A transdermal drug delivery therapeutic instrument and a transdermal drug delivery treatment method

Abstract

The invention discloses a transdermal drug delivery treatment device, which includes a power circuit, an MCU main control module, a human-computer interaction device, an electroporation / ion introduction circuit, an ultrasonic introduction circuit and two treatment electrodes. The ultrasonic introduction circuit includes ultrasound Oscillation circuit and modulation circuit, the signal output end of the modulation circuit is connected with the modulation signal input end of the ultrasonic oscillation circuit, and the modulation circuit is used to modulate the ultrasonic signal generated by the ultrasonic oscillation circuit to obtain multiple ultrasonic signals of different frequencies. The invention also discloses a percutaneous drug delivery treatment method. The ultrasonic introduction treatment method is as follows: one ultrasonic transducer corresponds to an ultrasonic oscillation circuit, and the ultrasonic signal of the ultrasonic oscillation circuit is modulated to obtain ultrasonic signals of multiple frequencies. transmitted to the ultrasonic transducer. Through the present invention, it is possible to perform electroporation / iontophoresis drug delivery treatment and ultrasonic wave introduction drug delivery treatment on patients at the same time, so that drugs can be quickly and effectively introduced into the skin to achieve better therapeutic effects.

Description

technical field [0001] The present invention relates to a transdermal drug delivery therapeutic instrument and a transdermal drug delivery treatment method, in particular to a transdermal drug delivery therapeutic instrument and a transdermal drug delivery treatment with the functions of electroporation / iontophoresis drug delivery and ultrasonic therapy. drug treatment methods. Background technique [0002] The transdermal drug delivery system refers to a treatment method in which the drug penetrates the skin and enters the circulatory system after being administered through the skin. Transdermal drug delivery has the unique advantage of surpassing general drug delivery methods. It can avoid the "first-pass effect" of the liver and the destruction of the gastrointestinal tract, and the interlayer of the skin also has a storage function. It makes the drug concentration curve gentle, avoids the "peak-valley phenomenon", provides a predictable and long action time, maintains a...

AI Technical Summary

Problems solved by technology

However, this study uses two ultrasonic transducers to work at the same time. Although it has achieved relatively good results, the structure of the two transducers used at the same time is complex, bulky, and does not have engineering practicability and cannot be used for clinical treatment.

[0019] During drug introduction, due to the complex composition of drugs, similar and diverse molecules, different molecular weights, and large structural differences, it is necessary to find out the corresponding and different combinations of treatment parameters for different drugs through experiments, including electroporation and electroporation. The combination of parameters such as waveform, frequency, duty cycle, ultrasound, etc., all of which need to be tested and determined for different drugs, so the instrument must have a built-in combination of treatment parameters corresponding to various drugs. If all drugs use only one fixed import parameters, some drugs will have very poor import effect

Images