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Antitussive preparation

An antitussive and drug technology, applied in the field of medicine, to achieve the effect of increasing the variety of clinical drugs, significant throat swelling and pain, and meeting clinical needs

Inactive Publication Date: 2013-06-12
史克勇
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, using the interaction of bitter almonds, Platycodon grandiflorum, pinellia and puffballs to formulate compatible prescriptions for the preparation of medicines for treating various coughs and itchy throats has not been reported yet.

Method used

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  • Antitussive preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1. Preparation of tablet

[0036] 600g of bitter almonds, 450g of bellflowers, 400g of pinellia, and 250g of puffballs.

[0037] 1) take the bitter almonds, platycodon grandiflorum, pinellia pinellia and puffballs of said parts by weight, and set aside;

[0038] 2) Add water to decoct the weighed bitter almonds, bellflowers, pinellia and puffballs together twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1 hour, combine Extract, filter, concentrate the filtrate to a relative density of 1.15-1.20, add ethanol until the alcohol content is 65%, stir evenly, refrigerate and stand still, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell and concentrate to a thick paste ;

[0039] 3) Dry and pulverize the above-mentioned thick paste to obtain the active ingredient of the medicine of the present invention, add binder, disi...

Embodiment 2

[0040] Embodiment 2. The preparation of capsule

[0041] Bitter almond 450g, platycodon 600g, pinellia 250g, puffball 400g.

[0042] 1) take the bitter almonds, platycodon grandiflorum, pinellia pinellia and puffballs of said parts by weight, and set aside;

[0043] 2) Add water to decoct the weighed bitter almonds, bellflowers, pinellia and puffballs together twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1 hour, combine Extract, filter, concentrate the filtrate to a relative density of 1.15-1.20, add ethanol until the alcohol content is 65%, stir evenly, refrigerate and stand still, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell and concentrate to a thick paste ;

[0044] 3) The above-mentioned thick paste is dried and pulverized to obtain the active ingredient of the medicine of the present invention, which is added into gran...

Embodiment 3

[0045] Embodiment 3. Preparation of granules

[0046] 750g bitter almond, 300g platycodon, 550g pinellia, 100g puffball.

[0047] 1) take the bitter almonds, platycodon grandiflorum, pinellia pinellia and puffballs of said parts by weight, and set aside;

[0048]2) Add water to decoct the weighed bitter almonds, bellflowers, pinellia and puffballs together twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1 hour, combine Extract, filter, concentrate the filtrate to a relative density of 1.15-1.20, add ethanol until the alcohol content is 65%, stir evenly, refrigerate and stand still, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell and concentrate to a thick paste ;

[0049] 3) Dry the above-mentioned thick paste, pulverize it, add powdered sugar and binder to make 1000 packs of granules.

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Abstract

The invention belongs to the technical field of medicine, and discloses an antitussive medicine and a preparation method thereof. The medicament is prepared from bitter apricot kernel, balloonflower root, pinellia tuber and puffball fruiting body. The medicament can be prepared into any clinical or pharmaceutically acceptable dosage forms, preferably oral preparation. The medicament has efficacies of clearing lung, eliminating phlegm, and relieving sore throat and a cough, and can be used for treating various cough and throat itch and pain.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an antitussive medicine and a preparation method thereof. Background technique [0002] Coughing is a protective respiratory reflex action of the human body. Cough occurs because when foreign bodies, irritating gases, respiratory secretions, etc. stimulate the receptors in the respiratory mucosa, the impulse is transmitted to the medullary cough center through afferent nerve fibers, causing coughing. The action of coughing is short and deep inhalation, the glottis is closed tightly, and the respiratory muscles, intercostal muscles, and diaphragm contract rapidly and violently, so that the high-pressure gas in the lungs is ejected, which becomes a cough. With the rushing out of the air, foreign bodies or secretions in the respiratory tract are expelled from the body. Traditional Chinese medicine believes that cough is a syndrome of sound and phlegm caused by exogeno...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61P11/14
Inventor 史克勇
Owner 史克勇
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