A virus detector

Abstract

The invention discloses a virus detector, which includes an interdigitated array microelectrode (1), a microfluidic detection pool (2) and an impedance detection module (3); when a sample containing a virus is injected into the microfluidic detection When the pool (2), the antibody or other biorecognition material immobilized on the surface of the interdigitated array microelectrode (1) embedded in the microfluidic detection pool (2) will combine with the virus, resulting in an impedance change, which will pass through the impedance detection module (3) Impedance measurement is carried out, and the standard curve is used for data processing to quickly and quantitatively detect the content of avian influenza virus. The virus detector of the invention has the advantages of fast detection speed, convenient operation, quantitative analysis and on-site detection.

Description

Technical field [0001] The invention relates to the technical field of virus detection, and more specifically to a virus detector. Background technique [0002] In recent years, outbreaks of viral animal diseases have continued to occur, such as avian influenza H5N1, H7N9, etc. According to WHO statistics: Since 2003, animals in 62 countries and humans in 15 countries have been infected with the H5N1 avian influenza virus. Among 649 human cases, 385 have died, with a mortality rate of nearly 60%. The highly pathogenic avian influenza has not only caused huge economic losses, but also seriously threatened the public health security of society. [0003] The key to the prevention and control of viral animal diseases is rapid detection of disease viruses. Taking avian influenza virus as an example, the existing avian influenza virus detection methods mainly include virus isolation method, reverse transcription polymerase chain reaction (RT-PCR) and colloidal gold immunochromatographi...

AI Technical Summary

Problems solved by technology

Virus isolation method is currently the gold standard method for diagnosis and identification, with high sensitivity, but the detection time is too long and takes 7-10 days; RT-PCR is the detection method recommended by the World Health Organization, which takes 3-6 hours and has high sensitivity. However, complex sample pretreatment is required; the test strip detection time is short, usually within 15 minutes, but the sensitivity is low and the false positive rate is high

Existing virus detection methods have shortcomings such as too long time, complicated operation or low accuracy, which to a certain extent restricts grassroots animal disease prevention and control institutions from carrying out rapid screening of animal diseases

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