Plant extract composition applicable to androgenetic alopecia, and preparation method and application thereof

A technology of seborrheic alopecia and plant extraction, which is applied in the field of daily chemicals, can solve the problems of unfavorable formula and application, long-time process, difficult active ingredients, etc., achieves the treatment of seborrheic alopecia symptoms, convenient application, and reduces male The effect of early hair loss

Inactive Publication Date: 2014-12-24
广州市络捷生物科技有限公司
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

The former, through high-temperature cooking, tends to oxidize a large amount of polyphenol components in Chinese herbal medicines or plant compounds, and gelatinize starch, resulting in a black and sticky paste, which is not conducive to formulation and application such as tincture, and its effective The ingredients are also difficult to efficiently release in the boiled paste
The latter method of alcohol immersion requires a long process and is less efficient

Method used

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  • Plant extract composition applicable to androgenetic alopecia, and preparation method and application thereof
  • Plant extract composition applicable to androgenetic alopecia, and preparation method and application thereof
  • Plant extract composition applicable to androgenetic alopecia, and preparation method and application thereof

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preparation example Construction

[0028] The preparation method of the plant extract composition applicable to androgenetic seborrheic alopecia of embodiment 1-4 comprises the following steps:

[0029] a. Crushing and dissolving: Weigh and dry the above-mentioned various raw materials according to parts by weight, pulverize and pass through a 200-mesh sieve, and dissolve with a concentration of 20-80% ethanol as a solvent. The weight ratio of raw materials to solvent is 1: 3~1:10;

[0030] b. Low-temperature and high-pressure-difference extraction: the mixture obtained in step a is obtained in a low-temperature environment of 5-50°C by instantaneously generating a pressure difference to cause the plant cells of the compound to be broken, and the active ingredient overflows to come into contact with the solvent;

[0031] c. Multi-stage membrane filtration: Among them, the filtration temperature is 14-20°C, the pressure is 0.02-0.1mPa, the flow rate is 1.5-3 LPM, and the motor frequency is 45-50Hz.

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Abstract

The invention relates to the field of daily articles, in particular to a plant extract composition applicable to androgenetic alopecia, and a preparation method and application thereof. The plant extract composition comprises a sabal fruit extract, an impatiens balsamina extract, a scutellaria baicalensis extract, a radix sophorae flavescentis extract, a fructus cnidii extract, a ginseng extract, an angelica extract and a pepper extract, and the balance of an ethanol solution, wherein each extract accounts for 0.1-5% of the total weight of the composition. The plant extract composition can take 5alpha-reductase and an androgen receptor as targets simultaneously, can effectively control and eliminate microbial infection of a scalp, has an anti-inflammatory effect, can effectively treat male alopecia seborrhoeica caused by male androgens under a synergistic action of Chinese herbal prescriptions capable of increasing blood microcirculation of the scalp, and reduces the probability of male early hair loss and alopecia areata. By the preparation method, active components in the extracts can be effectively protected, and the active component content of the plant extract composition is 4-20 times higher than that in the conventional method.

Description

technical field [0001] The invention relates to the field of daily chemicals, in particular to a plant extract composition suitable for androgenic seborrheic alopecia, a preparation method and application thereof. Background technique [0002] Seborrheic alopecia, also known as male pattern baldness, androgenetic alopecia, often manifests as greasy, dandruff, obvious itching, progressive hair loss in the frontotemporal area and top, and then a high forehead. Occurs in young men aged 20 to 30, also known as early baldness. Seborrheic alopecia is common disease, frequently-occurring disease in dermatology clinic, is also one of refractory diseases. Because this disease hinders the appearance and affects the appearance, it often brings great mental pressure and psychological burden to the patient, so the research on seborrheic alopecia has been widely paid attention to. [0003] Modern medical research shows that genetic factors are one of the main causes of seborrheic alopec...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q5/02A61Q5/12A61P17/14
Inventor 吴培诚
Owner 广州市络捷生物科技有限公司
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