Preparing method of herba violae extract and application of herba violae extract in hypoglycemic agents

Abstract

The invention relates to a preparing method of herba violae extract and application of the herba violae extract in hypoglycemic agents. The preparing method of the herba violae extract can be used for effectively extracting substances used for preparing the hypoglycemic agents from herba violae. According to the preparing method of the herba violae extract, herba violae is smashed into powder and is then immersed in ethyl alcohol for 0.5h, reflux extraction is then carried out twice, extraction liquid is obtained after filter residues are eliminated, extraction liquid is depressurized and concentrated till no alcohol taste exists, the concentration of the liquid is then adjusted till the crude drug content reaches 0.5g / ml, and then sample liquid is obtained; AB-8 type macroreticular resin columns are formed in the sample liquid; elution is carried out with water to obtain elution liquid I, and then the elution liquid is discarded; elution is carried out with ethyl alcohol to obtain elution liquid, the ethyl alcohol is then depressurized and recycled, and then herba violae total flavone is obtained after concentration and drying. The herba violae total flavone can be used for preparing the hypoglycemic agents effectively to achieve the application of the herba violae total flavone in the preparation of the hypoglycemic agents. According to the preparing method of the herba violae extract and the application of the herba violae extract in the hypoglycemic agents, raw materials are abundant, the preparing method is simple, and the prepared herba violae total flavone has a hypoglycemic effect and can be used for preparing the hypoglycemic agents effectively.

Description

technical field [0001] The invention relates to medicine, in particular to a preparation method of Viola didin extract and its application in hypoglycemic drugs. Background technique [0002] Diabetes is a chronic metabolic disease characterized by chronic hyperglycemia caused by the interaction of environmental factors and genetic factors. Its symptoms are usually referred to as "hyperglycemia" in China. Long-term high blood sugar can lead to microvascular endothelial lesions, and the accompanying abnormal protein and fat metabolism can cause abnormalities in the structure and function of the heart, brain, kidney, nerves, blood vessels, etc., and even lead to organ failure and life-threatening. The alias given to it by fun is the "silent killer", especially adult-onset diabetes. Diabetic patients can reduce their life expectancy by an average of ten years. And the complications that occur can spread all over the body. The complications of diabetes include: autonomic nervou...

AI Technical Summary

Problems solved by technology

It has antibacterial, anti-inflammatory, anti-endotoxin, and immune-enhancing effects, but there is no public report on the effect of Viola didin single herb or Viola dicin extract on diabetes and how to prepare the extract.

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