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Application of umbelliferone in preparing anti-eimeria tenella medicine

A technology of umbelliferin and Eimeria, which is applied in the direction of anti-infective drugs, drug combinations, active ingredients of heterocyclic compounds, etc., and can solve problems such as the inability to infer the effect of anti-Eimeria tenella

Active Publication Date: 2014-02-12
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] As a drug with antibacterial, anticancer and antihypertensive application prospects, umbelliferone has attracted much attention in recent years, but there is no report that umbelliferide has anti-Eimeria tenella. The known properties of analactone cannot be inferred whether it has anti-Eimeria tenella

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Preparation of Umbelliferone Powder: Take 3g Umbelliferone (content not less than 99%) and 97g starch and mix well.

[0011] The usage and dosage of the powder: mix the above 100g powder into 100kg feed, and feed according to the daily food intake.

Embodiment 2

[0013] Preparation of Umbelliferone Water-Soluble Powder: Take 3g of Umbelliferone (content not less than 99%) and 97g of glucose and mix well.

[0014] Usage and dosage of water-soluble powder: Dissolve the above-mentioned 100g powder in 200L water, cut off the water for 2 hours before the medicine, and then feed according to the normal drinking water amount.

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PUM

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Abstract

The invention discloses an application of umbelliferone in preparing an anti-eimeria tenella medicine. The umbelliferone and an acceptable auxiliary material are prepared as powder which is added into feed and uniformly mixed and is used for feeding chicken according daily feed amount. Or, the umbelliferone is prepared as umbelliferone water soluble powder which is dissolved in water and is used for feeding chicken according to daily water consumption. Animal infection experiments verify that the anticoccidial index (ACI) of the umbelliferone can reach over 165, and the umbelliferone has a better anti-eimeria tenella effect.

Description

technical field [0001] The invention relates to a new application of umbelliferin, in particular to the application of umbelliferin in preparing anti-Eimeria tenella medicaments. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers the intensive chicken industry production, and the economic loss caused by it is as high as more than 2.5 billion pounds every year. Eimeriaspp ), the most harmful of which is Eimeria tenella ( Eimeria tenella ). Although my country has no accurate statistics on this so far, the most conservative estimate is that the loss should not be less than 2.5 billion RMB. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Umbelliferone (Umbelliferone), also known as umbelliferone; 7-hydroxycoumarin, ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/37A61P33/02
Inventor 廖申权孙铭飞谢明权戚南山吴彩艳吕敏娜温列娜
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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