Chinese medicine composition for treating kidney-yin deficiency and phlegm-blood stasis polycystic ovary syndrome (PCOS)

A technology for polycystic ovaries with phlegm and blood stasis, applied in drug combinations, pharmaceutical formulas, plant raw materials, etc., can solve problems such as low pregnancy rate, ovarian damage, pelvic adhesions, etc., achieve growth and development improvement, increase ovulation rate and Pregnancy rate, effect of reducing androgen level

Inactive Publication Date: 2012-01-04
上海泰坤堂中医医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs not only cannot effectively treat all PCOS, but also have defects such as low pregnancy rate and high miscarriage rate
Surgical puncture techniques are also used in the treatment of PCOS, which may cause damage to the ovaries, or cause pelvic adhesions and potential harm to the fetus

Method used

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  • Traditional Chinese medicine composition for treating kidney-yin deficiency and phlegm-blood stasis polycystic ovary syndrome (PCOS)
  • Traditional Chinese medicine composition for treating kidney-yin deficiency and phlegm-blood stasis polycystic ovary syndrome (PCOS)
  • Traditional Chinese medicine composition for treating kidney-yin deficiency and phlegm-blood stasis polycystic ovary syndrome (PCOS)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1 Preparation of decoction

[0039] Take 15g Anemarrhena, Fritillaria 12, Shouwu 24g, Ophiopogon 12g, Turtle shell 12g, Hippocampus 0.6g, Angelica 9g, Saponaria spp 15g and Acorus calamus 15g, rinse with water and soak in a container for more than 2 hours, then use The traditional decocting technique of decoction first and then down, decoction under normal pressure for 20 minutes to filter out the liquid medicine.

Embodiment 2

[0040] Example 2 Preparation of ointment

[0041] Take 150g Anemarrhena, Fritillaria 120, Shouwu 260g, Ophiopogon 120g, Tortoise shell 120g, Hippocampus 6g, Angelica 90g, Saponaria spp 150g and Acorus calamus 150g, rinse with water and soak in the container for more than 2 hours, then use the first The traditional decoction process after decocting and decoction. After decoction at normal pressure, the liquid is filtered out and concentrated under reduced pressure. During the liquid concentration, sugars and necessary auxiliary materials such as rock sugar, caramel and rice wine are added and stirred Collect ointment.

Embodiment 3

[0042] Example 3 Clinical observation

[0043] The enrollment of patients with kidney-yin deficiency and phlegm and blood stasis is based on the following criteria:

[0044] A) Western medicine diagnostic criteria: 1) Menstrual cramps for more than 2 years are still anovulatory menstruation (BBT monophasic), oligomenorrhea or amenorrhea; 2) Increased blood androgen: On the third day of uterine bleeding, blood testosterone (T) rises High or testosterone / estradiol log ratio (Log(T / E 2 ))>0.97; can be combined with 17α-hydroxyprogesterone (17α-OHP) and androstenedione increase; 3) B-ultrasound examination found that the ovarian volume increased (≥6ml), the number of follicles with a diameter of 2-9mm on a plane in the cortex >10.

[0045] B) TCM syndrome classification criteria: Except for low volume or amenorrhea in late menstrual period, infertility, accompanied by dry mouth, upset, internal heat, less entrainment, constipation, etc., dark red tongue, less moss, and thin pulse.

[004...

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating kidney-yin deficiency and phlegm-blood stasis polycystic ovary syndrome (PCOS). The traditional Chinese medicine composition comprises the medicinal materials such as anemarrhena, fritillary bulb, tortoise plastron, radix polygoni multiflori preparata, lilyturf root, hippocampus and the like. The medicinal materials are cooperative with each other so as to realize the efficacies of nourishing kidney and clearing away heat and reducing phlegm and removing blood stasis. The traditional Chinese medicine composition has the advantages of reducing the level of androgens and androgen receptors of patients suffering from PCOS, improving the level of sex hormone-binding globulin (SHBG), lowering the level of free testosterone (F-TESTO), further raising the level of in-vivo estrogens, improving growth and development of follicles and increasing ovulation rate and pregnancy rate of the patients.

Description

Technical field [0001] The present invention relates to a traditional Chinese medicine composition for the treatment of polycystic ovary syndrome, and in particular to a traditional Chinese medicinal composition which is made up of a variety of Chinese medicinal materials according to the emperor, minister, adjuvant and so on. Chinese medicinal composition for nodular polycystic ovary syndrome. Background technique [0002] Polycystic Ovary Syndrome (PCOS) was proposed by Stein and Leventhal in 1935. It refers to menstrual disorders, amenorrhea, anovulation, hirsutism, obesity, infertility and bilateral ovarian enlargement with polycystic changes, etc. The performance of a type of disease. This disease is a common endocrine disease in women and mostly causes reproductive disorders, and its incidence accounts for 5%-10% of women of childbearing age. Research in recent years has widely recognized that women with PCOS have varying degrees of insulin resistance, and that insulin re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K36/8945A61K36/90A61K36/9066A61K36/902A61K36/899A61K36/9064A61P15/00A61K35/56A61K35/586A61K35/60
Inventor 俞谨潘芳武大圣
Owner 上海泰坤堂中医医院有限公司
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