Preparation method of plant-based slow-release compound antibacterial agent for prevention and control of skin ulcer syndrome of Apostichopus japonicus
A compound antibacterial agent, rot skin syndrome technology, applied in the fields of plant/algae/fungus/moss ingredients, antibacterial drugs, plant raw materials, etc. problems, to achieve the effect of promoting food digestion, reducing the amount of drug use, and not producing drug resistance
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[0022] Using Shewanella yellow sea, a common pathogenic bacterium of A. japonicus rotting skin syndrome in the north, as the model test bacteria, 40 kinds of Chinese herbal medicines derived from plants were screened, and the size of the antibacterial zone was determined; Chinese herbal medicines with good antibacterial effects were selected for the minimum inhibitory concentration test; Composite, then do the orthogonal test; choose the best compound, do the minimum inhibitory concentration test, use the compound to carry out the minimum inhibitory concentration test on other reported A. japonicus rotting skin syndrome pathogens; Toxic reactions; final clinical treatment verification.
[0023] 1. Antibacterial experiment of botanical Chinese herbal medicine
[0024] 1. Preparation of model strains for testing. Shewanella yellowsea is the main pathogen causing rotting skin syndrome of Apostichopus japonicus in the northern coast, provided by the Aquatic Animal Disease Laborat...
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