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Sample handling system

A sample processing system and sample technology, applied in the field of sample processing systems, can solve problems such as injection moldable materials and unreliable molds

Active Publication Date: 2014-10-08
F HOFFMANN LA ROCHE & CO AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The reduced thickness of the sidewalls of the compartments may then no longer be reliably manufactured by injection molding because the injection moldable material cannot be reliably injected into the sidewalls with reduced wall thickness (of the 1536 compartments of the test tube microplate) corresponding to the small space of the mold

Method used

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Examples

Experimental program
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Embodiment Construction

[0045] figure 1 A microplate 1 of a sample processing system according to one embodiment of the invention is shown. The microplate 1 comprises a frame 3 and individual mesh inserts 2 that have been attached to the frame 3 . figure 2 shows frame 3 alone, and image 3 show figure 1 The individual grids 2 of the microplate 1, and for the sake of clarity, these figures are described together below. The frame 3 defines the entire lateral profile of the microplate 1 . The outer contour of the frame 3 is rectangular and has the size of a standard microplate 1 . This standard outer profile allows the microplate 1 to be handled using standard equipment designed to handle standard microplates. The insertion height 33 of the frame 3 is generally not limited to specific dimensions but is related to the number of grid inserts 2 accommodated in the frame 3 . In this embodiment, the insertion height 33 of the frame 3 is slightly greater than or equal to the overall height of a single ...

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Abstract

Sample handling system for handling samples contained in tubes (4), each tube (4) having a hollow body, a closed bottom and an open top for accessing the sample contained in the tube (4). The system comprises a micro-plate (1) comprising at least one grid insert (2) having a plurality of compartments. Each compartment comprises one or more side walls laterally confining a through-hole for receiving a said tube (4). The through-hole has a top opening and a bottom opening and extends between the top opening and the bottom opening. A frame (3) to which the at least one separate grid insert (2) is to be attached to form the micro-plate (1). The frame (3) laterally confines a through-opening which is dimensioned to allow for accessing each compartment (21) of the attached at least one grid insert (2) from above and from below. This allows for moving such tube (4) into and out of each compartment (21) through each of the top opening (202) and the bottom opening (203) of the through-hole (201).

Description

technical field [0001] The invention relates to a sample processing system according to the independent claims. Background technique [0002] It is known to use sample handling systems to store and retrieve bulk samples in automated sample banks. Samples can be, for example, aliquots and / or dilutions of chemical or biochemical compounds dissolved in dimethyl sulfoxide (DMSO), or biological samples, and banks of these samples are stored in a frozen state in a humidity-controlled refrigerator. Contained in a -20° or -80° freezer. Samples retrieved from cold storage can be thawed and then used directly for high-throughput screening (HTS) of substances for their activity on specific biological targets of interest or for biological research or experimentation, just as with This can be done in the drug discovery process as well. [0003] A compound processing system of this type capable of processing large quantities of chemical or biological samples is known from US 6,827,907 ...

Claims

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Application Information

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IPC IPC(8): B01L9/06G01N35/02B01L3/00
CPCG01N2035/0405B01L2200/0689B01L2200/025B01L9/06B01L3/5082B01L2300/0609B01L3/50855B01L2300/044B01L2300/021G01N2035/041B01L2300/0829B01L2200/028G01N35/026B01L2200/02B01L3/00G01N35/02B01L3/5085
Inventor 克里斯托夫·法蒂格尔汤姆·基斯林托马斯·祖姆斯坦
Owner F HOFFMANN LA ROCHE & CO AG
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