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Denture cleaning tablet

A technology for cleaning tablets and dentures, applied in the field of oral cavity, can solve problems such as easy adhesion of bacteria, formation of stones, and influence on oral hygiene of patients wearing dentures, and achieve excellent descaling and sterilization effects

Inactive Publication Date: 2013-06-05
JIANGSU BAIJIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Dentures are more likely to adhere to bacteria than real teeth, deposit dirt, pigment, and form stones, which seriously affect the oral hygiene of patients wearing dentures

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Example 1: Preparation of Dispersible Tablets of the Present Invention

[0010] Weigh 40 grams of honeysuckle, 100 grams of Cnidium, 20 grams of Forsythia, 50 grams of Schisandra, 20 grams of Perrin, 40 grams of Eucommia, 70 grams of purslane, 40 grams of Cnidium and 800 milliliters of water, and placed in a sealed flask . Heat in a water bath at 90°C for 3 hours, filter, collect the filtrate, and concentrate to dryness. Pulverize, pass through an 80-mesh sieve, add 20 grams of microcrystalline cellulose, 10 grams of croscarmellose sodium, 20 grams of lactose, and 3 grams of magnesium stearate, mix well, and directly press the powder into 100 pieces. .

experiment example 1

[0011] Experimental Example 1 Detergency test

[0012] Take two dispersible tablets prepared in Example 1, put them in 100 ml of water, and within 3 minutes, the dispersible tablets completely disintegrated. Stir well with a glass rod and let stand for a clear cleaning solution.

[0013] Grading standard of denture dirtyness: grade I, scattered tea stains, smoke stains and dirt can be seen in a certain part of the denture; grade II, there are lumps of smoke, tea, dirt or calculus in each part of the denture; grade III, all parts of the denture Large pieces or entire dentures had smoke, tea, dirt, or calculus.

[0014] Fifty dentures with smoke and tea stains, dirt and calculi were collected, scrubbed with tap water and then graded for dirtiness, including 16 cases of grade I, 12 cases of grade II, and 22 cases of grade III. Then soak them in the cleaning solution for 2 hours, take them out and scrub with a cotton swab to observe the decontamination effect.

[0015] The eval...

experiment example 2

[0017] Experimental Example 2 Sterilization test

[0018] Take two dispersible tablets prepared in Example 1, put them in 100 ml of water, and within 3 minutes, the dispersible tablets completely disintegrated. Stir well with a glass rod and let stand for a clear cleaning solution.

[0019] Collect 10 dentures, immerse them in sterile saline for 1 hour, wash the bacteria on the dentures, and dilute them with saline to 10 3 / ml bacterial suspension. take 10 3 0.01ml / ml of bacterial suspension was inoculated into dish agar medium, placed in a 37°C incubator for 24h, identified as common oral normal bacteria, mixed bacterial suspension and cleaning solution 1:1 (volume) for 30min, respectively took out 0.01 ml was streaked in the dish medium, and it was found that the bacteria suspension and the cleaning solution were mixed 1:1 within 30 minutes to kill the bacteria, and sterile plaques were formed.

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PUM

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Abstract

The invention relates to a denture cleaning tablet, which consists of the following substances in part by weight: 3 to 5 parts of honeysuckle flowers, 5 to 15 parts of Chinese violet, 1 to 5 parts of forsythia, 4 to 8 parts of shizandra berry, 1 to 5 parts of eupatorium, 3 to 7 parts of cortex eucommiae, 5 to 11 parts of purslane, 3 to 5 parts of frutus cnidii and carriers being acceptable on themedical. The denture cleaning tablet has an excellent effect on decontamination and sterilization and can be widely applied to the clinical.

Description

technical field [0001] The invention relates to the field of oral cavity, in particular to a denture cleaning sheet. Background technique [0002] Dentures are more likely to adhere to bacteria than real teeth, deposit dirt, pigment, and form calculus, which seriously affects the oral hygiene of patients wearing dentures. It is reported that about 65% of patients who wear full or partial dentures suffer from denture stomatitis, which is caused by trauma to the oral mucosa caused by unclean dentures, especially Candida albicans. SUMMARY OF THE INVENTION [0003] The object of the present invention is to provide a denture cleaning sheet. [0004] In order to achieve the purpose of the present invention, the present invention provides a kind of denture cleaning sheet, which is made of the following substances by weight ratio: 3-5 parts of honeysuckle, 5-15 parts of Viola vulgaris, 1-5 parts of Forsythia suspensa, 4-8 parts of Schisandra, 1-5 parts of Perrin, 3-7 parts of Eu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/97A61Q11/02
Inventor 王战芝
Owner JIANGSU BAIJIAN PHARMA TECH CO LTD