46results about How to "Simple granulation process" patented technology

The invention relates to a topiramate medicine composition. In the composition, pregelatinized starch is added, the stability of the active components of topiramate is increased, and therefore the quality and security of the composition can be ensured. In the composition, the pregelatinized starch also plays a role of a dry binder, the hardness and the friability of the composition are ensured, the amounts of auxiliary materials are decreased, and the cost is saved. The invention also relates to a preparation method for the topiramate medicine composition. The preparation method comprises a dry granulation technology. The preparation method has simple technology. The finished products after granulation are epigranular, which is convenient for storage and transportation. The topiramate medicine composition is suitable for industrialized production.

The invention relates to the field of starch production, in particular to a method for preparing soluble starch. The method is characterized in that a bio-enzyme enzymolysis secondary acidification technical route is adopted to produce the soluble starch and comprises the following steps of: adding alpha-amylase to 40 percent corn starch milk; degrading with bio-enzyme and then removing liquid; then dispersing chain scission corn starch into an aqueous solution; carrying out secondary acid denaturation; and neutralizing, removing liquid and dynamically drying to obtain a finished product.

The invention relates to the technical field of Chinese herbal preparations, specifically to a wall-broken tall gastrodia tuber preparation. The wall-broken tall gastrodia tuber preparation is prepared by crushing tall gastrodia tuber into wall-broken powder, then carrying out ethanol-water wet granulation, carrying out extrusion forming at a certain rotating speed and then carrying out drying. The prepared wall-broken tall gastrodia tuber preparation has high bioavailability, good stability and good disintegration performance.

The invention provides catalyst particles for air purifiers and a method for forming the same by means of layer-by-layer cladding. The method includes acquiring core-shell structures by means of layer-by-layer cladding in particle forming procedures; manufacturing cores from selective clay mineral materials; cladding catalysts on the outsides of the cores; cladding safe and harmless inorganic porous materials such as activated carbon on the outermost layers of the cores by the aid of non-perishable inorganic adhesive in cladding procedures to obtain the spherical catalyst particles. The safe and harmless inorganic porous materials are used as framework materials. The spherical catalyst particles have uniform particle sizes, are high in catalytic activity and are non-perishable and non-mildew when stored at the room temperature for a long time The catalyst particles and the method have the advantages that the material adding speeds are automatically controlled, so that the uniformity of particle structures can be guaranteed; the spherical catalyst particles prepared by the aid of the method are high in catalytic efficiency, are non-perishable, have the uniform particle sizes and are safe and healthful.

The invention belongs to the technical field of glipizide controlled release tablets, and particularly relates to a double-chamber osmotic pump type glipizide controlled release tablet and an industrial production method. The double-chamber osmotic pump type glipizide controlled release tablet consists of a drug layer, a propelling layer, a rigid semi-permeable membrane, a drug release small holeand a moisture-proof layer; the drug layer takes polyethylene glycol 6000 as a carrier, granulation is carried out by a hot melting method, an organic solvent is not used, and low-power laser round punching is carried out to prepare the double-chamber osmotic pump type glipizide controlled release tablet. The double-chamber osmotic pump type glipizide controlled release tablet and the industrial production method have the advantages of simple granulation process, less equipment investment, high production efficiency, low energy consumption and suitability for industrial production. The produced controlled release tablet is good in stability and convenient to store and transport; organic solvent residues are completely avoided in a granulation process; in a double-layer tabletting process,the technical problem of color mixing is solved, the requirement on equipment performance is lowered, and the service life of the equipment is prolonged.

The invention relates to a Chinese medicine preparation, and in particular relates to a beautiful millettia root wall-broken preparation. The beautiful millettia root wall-broken preparation is prepared as follows: crushing beautiful millettia root into wall-broken powder, then on the basis of quality control of an ethanol solution and the wall-broken powder, granulating by use of an ethanol-water wet method, extruding for forming at a certain rotating speed and drying, the method is high in granulation rate, and the prepared beautiful millettia root wall-broken preparation is high in bioavailability, strong in stability, and good in disintegration.

The invention relates to a Chinese medicine preparation, and in particular relates to an American ginseng wall-broken preparation. The American ginseng wall-broken preparation is prepared as follows: crushing American ginseng into wall-broken powder, then on the basis of quality control of an ethanol solution and the wall-broken powder, granulating by use of an ethanol-water wet method, extruding for forming at a certain rotating speed and drying, the method is high in granulation rate, and the prepared American ginseng wall-broken preparation is high in bioavailability, strong in stability, and good in disintegration.

The invention relates to the technical field of Chinese herbal preparations, specifically to a wall-broken red sage root preparation. The wall-broken red sage root preparation is prepared by crushing red sage root into wall-broken powder, then carrying out ethanol-water wet granulation, carrying out extrusion forming at a certain rotating speed and then carrying out drying. The prepared wall-broken red sage root preparation has high bioavailability, good stability and good disintegration performance.

The invention discloses a granulation method for high-polished injection-molded piece resin. The granulation method comprises the following steps: weighing 20-70 parts of polymethyl methacrylate, 10-30 parts of styrene-acrylonitrile copolymer resin, 10-20 parts of a compatilizer, 0.1-1 part of an antioxidant and 0.1-1 part of a lubricating agent; uniformly stirring all the components in parts by weight after all the components are dried; mechanically blending the components in a synclastic double-screw extruder, and granulating the material after the material is cooled and dried through a cold granulator. The granulation technology is simple; special equipment is not needed, and the quality is controllable; when resin particles are used in an injection-molded piece, an injection-molded piece product has excellent weather resistance, higher surface hardness, high glossiness, high brightness and the like; the glossiness of a product is more than 80 degrees (60 degrees) according to a corresponding test standard; the tensile strength is more than 50MPa, and the Rockwell hardness is more than 100.

The invention relates to the technical field of Chinese medicine preparations, and in particular relates to a rhodiola rosea wall-broken preparation. The rhodiola rosea wall-broken preparation is prepared as follows: crushing rhodiola rosea into wall broken powder, then granulating by use of an ethanol-water wet method, extruding for forming at a certain rotating speed and drying, and the prepared rhodiola rosea wall-broken preparation is high in bioavailability, strong in stability, and good in disintegration.

The invention provides a preparation method for powder granules of a ceramic product by applying a wet mixing granulator. The method comprises the following steps: subjecting to-be-processed fine powder to measuring and weighing according to requirements of equipment, then adding the powder into a granulator, adding water or an adhesive solution according to a required proportion, carrying out granulating under stirring, and then adding a bit of powder in the later period of granulating to polish the granules so as to complete molding of the granules in the granulator. According to the invention, during preparation, the fine powder agglomerates since the surface of the fine powder is wetted by a solution, and through complete mixing and stirring by a granulating knife, granule sizes gradually form and grow up, thereby forming uniform wet granules; granulating efficiency of the powder is greatly improved; powder stacking density per unit volume is increased; and a green body and a product press-molded from the powder are improved in performances and can be convenient to produce.

The present invention discloses a water-soluble granule formulation of 2,4-D salt, comprising components in the following weight percent: 5-80% 2,4-D salt (calculated as 2,4-D acid), and a water-soluble filler as the balance. The water-soluble granule formulation of 2,4-D salt has an outstanding control efficiency on annual or perennial Poaceae weeds and some broadleaf weeds in fields of soybean and other Fabaceae plants. The formulation is environment-friendly, and has the advantages of being free of organic solvents and dusts and being easy to measure in comparison to conventional emulsifiable formulation, wettable powder formulation and suspension formulation. The present invention also discloses the preparation method of the formulation. The production process is simple, economical and safe. The whole production process, without the use of dangerous chemicals, is easy to control and operate and has a high safety factor.

The invention belongs to the technical field of coating materials, and discloses a high-shear-resistant brushing type thick slurry water-in-water coating material, a preparation method and an application thereof. The high-shear-resistant brushing thick slurry water-in-water coating material comprises a base paint, a crosslinking protective agent solution, a continuous phase and an associative thickener, wherein the mass ratio of the base paint, the crosslinking protective agent solution, the continuous phase and the associative thickener is 4: 2: 4: 0.2-0.3. The material has the advantages that the prepared high-shear-resistant brushing type thick slurry water-in-water coating material is resistant to high shear in the granulation process by utilizing the cross-linking reaction characteristics among nano materials, namely the process is carried out at any rotation speed of 200-1400 r/min; and the coating material has the advantages of simple process, good and full color point toughness, no color cross-linking after repeated brushing, no color mixing, mass production, good continuity and long storage stability period.