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A kind of wettable ivermectin oxygen albendazole powder

A technology of ivermectin oxygen albendazole powder and oxygen albendazole, applied in the field of wettable ivermectin oxygen albendazole powder and its preparation, can solve the problem of ivermectin oxygen albendazole The use of azole powder is inconvenient, etc., to achieve the effect of increasing food-attracting function, low production cost, and simple preparation process

Inactive Publication Date: 2016-03-16
CHENGDU QIANKUN VETERINARY PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims at the disadvantage of inconvenient use of the existing ivermectin oxygen albendazole powder, and provides a method of uniformly mixing ivermectin during preparation, which can be uniformly dispersed in water, and administered by drinking water or spraying on feed Ivermectin Oxy Albendazole Powder

Method used

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  • A kind of wettable ivermectin oxygen albendazole powder
  • A kind of wettable ivermectin oxygen albendazole powder
  • A kind of wettable ivermectin oxygen albendazole powder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1 Preparation of wettable ivermectin oxygen albendazole powder of the present invention

[0026] Take oxygen albendazole 4g, ivermectin 0.4g, magnesium stearate 2g, sugar powder 61g, sodium lauryl sulfate 7g, xanthan gum 4g, fresh milk essence 0.8g, sodium saccharin 0.8g, lemon sodium nitrite 20g; after the above-mentioned raw materials are mixed uniformly, be pulverized to 200 mesh ultrafine powder, pack, obtain wettable ivermectin oxygen albendazole powder of the present invention.

Embodiment 2

[0027] Embodiment 2 Preparation of wettable ivermectin oxygen albendazole powder of the present invention

[0028] Take oxygen albendazole 5g, ivermectin 0.2g, magnesium stearate 2.5g, sugar powder 54.5g, sodium lauryl sulfate 9g, xanthan gum 2g, fresh milk essence 0.9g, sodium saccharin 0.9g 1. Sodium citrate 25g, after above-mentioned raw material is mixed, be pulverized to 200 purpose superfine powders, pack, obtain wettable ivermectin oxygen albendazole powder of the present invention.

Embodiment 3

[0029] Embodiment 3 The compatibility screening of raw and auxiliary materials of wettable ivermectin oxygen albendazole powder

[0030] (1) Preparation of different formula products

[0031] Get the raw and auxiliary materials in the formula in Table 1, and prepare wettable ivermectin oxygen albendazole powder according to the method of Example 1.

[0032] Table 1 The preferred scheme of wettable ivermectin oxygen albendazole powder formula

[0033]

[0034]

[0035] (2) Quality evaluation of wettable ivermectin oxygen albendazole powder

[0036] Dispersion evaluation: Take 1 g of each wettable ivermectin oxygen albendazole powder prepared according to formula 1 to formula 6 in Table 1, put it into 1000 ml of drinking water, observe or stir and observe its dispersion. If the dispersion is slow and uneven, it is rated as "poor"; if the dispersion is slow, there are agglomerates or particles during the dispersion process, and it can be dispersed evenly after proper stir...

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Abstract

The invention provides a wettable ivermectin albendazole oxide powder which is prepared from the following raw and auxiliary materials in parts by weight: 2.5-10 parts of albendazole oxide, 0.1-0.8 part of ivermectin, 0.5-3 parts of magnesium stearate, 43.9-74 parts of powdered sugar, 3-11 parts of sodium lauryl sulfate, 0-8 parts of xanthan gum, 0.6-1 part of fresh milk essence, 0.6-1 part of soluble saccharin and 10-30 parts of sodium citrate. The invention also provides a preparation method and application of the wettable ivermectin albendazole oxide powder. According to the invention, the dispersity of ivermectin and albendazole oxide in water is obviously enhanced, so that the ivermectin and albendazole oxide can be uniformly distributed in water for a long time, thereby facilitating administration by drinking water in clinic; the ivermectin albendazole oxide powder with the additional function of feed attraction has the function of feed attraction when being used for pigs and other animals with sensitive gustation; and the invention has the advantages of simple preparation technique and low production cost, and is suitable for industrialized mass production.

Description

technical field [0001] The invention relates to a wettable ivermectin oxygen albendazole powder and a preparation method and application thereof. Background technique [0002] Ivermectin Oxyalbendazole Powder is a compound anthelmintic drug composed of ivermectin and Oxyalbendazole. Among them, ivermectin is an avermectin drug (Avermectins), which has a strong killing effect on most nematodes and arthropods. Studies have found that ivermectin is effective against nematodes such as Trichocymidae, Cylindidae, Cystidae, Microbaculidae, Ascaridae, Acroceridae, Filaridae, Trichocephalidae, Suckingidae, and Dictyoceridae in livestock and poultry. It has a good repelling effect, some are effective for the adult stage, some are effective for the larval stage, and some are effective for the entire developmental stage; some nematodes that can't be killed by most anthelmintics can live in the fourth stage of the organization for a long time For larvae, ivermectin also has a high kill...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K9/14A61P33/00A61P33/10A61K31/4184
Inventor 丁晓刚房春林李犹平杨海涵
Owner CHENGDU QIANKUN VETERINARY PHARMA
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