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Application of ginkgolic acid in weight losing

A technology of ginkgolic acid and ginkgolic acid, which is applied in the directions of medical raw materials, cosmetic preparations, and skin care preparations derived from Ginkgo biloba, can solve the problems of human health damage, large toxic and side effects, etc. , the effect of reducing quantity and volume

Inactive Publication Date: 2013-01-02
王青
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some weight loss products on the market contain chemicals with high toxic and side effects, which have caused serious damage to human health; therefore, the market needs to develop weight loss cosmeceuticals that come from natural sources, have significant effects, and are safe to use, so as to meet people's pursuit of beauty and Treatment needs; the development of such products has a good market prospect and is very beneficial and necessary
There is no report on the use of ginkgolic acid in weight loss

Method used

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  • Application of ginkgolic acid in weight losing
  • Application of ginkgolic acid in weight losing
  • Application of ginkgolic acid in weight losing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The extraction process of ginkgolic acid from the ginkgo fruit outer testa is as follows: the ginkgo fruit outer testa is peeled off, dried in the sun, and pulverized with a pulverizer. Accurately weigh a certain amount of crushed ginkgo testa, add 80% ethanol with a material-to-liquid ratio of 1:6 (W / V), stir and extract twice at a water bath temperature of 60°C, and extract for 4 hours each time , (Note: After adding liquid, seal the mouth of the beaker with plastic wrap to prevent the volatilization of ethanol). After the leaching is finished, filter with a suction filter to collect the filtrate. Concentrate the filtrate with a vacuum rotary evaporator at a temperature of 55° C. and a pressure of 0.008-0.009 MPa, and concentrate under reduced pressure. Vacuum-dried at 60°C to obtain ginkgolic acid extract. The properties are: light brown extract, slightly smelly, soluble in alcohol, insoluble in water; weighed, and determined the content of ginkgolic acid (mg / g).

...

Embodiment 2

[0025] The extraction process of ginkgo phenolic acid from ginkgo fruit ginkgo is as follows: peel the ginkgo fruit, put it into a tissue grinder, and pulverize it. Accurately weigh a certain amount of pulverized Ginkgo fruit, add 80% ethanol with a solid-liquid ratio of 1:10 (W / V), and stir and extract twice at a water bath temperature of 60° C., each extraction time is 4 hours, (Note : After adding liquid, the mouth of the beaker is sealed with plastic wrap to prevent the volatilization of ethanol). After leaching finishes, centrifuge (5000 rpm, 15 minutes), get supernatant. Concentrate the supernatant with a vacuum rotary evaporator under the conditions of temperature 55°C, pressure 0.008-0.009MPa, concentrate under reduced pressure, and vacuum-dry at 60°C to obtain ginkgolic acid extract, which has the following properties: light brown extract, slightly odorous , Soluble in alcohol, insoluble in water. Weigh and determine the content of ginkgolic acid (mg / g).

[0026] G...

Embodiment 3

[0030] The extraction process of ginkgophenolic acid in ginkgo leaves is as follows: cut the ginkgo leaves into pieces, put them into a pulverizer and pulverize them. Accurately take a certain amount of crushed Ginkgo biloba, add 80% ethanol with a solid-liquid ratio of 1:6 (W / V), and stir and extract 2 times at a water bath temperature of 60° C., each extraction time is 4 hours, ( Note: After adding liquid, seal the mouth of the beaker with plastic wrap to prevent the volatilization of ethanol). After leaching finishes, centrifuge (5000 rpm, 15 minutes), get supernatant. Concentrate the supernatant with a vacuum rotary evaporator under the conditions of temperature 55°C, pressure 0.008-0.009MPa, concentrate under reduced pressure, and vacuum-dry at 60°C to obtain ginkgolic acid extract, which has the following properties: light brown extract, slightly odorous , Soluble in alcohol, insoluble in water. Weigh and determine the content of ginkgolic acid (mg / g).

[0031] Ginkgo...

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Abstract

The invention relates to application of ginkgolic acid in weight losing. The ginkgolic acid comprises ginkgolic acid, ginkgol and bilobol and can be obtained from extracts of such parts of the gingko as leaves, fruits, testae and rootstalks by a chemical separation method. A weight reducing medicament or cosmetic contains 0.001-80% of ginkgolic acid by weight percent and pharmaceutically common external preparation substrates or acceptable carriers. The preparation is any one pharmaceutically called external dosage form. Pharmacological experiment studies show that the preparation has the functions of reducing weight, body fat and adipocyte quantity and volume and has the effect of reducing blood sugar and blood fat. Trial results of fat people show that the preparation has the functions of reducing weight and removing fat, is obvious in weight reducing effect, is safe to use and has no effects.

Description

technical field [0001] The invention belongs to the fields of biomedicine and cosmeceuticals, and in particular relates to the use of ginkgolic acid in weight loss. Background technique [0002] Obesity not only brings people an indecent appearance, but also often causes symptoms such as fatigue, shortness of breath, and palpitations, which not only affects people's quality of life, but also causes a variety of diseases, seriously threatening human health. Therefore, the prevention and treatment of obesity has increasingly attracted people's attention, and weight loss has become one of the hot topics in the world. Finding safer and more effective new topical slimming products is one of the research hotspots in cosmeceuticals today. With the development of biochemical technology, people's understanding of the biological mechanism of obesity is deepening, and more and more researchers tend to look for safe and efficient weight loss active substances from natural plants. Some...

Claims

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Application Information

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IPC IPC(8): A61K36/16A61K31/60A61K31/05A61K8/97A61K8/368A61K8/34A61P3/04A61P3/06A61P3/10A61Q19/00
Inventor 雷红王青
Owner 王青
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