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Medicine for treating heart-kidney disorder schizophrenia and preparation method thereof

A technology of schizophrenia and topical medicine, applied in the field of pharmacy, can solve the problems of many adverse reactions, aggravation of the disease, high price, etc., and achieve the effect of no toxic side effects, not easy to relapse, and high safety

Inactive Publication Date: 2016-07-13
THE AFFILIATED HOSPITAL OF QINGDAO UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(4) Disorders of will and behavior. Most patients have decreased or even lack of will, manifested as reduced activities, being alone, passive behavior, lack of due enthusiasm and initiative, decreased interest in work and study, no concern for the future, and lack of concern for the future. No definite intention, some patients may have some plans and intentions, but seldom carry out
[0005] Currently, long-acting injections such as risperidone and paliperidone are commonly used in the treatment of schizophrenia by western medicine. The treatment of schizophrenia by western medicine takes a long time, has many adverse reactions, and is prone to drug resistance. There are fewer types of drugs and limited choices. , and the price is expensive, the patient's economic burden is heavy, and the patient's long-term social and psychological problems will also bring mental pressure, and even aggravate the condition, causing great pain to the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0085] When the dosage form of the medicine for internal administration is an oral liquid, its preparation method comprises the following steps:

[0086] In the first step, mix gardenia, bamboo leaves, earthworm, shouwu and roses, add ethanol with an alcohol concentration of 55% to 65% in an amount 3 to 5 times that of the mixture, and reflux extraction for 2 to 4 times. Each time for 2 hours to 3 hours, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.30 to 1.32 at 70°C, and set aside;

[0087] The second step is to mix the remaining raw medicinal materials in proportion, add 3 to 5 times the amount of water relative to the mixture, boil for 2 to 4 hours, filter, and concentrate to a paste with a relative density of 1.27 to 1.29 at 70°C;

[0088] The third step is to mix the paste obtained in the first step and the second step, and dry under reduced pressure and vacuum at 55°C to 65°C to obtain a dry paste;

[0089] In the f...

Embodiment 1

[0101] Embodiment 1 oral liquid

[0102] The embodiment of the present invention provides an oral medicine for treating heart-kidney disorder schizophrenia. 15 parts by weight of bamboo leaves, 21 parts by weight of Coptis chinensis, 12 parts by weight of ginseng, 7 parts by weight of raw land, 12 parts by weight of Scrophulariaceae, 5 parts by weight of buffalo horn, 7 parts by weight of stone, 12 parts by weight of earthworm, 15 parts by weight of crow, 22 parts by weight of rose, 12 parts by weight of calyx, 17 parts by weight of honeycomb, 7 parts by weight of cat's claw, 19 parts by weight of silkworm, 12 parts by weight of bamboo leek, 11 parts by weight of geranium yellow, 15 parts by weight of bellflower Parts by weight, Lily 21 parts by weight, Asparagus 15 parts by weight, Polygonatum 11 parts by weight, Polygonatum 12 parts by weight, Lycium barbarum 21 parts by weight, Ligustrum lucidum 14 parts by weight, Mulberry 21 parts by weight, Tortoise shell 6 parts by weig...

Embodiment 2

[0110] Example 2 tablet

[0111]The embodiment of the present invention provides an oral medicine for treating heart-kidney disorder schizophrenia. 20 parts by weight of bamboo leaves, 25 parts by weight of coptis, 10 parts by weight of ginseng, 5 parts by weight of raw land, 10 parts by weight of Scrophulariaceae, 3 parts by weight of buffalo horns, 10 parts by weight of pebbles, 10 parts by weight of earthworm, 10 parts by weight of blackberry, 25 parts by weight of roses, 15 parts by weight of calyx plum, 25 parts by weight of honeycomb, 5 parts by weight of cat's claw, 25 parts by weight of silkworm, 10 parts by weight of bamboo leek, 5 parts by weight of geranium yellow, 10 parts by weight of bellflower Parts by weight, Lily 25 parts by weight, Asparagus 10 parts by weight, Polygonatum 15 parts by weight, Polygonatum 10 parts by weight, Lycium barbarum 15 parts by weight, Ligustrum lucidum 10 parts by weight, Mulberry 15 parts by weight, Tortoise shell 3 parts by weight, ...

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PUM

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Abstract

The invention discloses a medicine for treating the heart and kidney imbalanced schizophrenia and a preparing method thereof. The medicine comprises an oral medicine and an external medicine. The oral medicine comprises raw medical materials including gypsum rubrum, cape jasmine, bamboo leaves, coptis chinensis, bistort rhizome, dried radix rehmanniae, radix scrophulariae, cornu bubali, chlorite schist, lumbricus, radix polygoni multiflori preparata, flos rosae rugosae, prunus mume, apiary, radix ranunculi ternate, stiff silkworm, bamboo juice, tabasheer, platycodon grandiflorum, lily, asparagus cochinchinensis, radix polygonati officinalis, sealwort, fructus lycii, glossy privet fruit, mulberry, tortoise shell, folium artemisiae argyi, root of Chinese trichosanthes, spina date seed, platycladi seed, valerian, polygala tenuifolia and acorus gramineus. The external medicine comprises the raw medical materials including angelica sinensis, Chinese prickly ash, polygala tenuifolia, cinnamon, lotus root starch, bighead atractylodes rhizome, aloe and costustoot. The medicine for treating the heart and kidney imbalanced schizophrenia has the advantages that the theory of traditional Chinese medicine is utilized, nourishing yin, suppressing the excessive yang and restoring normal coordination between the heart and the kidney are primary, the medicine has the effects of being quick in effect, definite in therapeutic effect and high in safety performance in treating the heart and kidney imbalanced schizophrenia, no toxic and side effect is produced, and the heart and kidney imbalanced schizophrenia is not prone to relapse.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a medicine for treating heart-kidney disorder schizophrenia and a preparation method thereof. Background technique [0002] Schizophrenia is a group of severe mental illnesses of unknown etiology, mostly in young adults with slow or subacute onset, clinically manifested as a syndrome with various symptoms, involving obstacles in perception, thinking, emotion, and behavior and incoordination of mental activity. Patients generally have clear consciousness and basically normal intelligence, but some patients may experience cognitive impairment during the course of the disease. The course of the disease is generally protracted, showing recurrent attacks, aggravation or deterioration, and some patients eventually develop decline and mental disability, but some patients can maintain recovery or basically recovery after treatment. [0003] Schizophrenia is a clinical syndrome compose...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K36/886A61K36/896A61P25/18A61K35/64A61K35/586A61K35/62A61K35/32A61K33/26
Inventor 李慧刘广义张笛曹永献张娜娜刘冰
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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