A kind of anti-fatigue extract, its raw material composition, preparation method and application

A raw material composition and extract technology, applied in the directions of drug combination, plant raw material, antidote, etc., can solve the problems of lack of drugs and unsatisfactory effect, and achieve the improvement of glycogen reserve, anaerobic and aerobic metabolism ability, Well-formulated effect

Inactive Publication Date: 2016-12-28
SHANGHAI INST OF PHARMA IND CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide an anti-fatigue extract, its raw material composition, preparation method and application thereof in order to overcome the defects of lack of drugs and unsatisfactory effects in the treatment of fatigue syndrome in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The extraction of embodiment 1 medicinal plant

[0032] About 40% by weight of ginseng; about 25% by weight of epimedium; about 10% by weight of eleuthero; about 10% by weight of chive seeds; about 10% by weight of Angelica dahurica; about 5% by weight of Hovenia dulcis. Add 6-10 times the volume of water, soak for 1 hour, extract twice, decoct at 80°C for 0.5-2.5 hours each time, concentrate to a relative density of 1.2 (the temperature when testing the relative density is 60°C) . Vacuum dried to obtain a dry extract, crushed through a 80-mesh sieve.

Embodiment 2

[0033] Example 2 Biological Evaluation

[0034] In the following biological experiments, the effect of the anti-fatigue extract on the anti-fatigue of mice was mainly investigated

[0035] (1) Experimental animals: ICR male mice, weighing 20-22 g, aged 8-9 weeks, were housed in separate cages and randomly divided into experimental groups and control groups.

[0036] (2) Experimental method

[0037] (1) Feeding method of animals: the experimental group was fed with 40mg / kg per day, and the control group was fed with the same volume of water for 14 consecutive days, and the indicators were measured on the 15th day of the experiment.

[0038] (2) Determination of liver glycogen content: Immediately after the mice were sacrificed by decapitation, the liver was taken to measure the liver glycogen content by anthrone colorimetry.

[0039] (3) Determination of muscle glycogen content: the muscle glycogen content was measured by anthrone colorimetric method using the muscles of both...

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PUM

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Abstract

The invention discloses an anti-fatigue extract, a raw material composition thereof, a preparation method and applications of the anti-fatigue extract. The raw material composition of the anti-fatigue extract comprises the following components in percentage by weight: 3% to 80% of ginseng, 3% to 80% of epimedium, 3% to 80% of acanthopanax, 3% to 80% of Chinese chive seed, 3% to 80% of dahurian angelica root, and 3% to 80% of hovenia dulcis thunb. The preparation method of the anti-fatigue extract comprises the following steps: adding a solvent into the raw material composition of the anti-fatigue extract; soaking the composition for a while; then decocting, extracting, and condensing so as to obtain extract, and finally drying the extract so as to obtain the anti-fatigue extract. The formula of the anti-fatigue extract is reasonable. It has been proved by pharmacological experiments and clinical cases that the anti-fatigue extract actually has an anti-fatigue effect. Moreover, the anti-fatigue extract can improve the glycogen reserve in human boy, improves the anaerobic metabolism performance and aerobic metabolism performance of human boy, and strengthens the tolerance ability when human body is under a large burden.

Description

technical field [0001] The invention relates to an anti-fatigue extract, its raw material composition, preparation method and application. Background technique [0002] Chronic Fatigue Syndrome (CFS) is a group of systemic syndromes mainly characterized by long-term extreme fatigue (including physical fatigue and mental fatigue), accompanied by headache, sore throat, muscle and joint pain, mental fatigue, and depression , insomnia, forgetfulness, slow thinking and inattention and other symptoms. In 1988, it was officially named by the Centers for Disease Control and Prevention in the United States, and it was also officially named and identified as a disease by the ninth edition of "Practical Internal Medicine" in my country. Its basic feature is extreme fatigue for a long time, which cannot be relieved after rest, and there are generally no abnormal findings in physical examination and routine laboratory examination. [0003] Chronic fatigue syndrome is divided into sever...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8962A61P39/00
Inventor 叶庆华昌军
Owner SHANGHAI INST OF PHARMA IND CO LTD
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