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Medicament for treating functional dyspepsia and preparation method thereof

A functional technology for dyspepsia, applied in the digestive system, drug combination, medical formula, etc., can solve the problems of unsatisfactory curative effect and easy recurrence of symptoms, and achieve the effect of less recurrence and good curative effect

Inactive Publication Date: 2013-09-11
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above commonly used prescriptions still have unsatisfactory curative effects, especially the problem that symptoms are easy to recur after drug withdrawal

Method used

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  • Medicament for treating functional dyspepsia and preparation method thereof
  • Medicament for treating functional dyspepsia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Embodiment 1 (granule):

[0051] Take 2500 grams of perilla, 2500 grams of citrus aurantium, 1700 grams of literature, 1700 grams of berberine, and 1600 grams of dried ginger, and implement according to the following steps:

[0052] (1) Weigh the raw material medicine according to the proportion, add water and decoct 3 times, add 8 times of water for the first time and boil, then boil for 30 minutes, add 7 times of water for the second time, boil for 40 minutes, and add water for 6 times for the third time After double boiling, boil for 60 minutes;

[0053] (2) Combine the decoctions, filter and concentrate the filtrate at 65°C to a clear paste with a density of 1.30, put it in an oven at 70°C to make a dry paste, and grind it into fine powder;

[0054] (3) Add an appropriate amount of dextrin and starch to the obtained dry cream powder to 900g, then add water to make granules, dry, granulate, pack into bags, and divide into 9g / bag (including 3.5g / bag of dry medicine pow...

Embodiment 2

[0055] Embodiment 2 (granule):

[0056] Take 2800 grams of perilla, 1500 grams of citrus aurantium, 1200 grams of literature, 1200 grams of berberine, and 1200 grams of dried ginger, and implement according to the following steps

[0057] (1) Weigh the raw materials according to the proportion, add water and decoct 3 times, boil for 40 minutes after the first 9 times of boiling, 50 minutes after the second 8 times of boiling, and 7 times of boiling for the third time Boil for 60 minutes;

[0058] (2) Combine the decoction, filter and concentrate the filtrate at 75°C to a clear paste with a density of 1.25, put it in an oven at 75°C

[0059] (3) Add an appropriate amount of dextrin and starch to the obtained dry cream powder to 900g, then add water to make granules, dry, granulate, pack into bags, and divide into 9g / bag (including 3.5g / bag of dry medicine powder) .

Embodiment 3

[0060] Embodiment 3 (granule):

[0061] Take 1500 grams of perilla, 2000 grams of citrus aurantium, 1500 grams of literature, 1500 grams of berberine, and 1500 grams of dried ginger, and implement according to the following steps:

[0062] (1) Weigh the raw material medicine according to the proportion, add water and decoct 3 times, boil for 30 minutes after 10 times boiling for the first time, decoct for 50 minutes after boiling for 9 times for the second time, and decoct for 50 minutes after boiling for 8 times for the third time Boil for 60 minutes;

[0063] (2) Combine the decoctions, filter and concentrate the filtrate at 85°C to a clear paste with a density of 1.20, put it in an oven at 80°C to make a dry paste, and grind it into fine powder;

[0064] (3) Add an appropriate amount of dextrin and starch to the obtained dry cream powder to 900g, then add water to make granules, dry, granulate, pack into bags, and divide into 9g / bag (including 3.5g / bag of dry medicine powd...

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Abstract

The invention discloses a medicament for treating functional dyspepsia. The medicament comprises an active component and a pharmaceutically acceptable excipient, wherein the active component is prepared from the following crude drugs in percentage by weight: 20-35 percent of purple perilla, 20-25 percent of immature citron fruit, 15-20 percent of zedoray rhizome, 15-20 percent of coptis chinensis and 15-20 percent of dried ginger. The medicament can be granules, capsules, tablets or pills. Through clinical verification, the medicament has the advantages of good symptom improvement, low relapse rate and no obvious toxic or side effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition prepared from raw materials of Chinese medicinal materials. technical background [0002] Functional dyspepsia refers to a group of symptoms such as abdominal pain, bloating, belching, anorexia, acid reflux, nausea, etc., excluding gastroesophageal reflux, gastroduodenal hepatobiliary and pancreatic diseases, systemic diseases, and certain drugs that damage the digestive tract It is an epigastric syndrome of unknown etiology. This disease is clinical common disease, frequently-occurring disease, accounts for the highest proportion in stomach disease, and the course of disease is long, easy to repeat. The study of its etiology is now believed to be related to the enteric nervous system: ① abnormal gastric motility, ② gastric hypersensitivity to certain stimuli, ③ mental state imbalance, ④ certain inflammatory stimuli, ⑤ partl...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/14A61P1/04
Inventor 刘子志尚文璠
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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