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Medicine composition for treating lower limb venous thrombosis

A technology of venous thrombosis and composition, applied in the field of traditional Chinese medicine, can solve the problems of patients with difficulties, slow recovery, high cost, etc.

Inactive Publication Date: 2012-06-27
赵玉山
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The current method of treating lower extremity venous thrombosis mainly adopts surgical treatment, but the recovery is relatively slow, the cost is high, and it is easy to leave sequelae
Although there are many kinds of drugs for treating lower extremity venous thrombosis, the effect is not very obvious, the treatment cycle is long, and the fees are high, which brings many difficulties and pains to patients and families.

Method used

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  • Medicine composition for treating lower limb venous thrombosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A traditional Chinese medicine composition for treating venous thrombosis of lower extremities, which is prepared from the following raw materials in weight ratio: Rhizoma Chuanxiong 23, Ginseng 20, Angelica 16, Earthworm 16, Fructus Lycii 14, Safflower 13, Chrysanthemum 11, Pangolin 10, Amomum 10, Astragalus 8, Divine Comedy 6, Chishao 6, Caulis Spatholobus 5, Achyranthes bidentata 4, Shenjincao 4, Chenpi 3.

[0017] The raw materials are made into powders according to conventional methods, passed through 80-mesh sieve, weighed in proportion, stirred and mixed, dried at 60°C for 1 hour, sterilized by ultraviolet light for 30 minutes, and finally loaded into capsules.

Embodiment 2

[0019] Clinical trial data:

[0020] Select 80 cases of venous thrombosis, take five capsules each time, two weeks as a course of treatment, take 4 courses of treatment, of which 71 cases were cured, accounting for 89%, 8 cases were effective, accounting for 10%, 1 case was ineffective, the total effective rate was 99% .

[0021] Efficacy evaluation criteria:

[0022] Cured: Limb pain, swelling, distended superficial veins and palpable cords along the veins and other clinical symptoms and signs disappeared, and the functional activities of sitting, standing and walking returned to normal, and all the indicators returned to normal after inspection.

[0023] Effective: The clinical symptoms such as limb pain, swelling, distended superficial veins and palpable cords along the veins have improved significantly or improved, and the examination indicators have slightly improved.

[0024] Ineffective: Limb pain, swelling, distension of superficial veins and palpable cords along the...

Embodiment 3

[0029] Typical cases:

[0030] (1) Liu, male, 51 years old, works in deep water, with swelling and pain in the left lower extremity, and palpable cords along the veins. Clinical diagnosis: X-ray venography is used to diagnose lower extremity venous thrombosis, sluggish venous blood flow, venous wall damage and hypercoagulable state of blood. Fibrinogen and D-dimer also have a significant increase. After taking medicine of the present invention for four courses of treatment, clinical symptoms and signs such as swelling and pain of lower limbs, palpable cords and strips of veins disappear, and the venous blood flow is smooth and smooth after inspection, and all indicators return to normal.

[0031] (2) Zhang XX, female, 36 years old. Clinical diagnosis: right lower extremity pain, swelling, superficial vein engorgement and palpable cord strips along the vein, shortened prothrombin time and activated partial thromboplastin time, and significant increases in fibrinogen and D-dime...

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Abstract

The invention relates to a medicine composition for treating lower limb venous thrombosis, which is prepared by the following raw materials with the weight ratio: ligusticum wallichii, ginseng, angelica sinensis, lumbricus, the fruit of Chinese wolfberry, red flower, chrysanthemum, manis pentadactyla, fructus amomi, astragalus mongholicus, medicated leaven, radix paeoniae rubrathe, caulis spatholobi, radix achyranthis bidentatae, lycopodium clavatum and pericarpium citri reticulatae. According to clinical verification, the medicine composition treats 80 venous thrombosis cases of illness, 71 cases are healed and account for 89% of the total cases, 8 cases are effective and account for 10% of the total cases, one case is ineffective, and the total effective rate is 99%. Medicine raw materials of the medicine composition for treating the lower limb venous thrombosis have low price, the medicine composition has wide market prospect and is free of toxic and side effects, and the preparation is simple and feasible.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating lower extremity venous thrombosis. Background technique [0002] Venous thrombosis refers to a disease in which acute non-suppurative inflammation occurs in veins and secondary thrombosis occurs under the conditions of sluggish venous blood flow, blood hypercoagulability, and vascular intima injury. The vast majority of venous thrombosis occurs in the deep veins of the pelvis and lower extremities. It is more common in postpartum, fracture and trauma, and postoperative patients. If limb pain, swelling, and palpable cords along the veins appear, the possibility of this disease should be considered. Ultrasound Doppler, radionuclide venography can help diagnosis. Thrombosis is easy to fall off in the early stage, which can cause large pulmonary infarction and is often one of the causes of sudden death. [0003] Venous thrombos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P7/02A61P9/00A61K35/36A61K35/64A61K35/62
Inventor 马庆亮孙振国
Owner 赵玉山
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