Dispersible tablet of maca, preparation method and application thereof
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A technology for dispersible tablets and maca, applied in the field of health care, can solve the problems of poor drug compliance, limited application of maca, disintegration speed, solubility and bioavailability of chewable tablets or capsules, etc. Dissolution time, rapid dissolution, and improved dispersion uniformity
Active Publication Date: 2014-03-26
CHONGQING XIXUAN BIOTECH CO LTD
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Problems solved by technology
At present, most of the application of maca is in the form of wine, which greatly limits the application of maca due to the limitations of the wine itself.
There are also a small number of people who make maca powder or maca crude extract into preparations such as chewable ta
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Embodiment 1
[0026] Example 1 Preparation of Maca Dispersible Tablets of the Invention
[0027] Mix 580g of maca powder, 80g of cross-linked polyvinylpyrrolidone, 0.45g of sodium lauryl sulfate, 40g of maltodextrin, 280g of microcrystalline cellulose, and 10g of aspartame. A soft material made of 80% ethanol is passed through a 14-mesh sieve for granulation, dried at 60°C for 2 hours, passed through a 20-mesh sieve for granulation, and then 10 g of magnesium stearate is added. Mix and press to prepare maca dispersible tablets of the present invention.
Embodiment 2
[0028] Example 2 Preparation of Maca Dispersible Tablets of the Invention
[0029] Mix 680g of maca powder, 150g of low-substituted hydroxypropyl cellulose, 0.45g of sodium lauryl sulfate, 10g of mannitol, 140g of microcrystalline cellulose, and 10g of stevia, and add 5% polyvinylpyrrolidone to 80% The soft material is made from the ethanol solution of 5%, passed through a 14-mesh sieve for granulation, dried at 60°C for 2h, passed through a 20-mesh sieve for granulation, and then added 10g of talc. Mix and press to prepare maca dispersible tablets of the present invention.
Embodiment 3
[0030] Example 3 Preparation of Maca Dispersible Tablets of the Invention
[0031] Mix 550g of maca powder, 200g of sodium carboxymethylcellulose, 11.25g of poloxamer, 89g of lactose, 500g of microcrystalline cellulose, and 25g of sucrose, mix well, and add 70% ethanol with a wet volume percentage to make soft Granulate through a 14 mesh screen, dry at 60°C for 2 hours, pass through a 20 mesh screen, and then add 10g magnesium stearate. Mix and press to prepare maca dispersible tablets of the present invention.
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Abstract
The invention provides a dispersible tablet of maca. The dispersible tablet is prepared by the following components of: 48%-78% of maca powder, 3%-20% of crospolyvinylpyrrolidone, 0.1%-35% of maltodextrin, 5%-30% of microcrystalline cellulose, 0.03%-1% of sodium lauryl sulfate, 0.1%-3% of aspartame, 0.5%-3% of magnesium stearate and a proper amount of bonding agent. The prepared dispersible tablet of the maca has the advantages that the tablet is high in disintegration and high in dispersing uniformity, has obvious functions for relieving the physical fatigue and improving the sexual function, is good in drug compliance, and is especially applicable to old people and patients with difficulty in swallowing. A preparation method of the dispersible tablet of the maca has the advantages that the process is simple, the operation is controllable, new equipment does not need to be added, and the suitability for industrial and large-scale production is achieved.
Description
Technical field [0001] The invention belongs to the field of health care, and particularly relates to a maca dispersible tablet and a preparation method and application thereof. Background technique [0002] Maca (Maca), native to the Andes of South America at an altitude of 3500-4500 meters, is now mainly distributed in the Puno Ecological Area in central Peru and the city of Puno in southeastern Peru. It is a Lepidium plant in the Cruciferae family. At present, the United States, Japan, Spain, Ecuador, Bolivia, Australia, etc. have been successfully planted. The nutrient composition of maca cultivated in Yunnan is similar to maca produced in Peru. [0003] Maca has the effects of improving fertility, improving sexual function, anti-cancer, anti-leukemia, and treating menopausal syndrome, and is mainly used as a health product. At present, most of the applications of maca are in the form of sparkling wine. Due to the limitations of sparkling wine itself, the application of maca ...
Claims
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Application Information
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