Ramie total phenolic acid extract, its production method and use

A technology of total phenolic acid and extract, which is applied in the field of ramie total phenolic acid extract and can solve the problems such as no useful components to be extracted.

Inactive Publication Date: 2013-01-30
北京青山绿水苎麻制品有限公司 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are currently some patent applications or patents involving the use of ramie roots and other ramie plant parts as raw materials for the production of traditional Chinese medicines, there are no reports about extracting useful ingredients from ramie and preparing them into medicines

Method used

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  • Ramie total phenolic acid extract, its production method and use
  • Ramie total phenolic acid extract, its production method and use
  • Ramie total phenolic acid extract, its production method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0150] Example 1: Production of ramie total phenolic acid extract from ramie

[0151] a) Ethanol extraction

[0152] Weigh 100 g of dried ramie leaves, add 10 times (1 liter) of the weight of dried ramie leaves to the 95% ethanol aqueous solution by weight, then heat and reflux for 3 times, separate the ethanol extract, discard the residue, and combine The ethanol extract is then concentrated into extract by rotary evaporation at a temperature of 55°C, and the ethanol is recovered for recycling;

[0153] b) First ethyl acetate extraction

[0154] Add 150 mL of distilled water to the extract obtained in step a) to suspend the extract into a colloidal solution, and then extract the colloidal solution with ethyl acetate 3 times, 100 mL each time, combine the ethyl acetate extracts, and discard the extract Remaining liquid

[0155] c) Alkaline solution back extraction

[0156] Step b) Use Na with pH 11 for the ethyl acetate extract obtained 2 CO 3 The aqueous solution was back-extracted 3 ...

Embodiment 2~9

[0163] Example 2~9: Production of ramie total phenolic acid extract from ramie

[0164] Examples 2-9 were performed in the same manner as Example 1, except that some of the parameters were changed, and the remaining parameters were the same as Example 1. The variation parameters and measurement results of Examples 2-9 are also listed in Table 5.

[0165] Table 5: The determination results of the total phenolic acid extract of ramie prepared in Examples 1-9

[0166]

[0167] In the table:

[0168] A represents the weight percent concentration of ethanol aqueous solution;

[0169] B represents the pH value of the inorganic alkali aqueous solution;

[0170] C represents the weight ratio of inorganic alkali aqueous solution to ethyl acetate;

[0171] D stands for pH adjustment.

[0172] The following describes the biological experiment of the ramie total phenolic acid extract of the present invention.

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Abstract

The invention relates to a method for production of a ramie total phenolic acid extract from ramie leaves, and also relates to the ramie total phenolic acid extract obtained by the production method and use thereof. The method for production of the ramie total phenolic acid extract from ramie leaves comprises: ethanol extraction, first ethyl acetate extraction, alkaline solution back extraction, second ethyl acetate extraction, concentration and drying, and other steps. The ramie leaf extract process provided in the invention is simple and effective, and is suitable for industrial production, the yield of total phenolic acid crude extract is up to over 19%, and the polyphenol content is over 0.21wt%. The ramie total phenolic acid extract provided in the invention has inflammation resisting, pain alleviating, microcirculation and blood rheology improving and other functions, and has a good repairing effect on acute soft tissue injury.

Description

【Technical Field】 [0001] The invention relates to the technical field of Chinese medicine. More specifically, the present invention relates to a method for producing ramie total phenolic acid extract from ramie leaves, as well as to the ramie total phenolic acid extract obtained by the production method and their uses. 【Background technique】 [0002] Ramie, as the main raw material of my country's hemp textile industry and an important plant variety for soil and water conservation, has attracted great attention from all parties. The "Hua Lai 4", "Hua Lai Number 5" and "Xiang Lai Number 2" have been cultivated with excellent quality. The new variety of ramie has played an important role in farmers' enrichment, planting structure adjustment, employment increase, and ecological adjustment. [0003] Ramie (Boehm erianivea or Ramie) belongs to the ramie genus of the Urticaceae family. It is a peculiar crop in my country that uses textiles as its main purpose. It is a national treasure o...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P29/00A61K127/00
Inventor邰源临邹坤胡建忠汪鋆植李蓉周媛夏静芳杨进土小宁郭志勇蔡建勤陈剑锋闫培华温秀凤郭海殷丽强徐楠王丹刘朝奇程凡
Owner北京青山绿水苎麻制品有限公司