Nanocapsule for promoting blood circulation and preparation method thereof
A technology of capsules and Tongmai, which is applied in the field of Chinese patent medicine capsules and its preparation, can solve problems such as unqualified subpackage volume, difficult subpackage operation, and long disintegration time, so as to reduce water content and improve stability , Improve the effect of disintegration time
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[0028] Example 1
[0029] Salvia 500g Chuanxiong 500g
[0030] Pueraria lobata 500g dextrin 15g
[0031] Microcrystalline cellulose 10g
[0032] 1) Crushing: respectively crush Danshen, Chuanxiong and Pueraria lobata root through a 200-mesh sieve (the mesh number of the sieve is subject to Taylor's), and sterilize to obtain the raw material of nano powder;
[0033] 2) Adhesive: Prepare 2% dextrin aqueous solution and put it in a spray tank for later use;
[0034] 3) Mixing granulation: Pass the microcrystalline cellulose through a 100-mesh sieve, weigh 15g and the prescribed amount of nano-powder raw materials into the feeding cart of the one-step granulator, turn on the fan and heat, so that the material will evenly heat up in a fluidized state. Turn on the spray button, spray in 2% dextrin aqueous solution, adjust the liquid inlet speed to 27ml / min, atomization pressure 0.10~0.12MPa, inlet temperature 80~85℃, material temperature 43~45℃, until the 2% dextrin aqueous solution is all S...
Example Embodiment
[0036] Example 2
[0037] Salvia 800g Chuanxiong 800g
[0038] Pueraria 800g dextrin 15g
[0039] Microcrystalline cellulose 15g
[0040] (1) Crushing: pulverize Salvia miltiorrhiza, Chuanxiong and Pueraria lobata root respectively through a 200-mesh sieve and sterilize to obtain nano-powder raw materials;
[0041] (2) Adhesive: prepare 2% dextrin aqueous solution and put it in a spray tank for later use;
[0042] (3) Mixing granulation: microcrystalline cellulose is passed through a 100-mesh sieve, and 15g and the prescription amount of nano-powder raw materials are weighed into the feeding cart of the one-step granulator, the fan is turned on and heated, so that the material is evenly heated in a fluidized state , Turn on the spray button, spray in 2% dextrin aqueous solution, adjust the liquid inlet speed to 26ml / min, atomization pressure 0.10~0.12MPa, inlet temperature 80~85℃, material temperature 45~47℃, until all the adhesive is sprayed , Drying, cooling and discharging to obtain...
Example Embodiment
[0044] Example 3
[0045] Salvia 1000 Chuanxiong 1000
[0046] Pueraria 1000 dextrin 10g
[0047] Microcrystalline cellulose 20g
[0048] (1) Crushing: pulverize Salvia miltiorrhiza, Chuanxiong and Pueraria lobata root respectively through a 200-mesh sieve and sterilize to obtain nano-powder raw materials;
[0049] (2) Adhesive: prepare 2% dextrin aqueous solution and put it in a spray tank for later use;
[0050] (3) Mixed granulation: microcrystalline cellulose is passed through a 100-mesh sieve, 20g and the prescribed amount of nano-powder raw materials are weighed into the feeding cart of the one-step granulator, the fan is turned on and heated, so that the material is evenly heated in a fluidized state , Turn on the spray button, spray in the dextrin aqueous solution, adjust the liquid inlet speed to 25~32ml / min, atomization pressure 0.10~0.12MPa, inlet temperature 80~85℃, material temperature 43~47℃, until the dextrin aqueous solution is completely sprayed Enter, dry, and dischar...
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