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Traditional Chinese medicine preparation for treating hemophilia and preparation method thereof

A technology of traditional Chinese medicine preparations and medicinal materials, which is applied in the field of pharmacy and achieves the effects of low drug cost, easy availability of raw materials and fast onset of effect.

Inactive Publication Date: 2013-09-18
全清清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease is mainly a hereditary disease, and there is no radical treatment in Western medicine at present, and the basic treatment is alternative therapy, and other drugs have temporary hemostatic effect

Method used

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  • Traditional Chinese medicine preparation for treating hemophilia and preparation method thereof

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Effect test

preparation example Construction

[0060] When the dosage form of the Chinese medicine preparation is syrup, its preparation method may further comprise the steps:

[0061] In the first step, water chestnuts, madder, buffalo horns, chickweed, agrimony, viola chinensis, mountain bean root, mountain maple, crushed dense flowers and licorice are mixed according to the stated ratio, and 4% of the obtained mixture is used. ~8 times the alcohol concentration of 75%~85% ethanol is dissolved, heated and refluxed for 4~6 hours, extracted, filtered to obtain the first filtrate; the filter residue is used again with 3~5 times the alcohol concentration relative to the obtained mixture quality Dissolve 80% to 90% ethanol, heat and reflux for 2 to 4 hours, extract and filter to obtain the second filtrate; combine the first and second filtrates, recover ethanol under reduced pressure and concentrate to a concentration of 0.6 to 0.6. 0.8g crude drug / mL, eluted with a macroporous adsorption resin column with a volume of 5L, fir...

Embodiment 1

[0071] Embodiment 1 Syrup of the present invention

[0072] Take 140g water chestnut, 260g madder, 140g buffalo horn, 190g astragalus, 270g chickweed, 230g codonopsis, 260g agrimony, 220g viola, 80g mountain bean root, 210g guoshanfeng, 240g rehmannia, 190g vanilla, white 190g Chine Root, 140g Cat's Claw, 230g Ziheche, 260g Antelope Horn, 280g Artemisia annua, 200g Lotus Pod, 210g Baiji, 320g Broken Dense Flower and 360g Licorice;

[0073] Its preparation method comprises the following steps:

[0074] In the first step, mix water chestnuts, madder, buffalo horn, chickweed, agrimony, purple flower, mountain bean root, mountain maple, crushed dense flower and licorice in proportion, and use 6 times the mass of the obtained mixture Dissolve in ethanol with an alcohol concentration of 80%, extract after heating and reflux for 5 hours, and filter to obtain the first filtrate; dissolve the filter residue again with ethanol with an alcohol concentration of 90% that is 3 times the ma...

Embodiment 2

[0078] Embodiment 2 Oral liquid of the present invention

[0079] Take 120g water chestnut, 240g madder, 170g buffalo horn, 130g astragalus, 290g chickweed, 210g codonopsis, 220g agrimony, 270g viola, 90g mountain bean root, 230g guoshanfeng, 210g rehmannia, 160g vanilla, white 200g Chine Root, 120g Cat's Claw, 250g Ziheche, 210g Antelope Horn, 220g Artemisia annua, 160g Lotus Pod, 240g White Chi, 270g Broken Dense Flower and 310g Licorice;

[0080] Its preparation method comprises the following steps:

[0081] The first step is to mix water chestnuts, madder, buffalo horns, chickweed, agrimony, mountain bean root, sweetgum velvet, imperata antelope horns and crushed flowers in proportion, and use methanol with an alcohol concentration of 85% as Solvent, adopt the percolation method to percolate slowly at a speed of 2ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is pulverized into powder; the quality of ...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating hemophilia and a preparation method thereof. The traditional Chinese medicine is prepared from the following crude drugs of water chestnut, radix rubiae, buffalo horn, astragalus membranaceus, chickweed, codonopsis pilosula, hairyvein agrimony, herba violae, subprostrate sophora, celastrus aculeatus, dried rehamnnia root, fragrant hair grass, lalang grass rhizome, radix ranunculi ternate, placenta hominis, antelope horn, sweet wormwood, receptaculum nelumbinis, rhizoma bletillae, broken dense flowers and liquorice. The traditional Chinese medicine preparation has the beneficial effects that the traditional Chinese medicine preparation is a pure traditional Chinese medicine preparation, free of toxic and side effects, accurate in effect of bleeding pain, fast to become effective, good in treatment effect, convenient to take, available in materials, and low in drug cost, does not generate the drug dependence after being taken for a long period of time, and can help a sufferer get rid of whole blood and blood coagulation factors; the economical burden on treatment of the sufferer is reduced.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine preparation for treating hemophilia and a preparation method thereof. Background technique [0002] Hemophilia is a group of bleeding disorders caused by inherited deficiencies of clotting factors. Coagulation factors are a group of biologically active proteins in the human body that can cause blood coagulation and have the function of hemostasis. There are thirteen main coagulation factors, which are commonly expressed in Roman numerals: I, II...XIII (coagulation factors one, two ... to thirteen). If there is a lack of a certain coagulation factor in the blood, the blood is not easy to coagulate, thus causing bleeding disorders. In my country, the incidence rate of hemophilia in the social population is 5-10 / 100,000, and the incidence rate of infants is about 1 / 5000. Typical hemophilia patients often develop coagulation dysfunction since childh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P7/00A61P7/04A61K35/50A61K35/32
Inventor 全清清
Owner 全清清
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