Traditional Chinese medicinal composition for treating rheumatoid arthritis and preparation method thereof

A composition and arthritis technology, applied in the field of traditional Chinese medicine composition for treating rheumatoid arthritis and its preparation, can solve problems such as adverse reactions, increased infection and tumors, and achieve good therapeutic effect, short course of treatment, and less toxic and side effects Effect

Inactive Publication Date: 2014-05-07
刘义刚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, non-steroidal anti-inflammatory drugs are the most commonly used clinical drugs for rheumatoid arthritis, but they have adverse reactions, the main adverse reactions include gastrointestinal symptoms, liver and kidney function damage, and possible increased cardiovascular adverse events; impr

Method used

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preparation example Construction

[0065] Wherein, when the dosage form of the Chinese medicine composition is plaster, its preparation method comprises the following steps:

[0066] a. The raw medicinal materials weighed by weight are added to ethanol with an alcohol concentration of 3 times the total weight of the raw medicinal materials and are 80% ethanol, heated and refluxed for 3 times, each time for 2-5 hours, and the extracts are combined and left to stand to obtain the extraction Liquid one;

[0067] b. adding water to the dregs extracted by ethanol in step a, heating and refluxing to extract twice, each time for 1-3 hours, combining the extracts and standing still to obtain extract 2;

[0068] c. Combine the extract 1 and the extract 2, pump them into a decompression concentration tank, reduce the pressure to 0.03-0.09MPa, concentrate to a temperature of 60-90°C when the relative density is 1.03, and the temperature reaches 75°C-92°C Extraction; continue to heat and concentrate and add polyethylene g...

Embodiment 1

[0076] Embodiment 1 Plaster 1 of the present invention

[0077] Angelica 310g, peony 230g, licorice 230g, astragalus 310g, notopterygium 200g, Morinda officinalis 210g, safflower 240g, blood wind vine 210g, aescin 170g, calamus 130g, turmeric 200g, passepartout 240g, myrrh 230g, Guizhi 250g, licorice 240g, roadside ginger 360g, pine knots 170g, deer 150g, sweet potato vine 320g, smilax 150g and sarsaparilla 140g.

[0078] Its preparation method comprises the following steps:

[0079] a. Weigh all raw medicinal materials according to parts by weight, and add 3 times the total weight of raw medicinal materials to ethanol with an alcohol concentration of 80%, heat and reflux extraction for 3 times, each time for 4 hours, combine the extracts and let stand to obtain the extract one;

[0080] b. adding water to the dregs extracted by ethanol in step a, heating and refluxing to extract twice, each time for 2 hours, combining the extracts and standing still to obtain extract 2;

...

Embodiment 2

[0083] Embodiment 2 plaster 2 of the present invention

[0084] Angelica 350g, peony 170g, licorice 250g, astragalus 350g, notopterygium 180g, Morinda officinalis 190g, safflower 210g, blood wind vine 200g, aescin 160g, calamus 150g, turmeric 190g, passepartout 230g, myrrh 230g, Guizhi 210g, licorice 220g, roadside ginger 290g, pine knots 160g, chrysanthemum 120g, sweet potato vine 280g, smilax 150g, sarsaparilla 130g, salvia miltiorrhiza 170g, ganoderma lucidum 140g and schisandra 250g.

[0085] Its preparation method comprises the following steps:

[0086] a. The raw medicinal materials taken by weight are added into ethanol with an alcohol concentration of 3 times the total weight of the raw medicinal materials and are 80% ethanol, heated and refluxed for 3 times, each time for 3 hours, the extracts are combined and left to stand to obtain an extract ;

[0087] b. adding water to the dregs extracted by ethanol in step a, heating and refluxing to extract twice, each time f...

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating rheumatoid arthritis and a preparation method thereof. The traditional Chinese medicinal composition comprises the following raw medicinal materials: Chinese angelica, peony root, liquorice, astragalus membranaceus, notopterygium root, morinda officinalis, safflower, ventilago leiocarpa benth, scandent schefflera stem and leaf, rhizoma acori graminei, turmeric, liquidambar formosana hance, myrrh, cassia twig, liquorice, hedychium coronarium koen, pine nodular branch, pyrola, ficus tikoua, herba siegesbeckiae and chinaroot greenbrier. The traditional Chinese medicinal composition has the beneficial effects of taking channel-warming, cold expelling, wind-dispelling and dampness eliminating as a treatment principle, and has the advantages of good treatment effect, short course of treatment, small toxic and side effect, uneasy relapse and low cost when used for treating rheumatoid arthritis.

Description

[0001] technical field [0002] The invention relates to a medicine for treating arthritis, in particular to a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method thereof. [0003] Background technique [0004] Rheumatoid arthritis (RA) is a chronic, inflammatory synovitis-based systemic disease of unknown etiology. It is characterized by polyarticular, symmetrical, and aggressive arthritis of the small joints of the hands and feet, often accompanied by involvement of extra-articular organs and positive serum rheumatoid factor, which can lead to joint deformities and loss of function. The pathogenesis of RA may be related to heredity, infection, and sex hormones. The pathology of RA arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of inflammatory cells in the interstitium, the neogenesis of microvessels, the formation of pannus, and the destruction of cartilage and bone ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P19/02A61P29/00
Inventor 谭维勇
Owner 刘义刚
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