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A traditional Chinese medicine external preparation for treating children's secretory otitis media and preparation method thereof

A technology for secretory otitis media and external preparations, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, antibacterial drugs, etc., can solve the problems of several weeks of treatment cycle, not recommended use, and insignificant curative effect, reaching The effect of short healing time, no dependence, and less resistance to drugs

Active Publication Date: 2016-06-22
安徽东盛友邦制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Existing traditional Chinese medicines are less effective in treating secretory otitis media.
Most of the medicines for treating otitis media in the prior art use western medicines to reduce inflammation. For children, there are many side effects, so it is not recommended to use them;

Method used

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  • A traditional Chinese medicine external preparation for treating children's secretory otitis media and preparation method thereof
  • A traditional Chinese medicine external preparation for treating children's secretory otitis media and preparation method thereof
  • A traditional Chinese medicine external preparation for treating children's secretory otitis media and preparation method thereof

Examples

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Effect test

preparation example Construction

[0054] The preparation method of external ointment of the present invention:

[0055] Distill 1200g of Goose Bubiograss, 1300g of mint, 1300g of Qingdai, 1400g of borneol, and 1200g of Baihe and 1200g of borneol into crystals according to the stated parts, and make it into component 1 for later use; 1100g, Toosendan 1300g, Phellodendron 1200g, Comfrey 1400g, Salvia miltiorrhiza 1300g, Dandelion 1400g, Atractylodes 1300g, Angelica dahurica 1,400g, add 5-10 times the amount of 60-90% ethanol to soak for 1-2 hours, heat extraction twice, 1-2 hours each time, remove the supernatant, combine the extracts, filter through 80-120 mesh, and then ultra-filter through an ultra-filtration column with a cut-off molecular weight of 5000-10000, and concentrate the ultra-filtrate under reduced pressure when the relative density is 80 °C The extract of 1.36 is heated and concentrated for 30 minutes to 45 minutes, and the concentrated solution is left to stand to form an extract, and the medici...

Embodiment 1

[0123] Embodiment 1, Feng, female, 2 years old, date of visit on September 6, 2010, the parent readme sick child is with double ear feeling of fullness, distant hearing and hearing loss as main symptoms after upper respiratory tract infection. Because the earache is not obvious and the child's main complaint is unclear, the parents only found out when the child's hearing was affected. The ear specialist examination showed that the tympanic membrane was amber or orange, and air-liquid levels or bubbles could also be seen, and the activity of the tympanic membrane decreased. Affect speech and language development, treatment: external preparations are: Goose Bubivora 12g, Nepeta 12g, Sophora flavescens 11g, Toosendan 12g, Borneol 12g, Phellodendron 12g, Scutellaria baicalensis 11g, Baiji 12g, Mint 13g, Qingdai 12g, Comfrey 12g, Danshen 12g, Dandelion 12g, Atractylodes 11g, Angelica dahurica 12g, make drops. Three times a day. 7d is a course of treatment. Clean the left side and...

Embodiment 2

[0124] Embodiment 2: Liu, man, 6 years old, went to a doctor in November, 2011. Upper respiratory tract infection caused half a month of stuffiness in the right ear. He was treated for "upper respiratory tract infection" in another hospital for 5 weeks, but the symptoms did not relieve. The main symptoms were the parents' self-reported feeling of fullness in both ears, distant hearing and hearing loss. The tympanic membrane was intact, and the invagination was grayish yellow; audiometry showed conductive deafness in the right ear, and the air conduction decreased by 40db; the tympanic membrane was pumped and there was secretion. Red tongue, slow pulse. A diagnosis of secretory otitis media was made. Treatment: External preparations are: Goose Bubivora 11g, Nepeta 13g, Sophora flavescens 11g, Toosendan 12g, Borneol 12g, Phellodendron 12g, Scutellaria baicalensis 11g, Baiji 12g, Mint 13g, Qingdai 12g, Comfrey 12g, Salvia miltiorrhiza 12g , Dandelion 12g, Atractylodes 11g, An...

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Abstract

The invention discloses a traditional Chinese medicine external preparation for treating pediatric secretory otitis media. The external preparation comprises the following raw materials in parts by weight: 10-20 parts of centipeda minima, 10-20 parts of schizonepeta, 10-20 parts of radix sophorae flavescentis, 10-20 parts of toosendan fruit, 10-20 parts of borneol, 10-20 parts of phellodendron amurense, 10-20 parts of scutellaria, 10-20 parts of rhizoma bletillae, 10-20 parts of mint, 10-20 parts of indigo naturalis, 10-20 parts of lithospermum, 10-20 parts of salvia miltiorrhiza, 10-20 parts of dandelion, 10-20 parts of rhizoma atractylodis and 10-20 parts of radix angelicae. The medicine provided by the invention has good functions of clearing away heat and toxic materials, eliminating dampness and astringing sores, removing necrotic tissue and promoting granulation and exorcising evil and relieving pain, and has the effects of being quick to dry ears, short in treatment course and free of side effect. If being dosed to secretory otitis media patients, the medicine can promote degradation and absorption of secretion, repair perforated tympanic membrane and recover the audition. The traditional Chinese medicine external preparation disclosed by the invention has such functions as resisting inflammation and bacteria, convergence, dehumidification, dredging aperture, relieving pain, etc.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicinal preparation for treating children with secretory otitis media and a preparation method thereof. Background technique [0002] Otitis media with effusion is a non-suppurative inflammatory disease of the middle ear characterized by middle ear effusion and hearing loss, and is one of the common diseases of the ear, nose and throat. Children are more common. After upper respiratory tract infection, the main symptoms are ear fullness and hearing loss. Because the earache is not obvious and the children's main complaints are unclear, parents only find out when the children's hearing is affected, which often delays diagnosis and treatment. Secretory otitis media can cause hearing loss in children and affect speech and language development, so it should be highly vigilant and timely observed and treat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P27/16A61P31/04A61K31/045
Inventor 王茂鑫
Owner 安徽东盛友邦制药有限公司
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