198 results about "Bulk samples" patented technology

A thermoelectric material comprises core-shell particles having a core formed from a core material and a shell formed from a shell material. In representative examples, the shell material is a material showing an appreciable thermoelectric effect in bulk. The core material preferably has a lower thermal conductivity than the shell material. In representative examples, the core material is an inorganic oxide such as silica or alumina, and the shell material is a chalcogenide semiconductor such as a telluride, for example bismuth telluride. A thermoelectric material including such core-shell particles may have an improved thermoelectric figure of merit compared with a bulk sample of the shell material alone. Embodiments of the invention further include thermoelectric devices using such thermoelectric materials, and preparation techniques. The use of core-shell nanoparticles allows highly uniform nanocomposites to be formed, and embodiments of the invention also includes other materials and devices using core-shell particles.

Devices, systems and methods for use in separating sample materials into different fractions that employ bulk fluid flow for loading of samples followed by electrophoretic separation of the sample material. Devices employ configurations that optionally allow bulk sample loading with some or no displacement of a separation matrix within a separation conduit. Methods of using these devices, and systems that incorporate these devices are also envisioned.

Rapid spectrum assay of multiple samples with infrared light is made possible by devices and methods that increase total light throughput. Multiple wavelength scan with Fourier analysis is combined with large numbers of sample wells located within infrared light compatible solid materials. In particular, very large scale measurement devices and systems for their use are fabricated from lithography and other techniques used for semiconductor processing.

A method and computer program product for distinguishing and sort seeds containing a genetic element of interest from a bulk sample. In various embodiments, the present invention comprises associating a marker with at least some of the seeds containing a genetic element of interest of the bulk sample, exciting the seeds using an electromagnetic energy emitting device, evaluating at least some of the seeds of the bulk sample for the presence or absence of the marker using an evaluating device configured to excite a majority of the surface area of the seeds, and sorting the seeds containing a genetic element of interest based on the presence or absence of the marker. In various other embodiments, the method and computer program product may comprise associating a red fluorescent protein marker with at least some of the seeds containing a genetic element of interest of the bulk sample, evaluating at least some of the seeds of the bulk sample for the presence of the red fluorescent protein marker using an evaluating device, and sorting the seeds containing a genetic element of interest based on the presence of the red fluorescent protein marker. In some embodiments, the red fluorescent protein marker is discernable when excited by a certain energy and the evaluating step comprises exciting the seeds containing a genetic element of interest with the certain energy detecting an emission resulting at least in part from the exciting step.

A method of flow cytometry analyzes a stream of sample material having more than one fluorescing species. The method comprises the steps pf providing a plurality of intensity-modulated excitation light beams each being modulated at a respective unique frequency; directing the intensity-modulated excitation light beams to interact with the sample material; detecting fluorescence emission light from the sample material to provide signal information representative of detected light intensity versus time; and extracting a plurality of component emission signals from the signal information, wherein each component emission signal corresponds to a respective one of the modulated excitation light beams. Apparatus for implementing the method include flow cytometers and bulk sample analytical optical systems. The invention is helpful in determining species concentrations in cases where the fluorescing species have overlapping or substantially the same emission spectra.

The invention discloses a method for detecting ochratoxin A by the magnetic separation of an aptamer-functionalized magnetic nano material and the marking of an up-conversion fluorescent nano material, which is used for detecting the ochratoxin A content of wheat, grains, feeds and products thereof, and the like. In the method, the ochratoxin-specific aptamer-functionalized magnetic nano material is utilized to perform magnetic separation and enrichment reaction on a sample to rapidly condense bulk samples, effectively increase the condensation of the samples by thousands of times, greatly shorten a detection period and improve the detection sensitivity; and simultaneously, the novel ochratoxin A analysis method for realizing rapid sample treatment, analysis and detection is constructed by combining the characteristics of high sensitivity of laser induced fluorescence of the up-conversion fluorescent nano material and capability of effectively avoiding the interference of biological background fluorescence of the samples.

A system, method, and computer program product for separating a seed aliquot from a bulk sample and preparing the seed aliquot for downstream research purposes is provided. The system embodiments may comprise a counter device, which is configured to receive at least a portion of the bulk sample and to separate the seed aliquot from the portion of the bulk sample, and a packaging device, which is configured to receive the separated seed aliquot and to dispense the aliquot into an aliquot container. Other embodiments may include a conveyor system for advancing the bulk sample and/or seed aliquot along a conveyance path that may be determined from a research protocol received from an input source. Various embodiments of the present invention may maintain an identity of the seed aliquot as it is advanced along the conveyance path and may selectively subject the seed aliquot to a variety of processing steps in accordance with the research protocol with little or no manual control or supervision.

The invention provides a method used for determining Bravais lattice of unknown crystal by electron backscatter diffraction. The invention is characterized in that the method comprises the steps as follows: 1) an electron backscatter diffraction spectrum is obtained and the crystal diffraction information in the diffraction spectrum is measured; 2) a two-dimensional reciprocal surface of the crystal is obtained; 3) a three-dimensional reciprocal primitive cell is reconstructed by the two-dimensional reciprocal surface; 4) the cell parameter of the three-dimensional reciprocal primitive cell s worked out according to the width of the Kikuchi band and the angle between the Kikuchi bands in the same Kikuchi electrode; 5) a reciprocal reduced cell of the crystal is solved; 6) the Bravais lattice of the crystal is determined in the reciprocal space; 7) the Bravais lattice of the crystal is determined. In the method, only a scanning electron microscope and an electron backscatter diffraction accessory are used to realize the analysis on unknown lattice of bulk crystals, and the exponential of the Kikuchi band and the Kikuchi electrode in the electron backscatter diffraction spectrum is marked at the same time. The method has no special requirement on the samples to be analyzed, is suitable for quickly analyzing bulk samples, and can be used for analyzing the microstructure morphologies and crystal structure in the buck samples.

The present invention provides an apparatus and method for automated and rapid loading of a large number of samples for mass spectrometric analysis using various ionization methods (e.g. matrix assisted desorption by laser bombardment (MALDI) and atmosperic pressure ionization (API) methods such as electrospray). The aparatus utilizes microtiter plates to hold the sample, optical elements (e.g. fiber optic) to facilitate automated transport of the ions, and a multiple part capillary comprising at least two capillary sections joined with airtight seal by a union for use in mass spectrometry (particularly with ionization sources) to transport ions between pressure regions of a mass spectrometer for analysis is described herein. Preferably, the capillary is useful to transport ions from an elevated pressure ionization source to a first vacuum region of a mass analysis system.

A method for distinguishing and sorting seeds containing a genetic element of interest from a bulk sample. In various embodiments, the present invention comprises associating a marker with at least some of the seeds containing a genetic element of interest of the bulk sample, exciting the seeds using an photonic emitting device, evaluating at least some of the seeds of the bulk sample for the presence or absence of the marker, and sorting the seeds containing a genetic element of interest based on the presence or absence of the marker. In various other embodiments, the method may comprise associating a red fluorescent protein marker with at least some of the seeds containing a genetic element of interest of the bulk sample, evaluating at least some of the seeds of the bulk sample for the presence of the red fluorescent protein marker using an evaluating device, and sorting the seeds containing a genetic element of interest based on the presence of the red fluorescent protein marker. In some embodiments, the red fluorescent protein marker is discernable when excited by a certain energy and the evaluating step comprises exciting the seeds containing a genetic element of interest with the certain energy and detecting an emission resulting at least in part from the exciting step.

The invention discloses an analytical method of small-size impurities in steel. The technical scheme adopted by the method comprises the steps of: (1) electrolyzing a sample in neutral organic electrolyte under constant current and voltage; (2) filtering a solution rich in a large amount of impurity particles after electrolysis by a filter membrane with superfine aperture so as to settle the small-size impurity particles on the membrane; (3) taking off the filter membrane, bonding the membrane on a supporting table and putting the filter membrane on a scanning electron microscope for observation, taking morphology photos and analyzing energy spectrum components; and (4) processing data, and conducting three-dimensional statistic analysis to all impurities in the sample or statistic analysis to specified type of impurities. The analytical method of small-size impurities in steel solves the problems that the electrolysis extraction method of bulk sample is not applicable to the traditional analysis method of small-size impurities, the impurities cannot be displayed completely in the analysis of impurities on a two-dimensional polishing surface, and the analysis of components is interfered with a matrix.

Methods are presented for separating the effects of background doping density and effective minority carrier lifetime on photoluminescence (PL) generated from semiconductor materials. In one embodiment the background doping density is measured by another technique, enabling PL measurements to be analysed in terms of effective minority carrier lifetime. In another embodiment the effective lifetime is measured by another technique, enabling PL measurements to be analysed in terms of background doping density. In yet another embodiment, the effect of background doping density is removed by calculating intensity ratios of two PL measurements obtained in different spectral regions, or generated by different excitation wavelengths. The methods are particularly useful for bulk samples such as bricks or ingots of silicon, where information can be obtained over a much wider range of bulk lifetime values than is possible with thin, surface-limited samples such as silicon wafers. The methods may find application in solar cell manufacturing for improving the manufacture of silicon ingots and bricks, or for providing a cutting guide for wafering.

The invention relates to a medical reagent, in particular to a kit for determining glycated serum protein, which comprises a reagent R1 and a reagent R2, wherein the reagent R1 contains buffer solution of 20mmol/L, surfactants accounting for 0.5 percent of the reagent R1, anti-interference substances of 0.05-0.1mmol/L, stabilizers of 0.5-1g/L, and preservatives of 0.05g/L. The reagent R2 contains fructosyl amino acid oxidase of 20mmol/L, horseradish peroxidase of 20KU/L, chromogen of 0.1mmol/L, preservatives of 0.05g/L and stabilizers of 0.5-1g/L. Compared with the prior art, when the kit for determining glycated serum protein is used, the glycated serum protein can be determined in an enzymatic method, the HPLC (high performance liquid chromatography) can be completely substituted, and the kit can be applied to clinical laboratories for determination of large bulk samples and can be operated easily. Moreover, the kit has a wide linear scope and high value of application, and the cost of the kit is low.

The invention relates to a method for testing a material heat conductivity coefficient through a transient plane heat source method; the method is achieved through a testing device, and the testing device mainly comprises a probe, an electrical bridge testing system, and a data acquisition and analysis system; in the electrical bridge testing system, a power supply for supplying power for an electrical bridge is regulated in the range of 0-20 V, and the maximum current does not exceed 1 A. The method can measure various samples such as bulk samples, uniaxial anisotropic samples, thin sheet samples and thin film samples, and is high in control accuracy, short in detection period, and accurate in testing results.

An apparatus and method for optically analyzing samples in a biological sample container containing samples arranged at different locations on the base of the container. An optical acquisition device is provided comprising a detector and an objective. The position of the upper and lower surfaces of the base at each of the sample locations is determined by a confocal polychromatic displacement sensor. Light is collected from each of the sample locations by adjusting the focal plane to be coincident with, or vertically offset from, the upper surface of the base, as determined from the displacement sensor. This allows for rapid scanning of large numbers of samples in a multi-well plate or other biological sample containers.

The invention relates to an intelligent fully-automatic sample preparation system and a method thereof. The system mainly includes a bulk sample temporary-storage and transportation module, a sample preparation module, a full-moisture analysis module, a rejected sample temporary-storage module, a sample bottle packaging module, a sample bottle transportation and storage module and an industrial robot; and the industrial robot is a robot arm, and the bulk sample temporary-storage and transportation, the sample preparation module, the full-moisture analysis module, the rejected sample temporary-storage module and the sample bottle packaging module are arranged on the working radius of the robot arm at intervals along a circumferential direction. The industrial robot transfers sample materials among the bulk sample temporary-storage and transportation, the sample preparation module, the full-moisture analysis module, the rejected sample temporary-storage module and the sample bottle packaging module to realize unattended fully-automatic sample preparation, prepared samples meet lab test requirements, and various problems of existing manual operations are solved.

The invention provides a Bifidobacterium longum LJM002 strain, of which the collection number is CGMCC No.4900. The LJM002 strain is super-sensitive to acephate, and thus, is a working strain for detecting acephate residues in food. The invention also provides a microbiological method for detecting acephate residues in food, which determines whether the residue level of acephate in a food sample to be detected is overproof according to the size of the inhibition zone on the detection culture medium. The method provided by the invention is simple to operate, has the characteristics of low cost and high sensitivity, is suitable for sample detection, and satisfies the detection requirements of Chinese Pesticide Residue Detection Department for mass samples.

A method of forming a sample and performing correlative S/TEM and APM analysis is provided wherein a sample containing a region of interest is cut from a bulk of sample material and formed into an ultra-thin lamella. The lamella is then analyzed with an S/TEM to form an image. The lamella sample and mount may then go through a cleaning process to remove any contamination. The lamella containing the ROI is then embedded within a selected material and is formed into a needle-shaped sample. The needle-shaped sample is then analyzed with the APM and the resulting data is merged and correlated with the S/TEM data.

The present invention provides a 4D biochip containing m 3D biochips having n capillaries, wherein the n capillaries each contain a biological factor, and methods for preparing and using the 4D biochip to provide rapid, efficient assays of large quantities of samples and/or factors.