Liquid chip kit for diagnosing lung cancer

A liquid phase chip and lung cancer diagnosis technology, applied in the field of medicine and biology, can solve the problems of missed diagnosis, weak specificity, and low sensitivity of patients, and achieve the effect of high accuracy.
CN103389375AInactive Publication Date: 2013-11-13HENGDIAN GRP JIAYUAN CHEM +2
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HENGDIAN GRP JIAYUAN CHEM
Publication Date
2013-11-13
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a liquid chip kit for diagnosing lung cancer. The kit comprises microballs coated with capturing antibodies, detecting antibodies labeled by biotin, microballs coupled with Halotag Amine (O2) ligand, antigen proteins, streptavidin-phycoerythrin and anti-human immune globulin G labeled by biotin; wherein the capturing antibodies contain at least one component, which is selected from the following capturing antibodies: CRP, Prolactin, CEA, NSE, CK19, Axl and ADAM8; the detecting antibodies contain at least one component, which is selected from the following detecting antibodies: CRP, Prolactin, CEA, NSE, CK19, Axl and ADAM8, and are corresponding to the capturing antibodies; the antigen proteins contain at least one component, which is selected from following components: p62, CTAG, p53 and CAGE. Microballs with different antibodies or antigen proteins have different color codes. The liquid chip kit carries out detections of antigen and autoantibody at the same time, and the precision rate is high.
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Description

technical field

[0001] The invention relates to the field of medicine and biology, in particular to a liquid phase chip kit for lung cancer diagnosis. Background technique

[0002] Lung cancer is currently the malignant tumor with the highest morbidity and mortality worldwide. In the past 20 years, due to the vigorous promotion of smoking cessation, the incidence of male lung cancer in Western countries such as Europe and the United States has begun to decline. But the incidence of lung cancer in women continues to rise. my country is a big country in the production and sales of cigarettes, regardless of men or women. The incidence of lung cancer has continued to rise, especially in women. Clinical studies have shown that the cure rate of carcinoma in situ is close to 100%. The 5-year survival rate of patients with stage I lung cancer is 60% to 90%, while the 5-year survival rate of patients with stage IIIb and IV lung cancer is only 5% to 20%. It suggested that early d...

Claims

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