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Preparation method of medicine used after esophageal achalasia operation

A technology for achalasia and medicine is applied in the field of preparation of medicines for achalasia after operation, can solve the problem that esophageal reflux cannot be improved, and achieves the effects of reducing the type and dosage of medicines, facilitating the course of treatment and increasing the tension

Inactive Publication Date: 2013-06-12
鞠卫东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After endoscopic treatment, the recurrence rate is relatively high, and after surgery, achalasia of the cardia is controlled, but esophageal reflux cannot be improved
Therefore, there is currently a lack of a drug for improving esophageal relaxation imbalance after endoscopic treatment of achalasia and surgical treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1, the weight ratio of raw materials: 10 parts of litchi core, 6 parts of upland grass, 3 parts of poria cocos, 6 parts of tangerine peel, 3 parts of stalk grass, 6 parts of genus vine, 6 parts of kudzu root, 6 parts of aescin, 6 parts of loofah, 1 part of cat's claw, 3 parts of burnt malt, 10 parts of burnt grain sprouts.

Embodiment 2

[0035] Example 2, the weight ratio of raw materials: 20 parts of litchi core, 10 parts of upland grass, 6 parts of Poria cocos, 10 parts of dried tangerine peel, 6 parts of stalks, 10 parts of terrazzo, 10 parts of kudzu root, 10 parts of Aescin, 10 parts of loofah, 2 parts of cat's claw, 6 parts of burnt malt, 20 parts of burnt grain sprouts.

Embodiment 3

[0036] Example 3, the weight ratio of raw materials: 30 parts of litchi core, 12 parts of upland grass, 10 parts of poria cocos, 12 parts of tangerine peel, 10 parts of stalk grass, 12 parts of terrazzo, 12 parts of kudzu root, 12 parts of Aescin, 12 parts of loofah, 5 parts of cat's claw, 10 parts of burnt malt, 25 parts of burnt grain sprouts.

[0037] The Chinese medicine of embodiment 1~3 can be prepared by the following method:

[0038] (1) Extract the volatile oil from pueraria puerariae, upland grass, and stalk grass powder by steam distillation, and collect and mix for later use;

[0039] (2) Grind burnt grain buds and burnt malt through a 150-mesh sieve to form fine powder for later use;

[0040] (3) Mix lychee core, poria cocos, tangerine peel, twig, loofah, aescin, cat's claw, add 10 times the amount of water, add water to decoct twice, each time for 1 hour, combine the decoction, and let it stand; Then add 3 to 4 times of 95% ethanol to the decoction, let it stan...

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PUM

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Abstract

The invention discloses a preparation method of a medicine used after the esophageal achalasia operation, aiming to solve the problem of treatment of esophageal achalasia. The medicine is characterized by being prepared from the following active pharmaceutical ingredients by weight: lychee seeds, lindernia ruellioides, glabrous greenbrier rhizome, dried tangerine peel, sensitive joint vetch wood, Chinese starjasmine stem, kudzuvine root, Paris polyphylla Sm., luffa vegetable sponge, catclaw buttercup root, scorched malt and scorched rice sprout. The preparation method comprises the following steps of: (1) extracting essential oil from coarse powder of kudzuvine root, lindernia ruellioides and sensitive joint vetch wood for standby use; (2) grinding the scorched rice sprout into fine powder for standby use; (3) carrying out water extraction and alcohol precipitation on lychee seeds, glabrous greenbrier rhizome, dried tangerine peel, Chinese starjasmine stem, luffa vegetable sponge, Paris polyphylla Sm., catclaw buttercup root and scorched malt and obtaining primary materials after drying the products; and (4) spraying the essential oil into the primary materials, adding the scorched rice sprout fine powder, mixing the materials uniformly, sieving the mixture with a 60-mesh sieve and filling the mixture into a capsule, thus obtaining the medicine. Clinical experiments prove that the medicine has the characteristics of good curative effect and higher safety when being used after the esophageal achalasia operation and deserves clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method for postoperative medication for achalasia. Background technique [0002] Achalasia (esophageal achalasia) is an esophageal motility disorder, which refers to a disease in which there is no peristalsis in the esophageal body after swallowing and poor relaxation of the cardiac sphincter. It is characterized by impaired relaxation of the lower esophageal sphincter (LES) during swallowing, and lack of peristaltic contraction of the smooth muscle segment of the esophagus, resulting in functional esophageal obstruction. The cause of this disease is unknown. It may be related to toxins, nutritional deficiencies, genes and local inflammation. Clinical studies have found that mental concerns can aggravate children's symptoms. Consider whether cortical nerve dysfunction is caused by mental stimulation, leading to central and autonomic nervous dysfunction...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61K9/48A61P1/00
Inventor 张朋飞
Owner 鞠卫东
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