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Combined drug for treating upper gastrointestinal tract ulcer

A peptic ulcer and drug technology, applied in the field of medicine, can solve the problems of single anti-inflammatory, analgesic, aggravating the disease, losing confidence in life, etc., and achieves the effect of significant curative effect, alleviating abdominal distension, and regulating gastrointestinal function.

Inactive Publication Date: 2012-02-15
牛菊萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pattern is pain→eating→relief. About half of the patients have pain at midnight, and patients often wake up with pain. Acid reflux, heartburn, vomiting, etc. Vomiting and nausea mostly reflect that the ulcer has a high degree of activity, but it cannot be cured repeatedly, resulting in perforation, bleeding, and even cancer. , in the vicious circle of disease caused by poverty, the traditional treatment method is a single drug to relieve inflammation, pain, and acid temporarily, but it cannot cure
After taking one medicine for a long time, the symptoms improved for a while, and then relapsed, causing the patient to be extremely troubled, sad, and even aggravated, and lost confidence in life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] One plate of double aluminum blister pack contains 7 esomeprazole tablets, each tablet contains esomeprazole 20mg, one plate of aluminum-plastic plate packs trimebutine maleate contains 12 capsules, each tablet contains horse Trimebutine toate 100 mg, packed in an aluminum-plastic plate, bismuth pectin, containing 12 capsules, each containing bismuth pectin 50 mg, packed in an aluminum-plastic plate, containing 10 clarithromycin tablets, each containing Clarithromycin 0.25g, placed in the same package, used in combination according to the instructions.

Embodiment 2

[0031] One plate of double aluminum blister pack contains 14 esomeprazole tablets, each tablet contains esomeprazole 40mg, one plate of aluminum-plastic plate packs trimebutine maleate contains 12 capsules, each tablet contains horse Trimebutine toate 100 mg, packed in an aluminum-plastic plate, bismuth pectin, containing 12 capsules, each containing bismuth pectin 50 mg, packed in an aluminum-plastic plate, containing 10 clarithromycin tablets, each containing Clarithromycin 0.5g, placed in the same package, used in combination according to the instructions.

Embodiment 3

[0033] One plate of double aluminum blister pack contains 7 esomeprazole tablets, each tablet contains esomeprazole 40mg, one plate of aluminum-plastic plate packs trimebutine maleate contains 12 capsules, each tablet contains horse Trimebutine toate 100 mg, packaged on an aluminum-plastic plate, containing 12 capsules of bismuth pectin, each containing 50 mg of bismuth pectin, packaged on an aluminum-plastic plate, containing 8 capsules of clarithromycin, each containing Clarithromycin 0.125g, placed in the same package, used in combination according to the instructions.

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PUM

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Abstract

The invention provides application of esomeprazole and trimebutine maleate, bismuth pectin as well as clarithromycin in a combined drug for treating upper gastrointestinal tract ulcer, and simultaneously provides the combined drug of esomeprazole and trimebutine maleate, bismuth pectin as well as clarithromycin. The components of the combined drug preparation provided by the invention are matchedwith each other and exert actions from different angles, and has better treatment effect on upper gastrointestinal tract ulcer.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a combined medicine. Background technique [0002] Upper gastrointestinal ulcers mainly refer to chronic diseases that occur in the stomach and duodenum, and can also occur in the lower esophagus, around the gastrojejunostomy and MECKEL with ectopic gastric mucosa. The formation of these ulcers is related to gastric acid It is related to the digestion of pepsin, so it is called "peptic ulcer". In recent years, it has been found that the formation of ulcer disease is related to the presence of Helicobacter pylori (HP). The vast majority (more than 95%) of the disease is located in the stomach and duodenum, so it is also called gastroduodenal ulcer. The total incidence of the disease accounts for 5-10% of the population. Duodenal ulcer is more common than gastric ulcer. It is more common in young adults, more men than women, and children can also develop the disease. The proportion of ...

Claims

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Application Information

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IPC IPC(8): A61K31/732A61K31/7048A61K31/4439A61K31/24A61P1/04
Inventor 牛菊萍
Owner 牛菊萍
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