Chinese veterinary drug preparation for preventing or curing poultry respiratory diseases

A technology for respiratory tract and diseases, which is applied in the field of veterinary drug preparations for preventing or treating infectious laryngotracheitis in chickens, and can solve the problems of high cost, slow absorption, infectious diseases and the like

Inactive Publication Date: 2014-04-09
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, in order to prevent the occurrence and prevalence of this disease, the method of vaccination is mostly used. However, due to antigenic variation, the emergence of super-virulent strains, improper selection of vaccine varieties, improper vaccination procedures, interference of maternal antibodies, environment and many other factors However, the disease still cannot be effectively controlled; the application of hyperimmune serum and egg yolk antibody to treat the disease has a good curative effect, but the cost is too high. Infectious diseases, so it is not a good way to now
However, after traditional antibiotic treatment, a large amount of antibiotic residues are produced, which threatens the health of human beings after long-term consumption.
Scholars at home and abroad have conducted research on the disease for many years, but so far have not found a relatively ideal and effective control measure

Method used

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  • Chinese veterinary drug preparation for preventing or curing poultry respiratory diseases
  • Chinese veterinary drug preparation for preventing or curing poultry respiratory diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0027] Example 1-3 Preparation of veterinary medicine oral liquid

[0028] Table 1 Example 1-3 The prescription of veterinary medicine oral liquid

[0029] Chinese herbal medicine Example 1 Example 2 Example 3 honeysuckle240g280g200g Houttuynia cordata240g200g280g Su Zi210g180g230g Ephedra200g230g200g Guizhi200g200g230g plaster150g180g120g Sampi150g120g180g Burdock100g80g120g Scutellaria 100g80g120g

[0030] Preparation Process:

[0031] (1) Take the above-mentioned Chinese medicinal materials in the prescribed amount, wash and remove impurities, dry, and crush into particles;

[0032] (2) Then add water to the above granular medicinal materials to spread over the medicinal surface for 2cm, soak for 1-1.2h, remove the medicinal materials and place them in a multifunctional extraction pot, add water and cook twice, add 10 times the amount of water to the medicinal materials for the first time, and decoct Cook for 2 hours, take the decoction, filter, add 8 times the amount ...

Embodiment 4

[0033] Example 4 The effect test of Chinese veterinary medicine oral liquid of the present invention on chicken infectious laryngotracheitis model

[0034] Take 10 SPF chicken embryos and culture them at 37℃. When the chicken embryos are cultured to the age of 10 days, the chorioallantoic membrane is inoculated with ILTV standard virus. The eggs are taken daily to observe the development of the chicken embryos, and the embryos that die within 24 hours are discarded After 72 hours, dead and undead chicken embryos were collected, and the diseased allantoic membrane was collected aseptically and stored for later use.

[0035] Place the allantoic membrane that has passed the virus in a tissue grinder, gradually add allantoic fluid, grind it thoroughly, and repeatedly freeze and thaw at -20°C for 4 times to fully release the virus particles from the group of cells. Add 1000IU / ml penicillin , Streptomycin, centrifuge at 3000r / min for 15min, take the supernatant and dilute it for 10 5 Tim...

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PUM

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Abstract

The invention discloses Chinese veterinary drug preparation for preventing or curing poultry respiratory diseases. The preparation is prepared by the following Chinese herbal medicines in part by weight: 20 to 28 parts of honeysuckle, 20 to 28 parts of houttuynia cordata, 18 to 23 parts of perillaseed, 18 to 23 parts of ephedra, 18 to 23 parts of cassia twig, 12 to 18 parts of gypsum, 12 to 18 parts of mulberry bark, 8 to 12 parts of burdock and 8 to 12 parts of scutellaria baicalensis. The Chinese veterinary drug preparation has a certain prevention effect on the poultry infectious laryngotracheitis, and can effectively protect poultry respiratory mucosa to prevent the occurrence of the poultry respiratory diseases; and the protection rate can reach 52%.

Description

Technical field [0001] The present invention belongs to the technical field of veterinary medicine. Specifically, it relates to a Chinese veterinary medicine preparation for preventing or treating respiratory diseases of poultry, in particular to a veterinary medicine preparation for preventing or treating chicken infectious laryngotracheitis. Background technique [0002] Poultry Infectious Laryngotracheitis (ILT) is an acute contact respiratory infectious disease caused by Poultry Infectious Laryngotracheitis virus (ILTV), which is characterized by difficulty breathing, coughing and coughing There is blood exudate, necropsy reveals swelling, bleeding and erosion of the larynx and tracheal mucosa. In the early stage of the disease, cells in the affected part can form nuclear inclusion bodies. The incidence of the disease is close to 100%, the mortality rate is 5%-70%, and the egg production rate of poultry has dropped significantly. The disease spreads quickly, can cause death ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/78A61P11/00A61P31/22
Inventor 张启迪单虎张传美蔡秀磊秦志华
Owner QINGDAO AGRI UNIV
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