Beautiful millettia root wall-broken preparation
A Niu Dali and preparation technology, which is applied in the direction of anti-inflammatory agents, non-central analgesics, medical preparations of non-active ingredients, etc., can solve the problems of loss of active ingredients, easy moisture absorption, deterioration, etc., and achieve good disintegration And stability, simple granulation process, easy disintegration and dispersion
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Embodiment 1
[0036] Take Niu Dalijing medicinal material, coarsely pulverize it into a coarse powder of about 100 mesh, and ultrafinely pulverize it into a powder with a particle size of 90% or less in the ultrafine powder, and add ethanol-water solution (the mass fraction of ethanol is 30%) Soft materials are produced by wet method, the ratio of solution to superfine powder is 0.4:1 (by weight), after mixing, a 10-mesh sieve is pre-installed, the extrusion speed is 50r / min, and the extrusion force is 1MPa to produce wet granules. The granules are placed in a hot air circulation oven, set the drying temperature at 85°C, and dried for 2.5 hours to dryness.
[0037]
[0038] Note: The full score is 10.
Embodiment 2
[0040] Take Niu Dalijing medicinal material, coarsely pulverize it into a coarse powder of about 100 mesh, and ultrafinely pulverize it into a powder with a particle size of 90% or less than 45 μm in the ultrafine powder, and add ethanol-water solution (the mass fraction of ethanol is 40%) Soft materials are made by wet method, the ratio of solution to superfine powder is 0.5:1 (by weight), after mixing, a 10-mesh sieve is pre-installed, the extrusion speed is 70r / min, and the extrusion force is 0.7MPa to make wet granules. The wet granules were transferred to a vacuum microwave drying oven, the drying temperature was set at 45° C., and dried for 0.75 h until dry. After the granules were sized and sieved, the Niu Dali wall breaking preparation was obtained.
[0041]
[0042] Note: The full score is 10.
Embodiment 3
[0044] Take Niu Dalijing medicinal material, coarsely pulverize it into a coarse powder of about 100 mesh, and then superfinely pulverize it into a powder with a particle size of 90% or less of 45 μm in the ultrafine powder, and add ethanol-water solution (the mass fraction of ethanol is 60%) Soft materials are made by wet method, the ratio of solution to superfine powder is 0.8:1 (by weight), after mixing, pre-installed 20-mesh sieve, the extrusion speed is 80r / min, and the extrusion force is 0.3MPa to make wet granules. The wet granules were placed in a hot air circulation oven, set the drying temperature at 85°C, dried for 2.5 hours until dry, and the whole granules were sieved to obtain the Niu Dali wall breaking preparation.
[0045]
[0046] Note: The full score is 10.
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