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A kind of traditional Chinese medicine composition for treating lupus erythematosus

A technology for lupus erythematosus and a composition, which is applied in the field of traditional Chinese medicine compositions, can solve the problems of high price, large prescription, unsuitable for long-term use and the like, and achieves the effects of low cost, resource saving and good social benefits

Active Publication Date: 2015-10-28
NAT ENG RES CENT FOR TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, through investigation, there are very few Chinese patent medicines with national approval numbers on the market. Most of them are adjuvant treatments, and there are large prescriptions, high prices, animal medicines or toxic medicinal materials, and they are not suitable for long-term use.

Method used

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  • A kind of traditional Chinese medicine composition for treating lupus erythematosus
  • A kind of traditional Chinese medicine composition for treating lupus erythematosus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Weigh raw materials: Rehmannia 15g, Lonicerae 15g, Gypsum 15g, Sophora flavescens 15g, Scutellaria baicalensis 15g

[0020] Decocting and extracting the above-mentioned crude drug twice with water, the amount of water added for the first extraction is 15 times of the amount of medicine, and the extraction time is 3 hours; the amount of water added for the second extraction is 10 times of the amount of medicine, and the extraction time is 3 hours; Add ethanol for alcohol precipitation, adjust the alcohol content to 30%, filter, and concentrate the alcohol precipitation solution; use vacuum drying to dry, and the vacuum drying temperature is controlled at 50°C; after drying, the water content of the medicinal extract is controlled below 5%; Add an appropriate amount of auxiliary materials micropowder silica gel, dextrin, and starch; mix the above materials, adopt wet granulation, dry, fill the granules after granulation, and pack them into bags, each bag contains 8 grams. ...

Embodiment 2

[0023] Weigh raw materials: Rehmannia 15g, Lonicera vine 15g, Gypsum 15g, Sophora flavescens 2.5g, Scutellaria baicalensis 2.5g

[0024] Decocting and extracting the above-mentioned crude drug twice with water, the amount of water added for the first extraction is 6 times of the amount of medicine, and the extraction time is 0.5 hour; the amount of water added for the second extraction is 4 times of the amount of medicine, and the extraction time is 0.5 hour; Filtrate, combine the filtrates, and concentrate; use spray drying to dry, and spray drying is to concentrate the medicinal solution to 1.1g / ml (60°C thermal measurement), the inlet air temperature is controlled at 150°C, and the outlet air temperature is controlled at 80°C; After drying, the water content of the medicinal extract is controlled below 5%; add appropriate amount of auxiliary materials micro-powdered silica gel and dextrin to the medicinal extract; mix the above materials, use wet granulation, dry, and fill c...

Embodiment 3

[0026] Weigh raw materials: Rehmannia 5g, Lonicerae 15g, Gypsum 15g, Sophora flavescens 10g, Scutellaria baicalensis 5g

[0027] Decoction and extraction of the above-mentioned crude drug twice with water, the first time the amount of water added is 10 times the amount of medicine, and the extraction time is 2 hours; the second time the amount of water added is 7 times the amount of medicine, and the extraction time is 2 hours; filter, Combine the filtrates and concentrate; use vacuum drying to dry, and the vacuum drying temperature is controlled at 70°C; after drying, the water content of the medicinal extract is controlled below 5%; add appropriate amount of auxiliary materials micropowder silica gel, starch, and microcrystalline cellulose to the medicinal extract; The above materials are mixed, granulated by wet method, dried, pressed into tablets after granulation, and made into tablets, each tablet is 0.5 g.

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating lupus erythematosus. The traditional Chinese medicinal composition is composed of a water extract or a water-extraction and alcohol-deposition substance of five crude medicines comprising 5-30 parts of unprepared rehmannia root, 5-30 parts of honeysuckle stem, 5-30 parts of gypsum, 5-20 parts of Sophora flavescens and 5-20 parts of Radix Scutellariae. A water extraction method or a water-extraction and alcohol-deposition method is adopted to obtain the extract to prepare a traditional Chinese medicinal oral preparation. The traditional Chinese medicinal composition can effectively treat the lupus erythematosus, and is very important for satisfying medical clinic demands and market demands.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating lupus erythematosus. Background technique [0002] Systemic lupus erythematosus (SLE) is an autoimmune chronic inflammatory connective tissue disease that involves multiple systems and organs, seriously affecting human health, and is a lifelong disease that requires lifelong medication. [0003] The etiology of lupus erythematosus is still not completely clear, and the factors related to its pathogenesis are now found to be: genetic factors, infection factors, endocrine factors, and environmental factors. [0004] The annual incidence of lupus erythematosus in the world is between 4 million and 5 million people. According to the preliminary epidemiological survey in my country, the prevalence rate is 70-100 / 100,000 people. At present, there are about 1 million patients. The number of people suffering from polluti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61P37/06A61P19/04A61K33/06
Inventor 汤秀珍姚譞杜晨捷樊敏伟
Owner NAT ENG RES CENT FOR TRADITIONAL CHINESE MEDICINE
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