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Nutritional compositions comprising a soluble viscous fiber and a polyphenol-containing plant extract

A nutritional composition and plant extract technology, applied in the direction of drug combination, plant raw materials, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2014-06-18
ABBOTT LAB INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While this allows the viscosity to be adjusted in the nutritional composition, the health effects provided by the composition, such as controlling postprandial blood sugar levels, can be compromised

Method used

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  • Nutritional compositions comprising a soluble viscous fiber and a polyphenol-containing plant extract
  • Nutritional compositions comprising a soluble viscous fiber and a polyphenol-containing plant extract
  • Nutritional compositions comprising a soluble viscous fiber and a polyphenol-containing plant extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] In this example, various water-soluble dietary fibers (Sunfibre®, Nutriose®, WPG® yeast beta-glucan and Barliv®) alone or in combination with Salacinol (Salacia oblonga extract D) were analyzed, Effect on blood glucose levels after a 30-minute meal. Prediabetic (obese rats) and diabetic animal models were evaluated.

[0106] Postprandial blood glucose levels were assessed in prediabetic (obese) and diabetic Zucker male rats and diabetic male mice approximately 6-8 weeks of age. Initially, animal body weights were recorded and basal blood glucose measurements were taken prior to fasting. Animals were fasted overnight and then randomized and assigned to different experimental groups based on their basal blood glucose levels (n=5-7 per group).

[0107] Various sample compositions of water soluble fiber and / or Salacinol were prepared. To formulate the sample compositions, a cornstarch suspension was first prepared by mixing 1 gram of cornstarch with 10 ml of 0.5% Tween-8...

Embodiment 2

[0115] In this example, the blood glucose lowering effects of barley-derived β-glucan (Barliv™) and yeast-derived β-glucan (WGP™) in prediabetic (obese) and diabetic animal models were compared . The effect was assessed at postprandial time points of 30 minutes, 60 minutes, 90 minutes and 120 minutes.

[0116] The effect on postprandial blood glucose levels was assessed in obese and diabetic Zucker male rats and diabetic male mice approximately 6-8 weeks of age. Initially, body weights of these animals were recorded before fasting and before basal blood glucose measurements. Animals were fasted overnight and then randomized and assigned to 3 different experimental groups (n=9 each) based on their basal blood glucose levels.

[0117] A cornstarch suspension was prepared by mixing 1 gram of cornstarch with 10 ml of 0.5% Tween-80 / distilled water. This cornstarch suspension was administered to a control group. A second suspension was prepared using the cornstarch suspension pr...

Embodiment 3

[0123] In this example, the viscosity of a composition comprising an IVF system with or without the addition of Salacia salacia extract was analyzed.

[0124] A composition comprising an IVF system (IVF) was prepared by mixing an IVF system comprising guar gum and maltodextrin (in a weight ratio of 1:0.5) with vitamin C, vitamin D and chromium picolinate in water at room temperature (25°C) . A second composition (IVFSOE) was prepared by first preparing a solution of Salacia oblonga extract D (2.5 mg / ml) in water at 25°C. This solution was used to dissolve an IVF system including guar gum and maltodextrin (in a weight ratio of 1:0.5) with vitamin C, vitamin D and chromium picolinate. Final concentrations for IVF and IVF SOE solutions were: IVF, 7.5 mg / ml; vitamin C, 1.88 mg / ml; vitamin D, 0.015 mg / ml; and chromium picolinate, 0.0198 mg / ml.

[0125] The viscosity of the solution at 25°C was measured on an ARES-LS1 rheometer using a 32mm coquette geometry. Measurements were pe...

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Abstract

Disclosed are nutritional compositions comprising a soluble viscous fiber and a polyphenol-containing plant extract. The viscosity of the nutritional compositions may be adjusted and controlled without varying the concentration of the soluble viscous fiber in the composition by including the polyphenol-containing plant extract.

Description

technical field [0001] The present disclosure relates to nutritional compositions comprising soluble viscous fiber and polyphenol-containing plant extracts. The soluble viscous fiber may be part of an induced viscosity fiber (IVF) system further comprising soluble carbohydrates. By adding polyphenol-containing plant extracts, by adding polyphenol-containing plant extracts and freezing and thawing the resulting solution, or by adding polyphenol-containing plant extracts that have been frozen and thawed prior to addition to the soluble viscous fiber solution, the viscosity of the nutritional composition can be varied and controlled. technical background [0002] Diabetes mellitus is a carbohydrate metabolism disorder caused by insufficient insulin production, or decreased sensitivity to insulin. In people with diabetes, the body's normal ability to use glucose is impaired, raising blood sugar levels. Excess levels of glucose are excreted in the urine as more glucose accumul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/30A23L1/308A61K36/82A61K36/37A61P3/10A23L33/00
CPCA23L1/3002A23L1/308A61K36/87A23L1/296A61K36/736A23L1/1016A61K36/37A23L1/3082A61K36/82A61K36/605A61K36/8998A23L7/115A23L33/105A23L33/21A61K36/185A23L33/40A23L33/24A61P3/10
Inventor M-B.斯克尔丁N.K.埃登斯V.A.穆斯塔德
Owner ABBOTT LAB INC
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