Application of paeonol in preparing medicine for resisting eimeria tenella
A technology of Eimeria and paeonol, which is applied in the application field of paeonol in the preparation of anti-Eimeria tenella medicaments
Active Publication Date: 2015-07-15
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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- Abstract
- Description
- Claims
- Application Information
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Problems solved by technology
[0006] So far, there has been no report that paeonol has anti-Eimeria tenella, and it is impossible to infer whether it has anti-Eimeria tenacia based on the known properties of paeonol
Method used
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Effect test
Embodiment 1
[0011] Preparation of peonyol powder: take 5g peonyol (with a content of not less than 99%) and 95g starch and mix well.
[0012] Usage and dosage of powder: Stir the above 100g powder into 100kg feed, and feed according to daily intake.
Embodiment 2
[0014] Preparation of peonyol water-soluble powder: take 2.5g of peonyol (with a content of not less than 99%) and 97.5g of glucose and mix well.
[0015] Usage and dosage of water-soluble powder: Dissolve the above 100g powder in 100 liters of water. The sick chickens should be water-free for 2 hours before the medication, and then fed according to the normal drinking amount.
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The invention discloses application of paeonol in preparing a medicine for resisting eimeria tenella. Paeonol and acceptable auxiliaries are prepared to form powder; the powder is added into a feed, is uniformly mixed, and is used for feeding chicken according to a daily feeding amount; or paeonol water-soluble powder is prepared from paeonol, can be dissolved in water, and can be used for feeding chicken according to a daily feeding amount. Animal infection experiments prove that the anticoccidial index (ACI) of paeonol can be over 180, and paeonol has a good effect of resisting eimeria tenella.
Description
Technical field [0001] The invention relates to a new use of paeonol, in particular to the application of paeonol in the preparation of medicines against Eimeria tenella. Background technique [0002] Chicken coccidiosis is the most important disease that seriously harms the production of intensive chicken industry. The annual economic loss caused by this is as high as 2.5 billion pounds. Its pathogen is Eimeria spp (Eimeria spp). The most harmful is Eimeria tenella (Eimeria tenella). Chemical drug treatment is one of the important measures to control chicken coccidiosis. However, chicken coccidia currently has extensive and serious drug resistance, and there is an urgent need for new anticoccidial drugs to be marketed. [0003] Paeonol, chemical name: 4-methoxy-2-hydroxyacetophenone, 2-hydroxy-4-methoxyacetophenone, 2-hydroxy-4-methoxyacetophenone, 2-hydroxy -4-Methoxyacetophenone; also known as paeonol and paeonol. The molecular formula of this compound is C9H10O3, the molecula...
Claims
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IPC IPC(8): A61K31/12A61K31/222A61P33/02
Inventor 廖申权孙铭飞谢明权戚南山吴彩艳吕敏娜温列娜
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI