Haemostatic dressing and production method thereof

A technology of hemostatic dressing and chitosan, which is applied in the fields of medical science, bandages, absorbent pads, etc., can solve the problems of reduced hemostatic ability of dressings, lowering the proportion of chitosan fibers, etc., and achieves both hemostatic effect and stress strength, Accelerated hemostasis speed, high stress strength effect

Active Publication Date: 2015-03-11
BENQ MATERIALS +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, adding another water-insoluble material can maintain the dressing stress, but at the same time, it will also reduce the proportion of chitosan fibers, resulting in a decrease in the hemostatic ability of the dressing

Method used

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  • Haemostatic dressing and production method thereof
  • Haemostatic dressing and production method thereof
  • Haemostatic dressing and production method thereof

Examples

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preparation example Construction

[0037] Following is the preparation of hemostatic dressing of the present invention:

[0038] 1,000 grams of acetic acid and 19,000 grams of alcohol were mixed to form an acidic organic solution (pH about 4.7), and then 300 grams of chitosan fibers (purchased from Hayes Moore, China) were dissolved in the acidic organic solution and stirred for 2 hours , forming an acidified chitosan fiber solution. Next, put the fibers into a dehydrator, centrifuge for 2 minutes, and perform dehydration. Then put the fibers into an oven, set the temperature at 75° C. and bake for 180 minutes to form acidified chitosan fibers.

[0039]300 grams of chitosan fibers (purchased from Haysmore, China) and 50 grams of crosslinking agent glutaraldehyde were dissolved in 10000 grams of 0.5% alcohol solution. After stirring and reacting for 2 hours, a cross-linked chitosan fiber solution is formed. Next, put the fibers into a dehydrator, centrifuge for 2 minutes, and perform dehydration. Then put th...

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Abstract

The invention provides a haemostatic dressing and a production method thereof. The haemostatic dressing comprises 25 to 50 wt% of a chitosan fiber having undergone acid treatment and 50 to 75 wt% of a chitosan fiber having undergone cross-linking treatment. The haemostatic dressing provided by the invention has an excellent haemostatic effect and can maintain high stress intensity in use.

Description

technical field [0001] The present invention relates to a hemostatic dressing and its manufacturing method, and in particular to a hemostatic dressing containing chitosan fiber and its manufacturing method. Background technique [0002] Chitosan is a polymer obtained by deacetylation of chitin, which is a natural polymer extracted from organisms, mainly found in crustaceans (shrimp, crab, etc.) ), in insect shells, or in the cell walls of fungi. Chitin is a linear polysaccharide polymer formed by β-1,4 bonds of glucosamine and N-acetylglucosamine. Chitosan can be used in biomaterials and medical materials because of its good biocompatibility, bioactivity, non-cytotoxicity and biodegradability with cells. Chitosan has a positive charge in an acidic solution, so it can attract platelets to aggregate, thereby achieving rapid hemostasis. [0003] At present, dressings composed of chitosan non-woven fabrics have been widely used in clinical practice. However, chitosan dressing...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/44
Inventor 张国勇
Owner BENQ MATERIALS
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