Blood oxygen blood volume absolute amount detection device and method thereof

Abstract

The invention discloses a blood oxygen blood volume absolute amount detection device which comprises a power source, a sensing and detecting probe, an amplifying filtering circuit, a time sequence control circuit and a data collecting module. The sensing and detecting probe detects the blood oxygen blood volume absolute amount of brain tissues of the human body through illumination under the supporting of the power source and comprises the power source and a photosensitive detector, the amplifying filtering circuit is in electric communication with the sensing and detecting probe and outputs amplified and filtered signals to the data collecting module under the supporting of the power source, meanwhile the sensing and detecting probe, the amplifying filtering circuit and the data collecting module are respectively in electric communication with the time sequence control circuit and are controlled by the time sequence control circuit, the data collecting module is connected with a PC, and the PC controls the detection device and displays and stores the detected data. The blood oxygen blood volume absolute amount detection device is obtained by means of the structure or the combination of the structure, and therefore the detection device has the advantages of being used in real time, being portable and low in cost, and measuring the blood oxygen blood volume absolute amount rapidly and accurately.

Description

technical field [0001] The invention relates to a medical instrument, in particular to a device for detecting the absolute amount of blood oxygen and blood volume and a method thereof. Background technique [0002] Measuring the concentration of blood oxygen in local tissues of the human body and observing its change over time will help to understand the absolute value concentration of blood oxygen in patients with brain diseases and patients during surgery, and provide a basis for doctors' diagnosis. [0003] Compared with widely used medical detection techniques: magnetic resonance imaging (fMRI), positron emission tomography (PET), electroencephalography / time-related potential (EEG / ERP), emerging near-infrared brain function spectroscopy or imaging (NIRS / fNIRI) has the advantages of portability, low cost, high temporal resolution, and non-invasive detection. As a non-invasive optical monitoring method, near-infrared spectroscopy is increasingly used to observe hemodynam...

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Problems solved by technology

For example, the Chinese patent ZL 200310113534.7 proposes a detection method for the oxygen saturation of local brain tissues of newborns under the stimulation of oxygen inhalation. However, it is difficult to meet the absolute measurement, so it is difficult to reflect the difference between the patient and the normal person, or the difference between the diseased area and the normal area; Shuangru ZL 200610112598.9 Chinese patent, which provides a detection method for the absolute amount of oxygenated and reduced hemoglobin in human tissues , and only measure the relative amount of oxygenated and reduced hemoglobin in human tissue, and cannot provide an accurate measurement of the baseline, so it is impossible to realize the detection of the absolute amount; for example, in the published related technical literature, most of them use the frequency domain The method of measuring the blood oxygen parameters of human tissue

For example, the M.A. McIntosh team has measured the absolute amount of oxygenated hemoglobin in brain tissue through the method of multi-distance frequency domain measurement (FDMD), but this method uses optical fiber bundles and the cost is too high

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