Traditional Chinese medicine composition for treating menopausal syndrome and preparation method thereof

A technology for menopausal syndrome and composition, which is applied in the preparation of the traditional Chinese medicine composition and the field of traditional Chinese medicine composition for treating menopausal syndrome, and can solve problems such as increasing the risk of female thrombotic disease and stroke

Inactive Publication Date: 2013-03-27
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in recent years, a number of large-scale clinical trials have reported that HT can increase women's risk of breast cancer, ovarian cancer, endometrial cancer, thrombotic disease, coronary heart diseas

Method used

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  • Traditional Chinese medicine composition for treating menopausal syndrome and preparation method thereof
  • Traditional Chinese medicine composition for treating menopausal syndrome and preparation method thereof
  • Traditional Chinese medicine composition for treating menopausal syndrome and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 Granules

[0019] Weigh raw materials: Shengdi 5g, Radix Paeoniae Alba 5g, Anemarrhena 5g, Phellodendron 5g, Morinda officinalis 5g, Lingpi 5g, raw oyster 15g, raw keel 15g, Bupleurum 5g, Caulis japonica 10g.

[0020] Take half of the medicine in the above formula, add 3 times the amount of water, soak for 1 hour, decoct for 1 hour, add 3 times the amount of water, decoct for 45 minutes, filter, combine the decoction, concentrate under reduced pressure, and dry under reduced pressure Extract, crushed into fine powder (over 80 mesh). The other half of the crude drug is crushed through 80 orders, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added mannitol, lactose, sucrose powder, aspartame, menthol, mixed evenly and used 60% ethanol as The binder is made into granules, packed in bags, 15 grams per bag, orally 2 times a day, 1 bag each time.

Embodiment 2

[0021] Embodiment 2 Granules

[0022] Weigh raw materials: Shengdi 60g, Radix Paeoniae Alba 40g, Anemarrhena 40g, Cortex Phellodendron 40g, Morinda officinalis 40g, Lingpi 60g, raw oyster 120g, raw keel 120g, Bupleurum 40g, Teng Yejiao 120g.

[0023] Take half of the medicine in the above formula, add 8 times the amount of water, soak for 1 hour, decoct for 1 hour, add 8 times the amount of water, decoct for 45 minutes, filter, combine the decoction, concentrate under reduced pressure, and dry under reduced pressure Extract, crushed into fine powder (over 80 mesh). The other half of the crude drug is crushed through 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added mannitol, lactose, sucrose powder, aspartame, menthol, mixed evenly and used 70% ethanol as The binder is made into granules, packed in bags, 15 grams per bag, orally 2 times a day, 1 bag each time.

Embodiment 3

[0024] Embodiment 3 granules

[0025] Weigh raw materials: Shengdi 7.5g, Radix Paeoniae Alba 5g, Anemarrhena 5g, Phellodendron 5g, Morinda officinalis 5g, Lingpi 7.5g, raw oyster 15g, raw keel 15g, Bupleurum 5g, Teng Yejiao 15g.

[0026] Take half of the amount of medicine in the above formula, add 5 times the amount of water, soak for 1 hour, decoct for 1 hour, add 5 times the amount of water, decoct for 45 minutes, filter, combine the decoction, concentrate under reduced pressure, and dry under reduced pressure Extract, crushed into fine powder (over 80 mesh). The other half of the crude drug is crushed to 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added mannitol, lactose, sucrose powder, aspartame, menthol, mixed evenly and used 65% ethanol as The binder is made into granules, packed in bags, 15 grams per bag, orally 2 times a day, 1 bag each time.

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Abstract

The invention belongs to the field of Chinese medicine pharmacy, and relates to a traditional Chinese medicine composition for treating menopausal syndrome and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises traditional Chinese medicine radix rehmanniae, radix paeoniae alba, rhizoma anemarrhenae, golden cypress, morinda officinalis, herba epimedii, raw oyster shell, crude dragon bone, radix bupleuri and tuber fleeceflower stem as main medicines, and is blended with auxiliary materials to be prepared into the preparation for treating the symptoms related to menopause, i.e. the heating, the sweating, the agitated emotion, the insomnia and the like. The experiment proves that the traditional Chinese medicine composition provided by the invention has the definite functions for improving the blood serum E2 and reducing the blood serum FSH (follicle-stimulating hormone), the hypothalamus estrogen receptors Er alpha, Er beta gene expression and protein expression can be continuously adjusted, and the situation of hypothalamus aging can be improved, so that the menopausal syndrome can be effectively cured.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating menopausal syndrome; in addition, the invention also relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] Menopausal syndrome has become a worldwide topic in the field of women's medical and health care due to its high incidence, the impact on women's quality of life, the occurrence of senile diseases, and the limitations of hormone replacement therapy. According to reports, the incidence of menopausal syndrome is as high as 85-90%, and 25% of women need medical treatment because they cannot bear it. Moreover, the duration of menopause syndrome has individual differences. Usually, menopause-related symptoms can last for 1-5 years, but 15% of patients have more than 15 years, and 9% of patients will still have symptoms of heat and sweating even a...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P15/12A61K35/56A61K35/02A61K35/618
Inventor 孙卓君徐莲薇桑珍
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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