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Medicine composition as well as application and preparation of medicine composition

A technology of pharmaceutical preparations and compositions, applied in the fields of pharmaceutical compositions and their uses and preparations, which can solve the problems of skin irritation, easy-to-contaminate clothing, easy curling and shedding, etc.

Active Publication Date: 2014-03-19
北京卓越同舟药物研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, black plasters, ointments, and adhesive plasters have problems such as small drug loading, easy contamination of clothes, and irritation to the skin to varying degrees.
The cataplasm has a large amount of drug loading, but its elasticity and viscosity are poor, and it is easy to curl and fall off

Method used

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  • Medicine composition as well as application and preparation of medicine composition
  • Medicine composition as well as application and preparation of medicine composition
  • Medicine composition as well as application and preparation of medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0132] The medicinal composition is: chuanxiong 300g, notopterygium 300g, angelica 255g, cinnamon twig 155g, kudzu root 255g, safflower 150g, red peony 250g, eucommia 150g, clematis 255g, mulberry 155g, dog spine 100g, fennel 100g, Ben 105g, Gastrodia elata 150g, papaya 150g, Gentiana 150g, Salvia 305g, peach kernel 100g, Angelica dahurica 250g, Caulis Spatholobus 300g, borneol 50g.

[0133] (1) Extraction of extract: the above 21 flavors, except borneol, extract volatile oil from notopterygium and cumin, and reserve the volatile oil for later use; filter the extracted water, concentrate to a relative density of 1.13-1.15 (50°C), add ethanol so that the alcohol content is 70%, put it aside for 24 hours, filter, and set aside; extract the dregs with 70% ethanol twice, 10 times each time, extract for 2 hours, filter the extract, set aside; the remaining 18 herbs such as Chuanxiong, etc., use 70% ethanol Extract 3 times, 6 times each time, extract for 2 hours, filter the extract,...

Embodiment 2

[0137] The medicinal composition is: chuanxiong 395g, notopterygium 400g, angelica 295g, cinnamon twig 200g, kudzu root 295g, safflower 245g, red peony 300g, eucommia 250g, clematis 300g, mulberry 245g, dog spine 150g, fennel 145g, Ben 145g, Gastrodia elata 250g, papaya 245g, Gentiana 250g, Salvia miltiorrhiza 395g, peach kernel 145g, Angelica dahurica 300g, Miltonia 395g, borneol 100g.

[0138] (1) Extraction of extract: the above 21 flavors, except borneol, extract volatile oil from notopterygium and cumin, and reserve the volatile oil for later use; filter the extracted water, concentrate to a relative density of 1.13-1.15 (50°C), add ethanol so that the alcohol content is 70%, put it aside for 24 hours, filter, and set aside; extract the dregs with 70% ethanol twice, 10 times each time, extract for 2 hours, filter the extract, set aside; the remaining 18 herbs such as Chuanxiong, etc., use 70% ethanol Extract 3 times, 6 times each time, extract for 2 hours, filter the extr...

Embodiment 3

[0142] The composition of the pharmaceutical composition is: Chuanxiong 345g, Notopterygium 345g, Angelica 276g, Guizhi 207g, Pueraria 276g, Safflower 207g, Chishao 276g, Eucommia 207g, Clematis 276g, Sangjisheng 207g, Dogji 138g, Cumin 138g , Ligusticum 138g, Gastrodia elata 207g, papaya 207g, Gentiana 207g, Salvia 345g, peach kernel 138g, Angelica dahurica 276g, Caulis Spatholobus 345g, borneol 69g.

[0143] (1) Extraction of extract: the above 21 flavors, except borneol, extract volatile oil from notopterygium and cumin, and reserve the volatile oil for later use; filter the extracted water, concentrate to a relative density of 1.13-1.15 (50°C), add ethanol so that the alcohol content is 70%, put it aside for 24 hours, filter, and set aside; extract the dregs with 70% ethanol twice, 10 times each time, extract for 2 hours, filter the extract, set aside; the remaining 18 herbs such as Chuanxiong, etc., use 70% ethanol Extract 3 times, 6 times each time, extract for 2 hours, ...

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Abstract

The invention belongs to the technical field of medicines and provides a medicine composition as well as an application and a preparation of the medicine composition. The medicine composition is composed of ligusticum wallichii, notopterygium root, angelica sinensis, cassia twig, root of kudzu vine, red flower, root of common peony, eucommia ulmoides, radix clematidis, parasitic loranthus, rhizoma cibotii, fennel, ligusticum, gastrodia elata, pawpaw, large-leaved gentian, root of red-rooted salvia, peach kernel, radix angelicae, caulis spatholobi and borneol. Pharmacological tests and clinical tests indicate that the medicine composition has an effect of treating orthopedics diseases.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition and its application and preparation. Background technique [0002] Cervical spondylosis is the primary or secondary degeneration of cervical intervertebral discs, cervical vertebral bodies and their bone joints, cartilage, ligaments, muscles, fascia and other tissues, resulting in adjacent nerve roots, blood vessels (mainly It is vertebral artery), sympathetic nerve, spinal cord and other tissues are compressed, stimulated, destabilized and other damages, thus causing corresponding clinical symptoms and signs. Cervical spondylosis is also known as cervical syndrome. [0003] With the improvement of people's living standards and life expectancy, the incidence of cervical spondylosis is increasing day by day; coupled with the accelerated pace of modern life, the widespread use of air conditioners, long-term use of computers, long-term desk...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61P29/00A61P19/08A61P19/02
Inventor 周志欢谭洪全
Owner 北京卓越同舟药物研究院有限公司