Test strip card based on quantum dot labeling

A quantum dot and test strip card technology, applied in the field of quantum dot-marked test strip cards, can solve the problems of low detection efficiency, low sensitivity, and no rapid immunochromatographic test strip products, etc. short time effect

Inactive Publication Date: 2014-03-26
CHENGDU LINGYU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages are: (1) It can only detect samples qualitatively, but it is difficult to achieve quantitative samples
(2) It is difficult to detect multiple components of the sample at the same time, and the detection efficiency is low
(3) For some samples with extremely low antigen or antibody content, the color of colloidal gold is very light, it is difficult to judge the result with the naked eye, and the detection sensitivity is low
Although the patent can realize simultaneous detection of multiple components, what is claimed is a method, and no claim is made for the rapid immunochromatographic test strip product based on quantum dot labeling
Moreover, this method has deficiencies: (1) To achieve multi-component detection of samples, multiple corresponding detection lines need to be set on the analysis membrane at the same time, that is, each detection line is only used to detect one indicator in the sample, and the detection efficiency is low
(2) Use ultraviolet light to irradiate the test...

Method used

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  • Test strip card based on quantum dot labeling
  • Test strip card based on quantum dot labeling
  • Test strip card based on quantum dot labeling

Examples

Experimental program
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Effect test

Embodiment 1

[0036] Figure 1-4 Embodiment 1 will be described. Embodiment 1 is one of the preferred schemes of the quantum dot labeled test strip card of the present invention.

[0037] Figure 1-4 Among them, the quantum dot labeling test strip card of the preferred solution includes a cartridge 3 and a quantum dot labeling test strip 2 . The quantum dot marking test strip 2 includes a sample suction pad 4 , a marking pad 5 , an analysis membrane 7 , and a water absorption pad 8 which are sequentially overlapped and fixed on the substrate 1 . The analytical membrane 7 has a detection zone 6 . One end of the cartridge 3 together with the opening on the upper surface of the cartridge end forms a test strip slot opening 12, so that the quantum dot marked test strip 2 can be inserted into the cartridge 3 at present. The test strip 2 is a detached and plug-in structure of the cartridge 3 . When the sample is tested, one end of the sample suction pad 4 of the test strip 2 inserted into th...

Embodiment 2

[0047] Figure 5-8 Embodiment 2 will be described. Embodiment 2 is another preferred solution of the quantum dot labeled test strip card of the present invention.

[0048] Figure 5-8Among them, the quantum dot labeling test strip card of the preferred solution includes a cartridge 3 and a quantum dot labeling test strip 2 . The quantum dot marking test strip 2 includes a sample suction pad 4 , a marking pad 5 , an analysis membrane 7 , a water absorption pad 8 and a test strip reaction end point indicating label 9 which are sequentially overlapped and fixed on the substrate 1 . The analytical membrane 7 has a detection zone 6 . One end of the cartridge 3 together with the opening on the upper surface of the cartridge end forms a test strip slot opening 12, so that the quantum dot marked test strip 2 can be inserted into the cartridge 3 at present. The test strip 2 is a detached and plug-in structure of the cartridge 3 . When the sample is tested, one end of the sample su...

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Abstract

The invention relates to the field of in-vitro diagnosis, particularly a test strip card based on quantum dot labeling. The test strip card comprises a card box (3) and a quantum dot labeling test strip (2), wherein one end of the card box (3) is open to form a test strip slot (12), and the test strip (2) is in a card box (3) instant-plug structure; and the card box (3) is provided with a storage medium (13) in which a sample tested object standard curve and other information are stored. When detecting a sample, one end of a sample suction pad (4) of the test strip (2) inserted into the card box (3) excessively protrudes out of the open end of the card box (3) so as to impregnate and absorb the sample, and an instrument with signal detection function acquires characteristic signals of a test strip (2) detection belt (6) and calculates the sample single component or multicomponent concentration in combination with tested object standard curve or coefficient parameters simultaneously read from the storage medium (13) by the instrument. The test strip card for detecting samples has is simple and quick, and has the characteristics of high sensitivity, objective result, high use flexibility and the like.

Description

technical field [0001] The invention belongs to the field of in vitro diagnosis, and specifically relates to a quantum dot marker which has detection information such as a standard curve or coefficient parameters of the tested object, and can quickly quantify the concentration of a single component or multiple components of a sample in combination with an instrument with a signal detection function. test strip card. Background technique [0002] Colloidal gold immunochromatography (Gold-Immunochromatography Assay, GICA) has been widely used in various aspects of immunoassays. It uses a microporous membrane as a carrier, and uses the capillary action of the microporous membrane to make it drop on one end of the membrane strip. The liquid sample slowly seeps to the other end of the microporous membrane. If there are specific antigens or antibodies in the liquid, they can be combined with immunogold and then combined with the corresponding antibody or antigen coated on the micr...

Claims

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Application Information

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IPC IPC(8): G01N33/558
CPCG01N33/558G01N33/588G01N2800/00G01N33/58G01N33/54388
Inventor 马义才顾敏马灵
Owner CHENGDU LINGYU BIOTECH
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