Pharmaceutical composition for treating diabetes, and preparation method thereof

A composition and diabetes technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of enhanced human tolerance, large dependence, and increased side effects of chemical drugs, and achieve good curative effect Effect

Inactive Publication Date: 2013-06-12
周昌明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are more than 20 commonly used hypoglycemic drugs in the treatment of diabetes, such as acarbose, metformin, gliclazide, glipizide, glipizide, glibenclamide, glimepiride, and single-component insulin. However, the side effects of chemical medicines increase, and long-term use will enhance human tolerance and greater dependence. Therefore, it is necessary to develop traditional Chinese medicine preparations with less toxic and side effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] This example is a granule, and the dosage of each raw material is astragalus 8kg, ginseng 3kg, trichosanthin 2kg, scrophulariae 2kg, Radix Ophiopogon japonicus 2kg, rehmannia glutinosa 2kg, kudzu root 3kg, hawthorn 3kg, poria cocos 2kg, licorice 2kg.

[0028] Prepared as follows:

[0029] Ginseng and trichosanthes are crushed into fine powder; take 8 traditional Chinese medicinal materials such as Astragalus, Scrophulariae, Ophiopogon japonicus, Rehmannia glutinosa, Pueraria root, hawthorn, Poria cocos, and licorice, soak in water for 1 hour, add 6 times the amount of water to decoct twice, the first time 3 hours for the first time, 1 hour for the second time, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.10-1.15 (60°C), let it cool, add an equal amount of ethanol, stir well, and let it stand for 24 hours. Filtrate, recover ethanol from the filtrate until the liquid is odorless, combine the above extracts, concentr...

Embodiment 2

[0032] This embodiment is a tablet, and the dosage of each raw material is: astragalus 12kg, ginseng 6kg, trichosanthin 6kg, scrophulariae 6kg, radix radix 4kg, rehmannia glutinosa 4kg, kudzu root 8kg, hawthorn 8kg, poria cocos 6kg, licorice 4kg.

[0033] Its preparation method is:

[0034] Ginseng and trichosanthes are crushed into fine powder; take 8 traditional Chinese medicinal materials such as Astragalus, Scrophulariae, Ophiopogon japonicus, Rehmannia glutinosa, Pueraria root, hawthorn, Poria cocos, and licorice, soak in water for 1 hour, add 6 times the amount of water to decoct twice, the first time 3 hours for the first time, 1 hour for the second time, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.10-1.15 (60°C), let it cool, add an equal amount of ethanol, stir well, and let it stand for 24 hours. Filtrate, recover ethanol from the filtrate until the liquid is odorless, combine the above extracts, concentrate t...

Embodiment 3

[0037] This example is a capsule, the dosage of each raw material is: astragalus 10kg, ginseng 4kg, trichosanthemi 3kg, crocodile 4kg, radix radix 3kg, rehmannia glutinosa 3kg, kudzu root 5kg, hawthorn 5kg, poria cocos 4kg, licorice 3kg.

[0038] Its preparation method is:

[0039] Ginseng and trichosanthes are crushed into fine powder; take 8 traditional Chinese medicinal materials such as Astragalus, Scrophulariae, Ophiopogon japonicus, Rehmannia glutinosa, Pueraria root, hawthorn, Poria cocos, and licorice, soak in water for 1 hour, add 6 times the amount of water to decoct twice, the first time 3 hours for the first time, 1 hour for the second time, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.10-1.15 (60°C), let it cool, add an equal amount of ethanol, stir well, and let it stand for 24 hours. Filtrate, recover ethanol from the filtrate until the liquid is odorless, combine the above extracts, concentrate to a clear...

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Abstract

The invention relates to a pharmaceutical composition for treating diabetes, and a preparation method thereof. Based on traditional Chinese medicine theories, the pharmaceutical composition comprises traditional Chinese medicine raw material medicines such as astragalus root, ginseng, trichosanthes root, scrophularia, ophiopogon tuber, rehmannia (fresh) kudzu root, hawthorn, poria, and licorice, is the efficacies of tonifying qi and yin, and engendering fluid and quenching thirst; can be used for wasting-thirst induced by deficiency of both qi and yin, type 2 diabetes; and has been used in clinical applications for many years, and the effect is significant.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a medicinal composition for treating diabetes and a preparation method of the composition; it belongs to the technical field of medicine. Background technique [0002] With the improvement of living standards, diabetes has become a common and frequently-occurring disease in my country, and its incidence is on the rise. Patients with type 2 diabetes account for more than 90% of the total number of DM patients. Most of them preserve their insulin secretion ability, but they are accompanied by insulin resistance, which manifests as a relative shortage of endogenous insulin. With the prolongation of the disease course, it can lead to chronic progressive lesions of multiple tissues and organs . [0003] Diabetes is a chronic disease that can cause multiple complications, including heart disease, stroke, renal failure and nerve damage, and has become a multiple disease tha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P3/10
Inventor 周昌明
Owner 周昌明
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