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Solid ultrasonic coupling agent and preparation method thereof

An ultrasonic coupling agent and coupling agent technology, applied in the direction of echo/ultrasonic imaging agent, etc., can solve problems such as inconvenience, complicated design and use of focused ultrasonic devices, and electrical safety hazards of focused ultrasonic emitting devices, and achieve smooth and clean surfaces and storage And easy to use and economical, good effect of ultrasonic transmission

Inactive Publication Date: 2017-05-31
百仕联创新医学技术(北京)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This operation is more inconvenient
No matter during use or during storage and transportation, if the air redissolves in the liquid couplant, it will lead to a decrease in its acoustic conductivity
This requires the liquid ultrasonic couplant to be kept under airtight conditions at all times, which complicates its transportation, storage and use and reduces its economy
At the same time, the possible corrosion of the transducer due to liquid contact and the potential hazard of liquid leakage to the electrical safety of the focused ultrasound emitting device will complicate the design and use of the focused ultrasound device, resulting in increased economic costs and convenience. decline of sex

Method used

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  • Solid ultrasonic coupling agent and preparation method thereof
  • Solid ultrasonic coupling agent and preparation method thereof

Examples

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Effect test

Embodiment 1

[0058] Content 70% of glucomannan, viscosity 5000mPa · s, grain size 120 mesh food grade konjac powder are dissolved in purified water to obtain 8% aqueous solution of konjac powder. The temperature of the whole dissolution process is controlled at about 45°C. Put the aqueous solution of konjac powder under the vacuum condition of temperature 45°C and -0.09Mpa for 24 hours to fully defoam. Under the condition of vacuum stirring, sodium hydroxide aqueous solution is added into the aqueous solution of konjac fine powder, so that the pH value of the aqueous solution of konjac fine powder rises to 11, and its mass concentration drops to about 6% at the same time. The aqueous solution of alkalized konjac powder is poured into the forming mold, and then the sealed forming mold is placed in a constant temperature box. Slowly heat to 75°C at a rate of 5°C per minute and hold for 3 hours. Pour the cured couplant out of the mold, soak it in clean water for cleaning, rinse and change t...

Embodiment 2

[0060] Content 78% of glucomannan, viscosity 7000mPa·s, grain size 100 mesh food grade konjac powder are dissolved in purified water to obtain 6% aqueous solution of konjac powder. The temperature of the whole dissolution process is controlled at about 30°C. Put the aqueous solution of konjac powder under the vacuum condition of temperature 30°C and -0.09Mpa for 30 hours to fully defoam. Under the condition of vacuum stirring, sodium carbonate aqueous solution is added into the aqueous solution of konjac fine powder, so that the pH value of the aqueous solution of konjac fine powder rises to 10, and its mass concentration drops to about 5% at the same time. The aqueous solution of alkalized konjac powder is poured into the forming mold, and then the sealed forming mold is placed in a constant temperature box. Slowly heat to 90°C at a rate of 5°C per minute and hold for 2 hours. Pour the cured coupling agent out of the mold, soak and clean it in clean water, rinse and change ...

Embodiment 3

[0062] Content 85% of glucomannan, viscosity 10000mPa·s, particle size 80 mesh food grade konjac powder are dissolved in purified water to obtain 2% aqueous solution of konjac powder. The temperature of the whole dissolution process is controlled at about 10°C. Put the aqueous solution of konjac powder under the vacuum condition of temperature 10°C and -0.09Mpa for 36 hours to fully defoam. Under the situation of vacuum stirring, sodium carbonate powder is added in the aqueous solution of konjac fine powder, and the pH value of the aqueous solution of konjac fine powder is raised to 9. The aqueous solution of alkalized konjac powder is poured into the forming mold, and then the sealed forming mold is placed in a constant temperature box. Slowly heat to 100°C at a rate of 5°C per minute and hold for 1 hour. Pour the cured couplant out of the mold, soak it in clean water for cleaning, rinse and change the water every 1 hour. After 5 times, the soaking water was tested to be n...

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Abstract

The invention discloses a solid ultrasonic couplant and a preparation method thereof. The solid ultrasonic couplant has a shape matched with a shape of an ultrasonic transducer of a focused ultrasonic launcher, and is prepared from konjac fine meal as a main raw material, wherein the content of glucomannan in the konjac fine meal is greater than 70%, and the viscosity is greater than 5000 mPa.s. The solid ultrasonic couplant is flexible, is rich in elasticity and smooth in surface, has the sound conduction performance close to water, and has a good ultrasonic conduction effect.

Description

technical field [0001] The invention relates to a solid ultrasonic coupling agent and a preparation method thereof, in particular to a konjac glucomannan solid ultrasonic coupling agent and a preparation method thereof. Background technique [0002] Focused ultrasound therapy has become a relatively mature medical technology. Since ultrasound cannot propagate in the air, current focused ultrasound transmitters all use liquid ultrasound couplant as the conduction medium. The most common liquid ultrasonic couplant is degassed water. Use a fluid-fillable container in front of the transducer of the focused ultrasound transmitter. During focused ultrasound therapy, the liquid ultrasonic coupling agent is first poured into the container as a medium for transmitting ultrasound from the transducer to human tissues. [0003] In the process of filling the container with the perfusion liquid, it is necessary to completely remove the air bubbles to avoid the interference of the air b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K49/22
Inventor 梁晓云王宏图
Owner 百仕联创新医学技术(北京)有限公司
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