Blood-clearing dropping pills and preparation method thereof

A technology for clearing dripping pills and active ingredients, applied in the field of Xuebiqing dripping pills and their preparation, can solve the problems of difficulty in achieving the therapeutic effect of injections, low bioavailability, etc. handy effect

Inactive Publication Date: 2012-07-18
张睿
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Since traditional Chinese medicine injections are directly injected into the human body or veins, their safety is increasingly concerned, and clinically there are reports of some toxic and side effects or allergic reactions caused by Xuebiqing injections, and the injections are prepared into some conventional oral preparations such as oral Liquids, tablets, capsules, etc. have low bioavailability and are difficult to achieve the therapeutic effect of injections.

Method used

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  • Blood-clearing dropping pills and preparation method thereof
  • Blood-clearing dropping pills and preparation method thereof
  • Blood-clearing dropping pills and preparation method thereof

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Embodiment 1

[0026] Extraction method of active ingredients:

[0027] Wherein the weight of each component is as follows: 1000g of safflower, 1000g of red peony, 1000g of Chuanxiong, 1000g of salvia miltiorrhiza and 1000g of angelica.

[0028] Its preparation process is:

[0029] Safflower extraction process: put safflower in a container, wet it with 30% ethanol for 6 hours, put it into a percolation cylinder, soak it according to the Chinese Pharmacopoeia percolation method, and collect the percolation liquid as a medicine amount of 4-5 When the volume is doubled, stop receiving; add 95% ethanol to the percolation liquid to make the alcohol content 70%, after refrigerated and standing for 48 hours, filter, and the filtrate decompresses to recover the ethanol to the utmost, and concentrates to the equal volume of the medicinal material. Add 95% ethanol to make the alcohol content to 80%. After refrigerating and standing for 48 hours, filter the clear medicinal liquid, recover the ethanol ...

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Abstract

The invention belongs to the technical field of a medicinal preparation, in particular to blood-clearing dropping pills and a preparation method thereof. In the blood-clearing dropping pills with quick disintegration and high bioavailability, mixed substrate is adopted, and preferably mixed substrate consisting of polyethylene glycol and one of poloxamer, sodium stearate and gelatin glycerin at a weight ratio of 1-5:1, and the ratio of the medicinal active component to the substrate is preferably 1:(3-5).

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a Xuebiqing dripping pill and a preparation method thereof. Background technique [0002] Xuebiqing Injection is prepared from safflower, red peony, Chuanxiong, Danshen, and angelica. It has the functions of promoting blood circulation and removing blood stasis, dredging meridians, dispelling toxins, antagonizing endotoxin and inhibiting endogenous inflammatory mediators (TNFα) Runaway release. Indications: due to respiratory diseases such as acute suppurative tonsillitis, suppurative bronchitis, bronchiolitis and pneumonia such as Klebsiella, Pseudomonas, Pseudomonas aeruginosa; urinary system diseases such as pyelonephritis, cystitis, urethritis, etc.; Intra-abdominal infection: systemic inflammatory response syndrome caused by suppurative cholecystitis, cholangitis, suppurative peritonitis and other infections, the TCM syndrome is the syndrome of mutual accumula...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K9/20A61K47/34A61P31/04A61P43/00
Inventor 张睿
Owner 张睿
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