A kind of paroxetine enteric-coated sustained-release preparation and preparation method thereof
A technology of sustained-release preparations and preparations, applied in pill delivery, pharmaceutical formulations, medical preparations of non-active ingredients, etc.
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Embodiment 1
9
[0030] Preparation:
[0031] (1) Mix paroxetine hydrochloride and hypromellose and sieve to obtain mixed powder a;
[0032] (2) Evenly mix the mixed powder a with lactose and microcrystalline cellulose to obtain the mixed powder b;
[0033] (3) Povidone is prepared into povidone ethanol solution and added to mixed powder b, granulated and dried;
[0034] (4) Press into tablets, enteric-coated, and the weight gain of the coating is 6-8%.
Embodiment 2
0.65
[0037] Preparation:
[0038] (1) Mix and sieve paroxetine hydrochloride, hypromellose and methylcellulose to obtain mixed powder a;
[0039] (2) Evenly mix the mixed powder a with lactose and microcrystalline cellulose to obtain the mixed powder b;
[0040] (3) Povidone is prepared into povidone ethanol solution and added to mixed powder b, granulated and dried;
[0041] (4) Add magnesium stearate and micronized silica gel;
[0042] (5) Press into tablets, enteric-coated, and the weight gain of the coating is 6-8%.
Embodiment 3
[0044] Element
[0045] The preparation method is the same as in Example 1.
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